Sclerosed liver hemangioma mimicking malignant tumor at MR imaging: Pathologic correlation

This case report illustrates atypical magnetic resonance (MR) imaging findings in a liver hemangioma mimicking a malignant lesion—lower signal intensity than cerebrospinal fluid on T2-weighted spin-echo images and lack of early enhancement on dynamic contrast material—enhanced gradient-echo images. Pathologic analysis demonstrated nearly total replacement of the vascular cavities by dense fibrous tissue. In this rare, sclerosed form, this lesion could not be defined as a hemangioma with MR imaging.     

电动秋千的研制及其在前庭功能研究中的应用

本文介绍了带转椅的电动秋千的研制及其使用,包括其工作原理、结构与控制系统的设计、主要技术性能及其在前庭功能与空间运动病研究中的应用。多年的实验证明,这台电动秋千设计合理,技术指标先进,使用性能良好,是研究前庭功能和空间运动病的实用设备。     

Measurement of degraded fecal hemoglobin-heme to estimate gastrointestinal site of occult bleeding appraisal of its clinical utility

Hemoglobin-heme is variably converted to porphyrin during enterocolic transit. This intestinal converted fraction, as measured by HemoQuant, was elevated as a predictor of the occult bleeding site in 152 patients with discrete lesions. The intestinal converted fraction, expressed as the percentage of total fecal hemoglobin, was similar with upper gastrointestinal and proximal colon lesions. Within the colon, values trended downward with more distal location: means ± standard deviations were 18±14 proximal colon, 16 ±15 sigmoid, and 10±10 rectum. The amount of fecal blood also affected the intestinal converted fraction; correcting for hemoglobin concentration improved separation by site. Corrected intestinal converted fraction values were significantly lower with rectal (P< 0.0005) and sigmoid (P<0.02) lesions than with proximal colon lesions. Unfortunately, large within-site variation caused considerable overlap between sites. We conclude that the intestinal converted fraction is influenced by the site and amount of bleeding. However, its clinical utility is compromised by substantial individual differences in luminal hemoglobin metabolism.Presented in part at the Annual meeting of the American Gastroenterological Association in San Francisco in May of 1986 (Gastroenterology 90:1431, 1986).Supported by the Mayo Foundation.     

白术茯苓汤及其配伍对脾虚大鼠胃肠激素的影响

目的：探讨益气健脾方剂治疗脾虚证的配伍规律。方法：采用苦寒泻下法复制大鼠脾虚模型，运用放射免疫分析法（RIA）检测白术茯苓汤及其与补气药。行气药及除湿药的不同配伍对脾虚大鼠胃泌素（GAS）、胃动素（MTL）及血管活性肠肽（VIP）的含量影响。结果：与正常对照组比较，脾虚模型大鼠GAS、MTL降低（P＜0．01），VIP升高（P＜0．01）；与自然恢复组比较，各治疗组以上部分或全部指标均有不同程度的改善，其中，以综合配伍组改善作用最优。结论：白术茯苓汤的脾虚大鼠胃肠激素的紊乱的某些指标，有一定的改善作用，综合配合组以上指标的改善，优于白术茯苓汤组及其余各配伍组，说明中医关于复方配伍的理论与实践，有其科学价值。     

上消化道出血798例分析

目的　探讨上消化道出血的病因和相关因素。方法　回顾性分析我院 8年来 798例上消化道出血病人的临床资料。结果　男性并发上消化道出血占 80 .2 0 %、女性占 19.80 % ,男性明显高于女性 (χ2 =6 .5 6 ,P <0 .0 5 ) ;青年人、中年人及老年人各占 2 7.82 %、5 7.6 1%和 14 .5 7% (P <0 .0 1) ,老年人合并重度上消化道出血多见 ;不同性别、年龄者出血的原因不尽相同。结论　上消化道出血的病人以消化性溃疡、胃癌、急性胃粘膜损害、食道胃底静脉曲张为最常见的病因 ,性别、年龄等均为上消化道出血的相关因素     

LONG‐TERM OUTCOME OF ENDOSCOPIC BALLOON DILATION IN OBSTRUCTIVE GASTROINTESTINAL CROHN's DISEASE

Background: Gastrointestinal strictures are the most often and serious complication in Crohn's disease. Because of the frequent postoperative recurrence in Crohn's disease, endoscopic therapy of gastrointestinal stricture is one of the best therapeutic options. Method: The present study sets out the results from a prospective study of endoscopic dilation therapy on 48 Crohn's disease patients with severe gastrointestinal stenoses. All patients who could not undergo endoscopic balloon dilation therapy (EBD) were operated on. Results: Long‐term success was attained in 32 of the 48 patients; cumulative avoidance of surgery after EBD was 86% at one year and 71% at three. Second, the most hazardous factor was recurrent inflammation causing restenosis. Patients who had strictures with oral luminal dilatation and patients with frequent recurrence had a tendency to be operated on. As a complication, perforation occurred in two cases (3.3%). Conclusions: EBD therapy for Crohn's stricture in the gastrointestinal tract is recommended before surgical intervention.     

Ghrelin does not stimulate gastrointestinal motility and gastric emptying: an experimental study of conscious dogs

Ghrelin is a peptide that was discovered in endocrine cells of the stomach. However, its action in regulating the fasted and fed motor activity of the digestive tract is not fully understood. In the present study, we examined the effects of an intravenous (i.v.) injection of canine ghrelin on the physiological fasted and fed motor activities in the stomach, duodenum, jejunum and colon of freely moving conscious dogs. An i.v. injection of canine ghrelin released growth hormone in a dose-dependent manner; however, it did not stimulate the motor activity of the digestive tract in either the fasted or the fed state. Moreover, an i.v. injection of high-dose canine ghrelin significantly reduced the motility index in the gastric body in the fasted state. Ghrelin did not accelerate gastric emptying, either. These results differ from previous reports dealing with rodents. It is significant that such results were obtained in research with dogs, which are larger animals.     

御制平安丹治疗晕动病的临床和实验研究

用御制平安丹(下称平安丹)治疗晕动病(运动病)343例,观察结果表明,平安丹服后有效率为92.8%,优于乘晕宁和人丹组(P<0.05～0.01)。平安丹可影响猫前庭感受器,抑制旋转后眼震,起到调节前庭—植物性神经功能的作用;它还能改善动物软脑膜微循环,有助于调整椎基底动脉、前庭通路等区域微循环障碍。以上效果与治疗剂量东莨菪碱(Scopolamine)相似。     

Endoscopic laser pancreatic cystogastrostomy

Traditionally the drainage of pancreatic pseudocysts has been carried out operatively, forming a cystenterostomy. A simple endoscopic method of forming a pancreatic cystogastrostomy with laser is presented. This procedure does not require a general anesthetic, is safe, and allows resolution of symptoms.     

Effect of meal volume on gastric emptying

Abstract While the volume of a liquid meal has been identified as the principal accelerator of gastric emptying of liquids, the relationship between meal volume and gastric emptying of solids has been controversial. With solid foods, the need to reduce solid foods into small particles (trituration) before passage might obscure the effect of meal volume on solid propulsion. To distinguish trituration from driving force as the rate-limiting factor for emptying, 75 (1.6 mm) nylon spheres were fed along with different amounts of steak meals (150, 300 and 600 g), or alternatively, 50, 100 or 200 (1.6 mm) nylon spheres were fed to six dogs with 300 g steak meals. To examine the effect of meal volume on gastric emptying, we studied the effect of different meal volumes on the speed of gastric emptying of liquids (150, 300, 600 and 1200 ml of phosphate buffer) and solids (150, 300 and 600 g of cooked beef steak) in five dogs with duodenal fistulas. Intestinal inhibition was eliminated by diverting all chyme through the fistulas. In the absence of intestinal feedback, we found that gastric emptying of steak and spheres were different in that steak emptying was independent of meal volume (g min^-1 was constant across 150–600 g) while sphere emptying was affected by the number of spheres in the stomach and that liquid emptying was dependent on the meal volume (ml min^-1 increased across 150–1200 ml). Thus, meal volume accelerated gastric emptying provided the process is not rate-limited by trituration.