Diagnostic uses of metal detectors: a review

Metal detectors have been used for diagnostic purposes since 1881. They have been utilised to localise a myriad of foreign objects including bullets, intraocular metallic fragments, swallowed coins and other foreign bodies and medical devices. Rapid detection of metallic objects may facilitate diagnosis or treatment. Metal detectors are diagnostically useful because of their low expense, lack of radiation exposure and ease of use. This article reviews the history of metal detection in the practice of medicine and provides an overview of the utility of metal detectors in current diagnostic practice.     

境外生中医诊断学教学方法探讨

对如何提高境外生中医诊断学教学质量进行探讨,认为应消除语言障碍,提高汉语水平;联系前后内容,注重横向比较;改善教学手段,教学方法多样;授课重点突出,总结归纳要点;合理安排作业,督促课后复习.     

Production of influenza pseudotyped lentiviral particles and their use in influenza research and diagnosis: an update

Pseudotyped viral particles are being used as safe surrogates to mimic the structure and surface of many viruses, including highly pathogenic viruses such as avian influenza H5N1, to investigate biological functions mediated by the envelope proteins derived from these viruses. The first part of this article evaluates and discusses the differences in the production and characterization of influenza pseudoparticles. The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis.     

Snowboarding injuries: a review of the literature and an analysis of the potential use of portable ultrasound for mountainside diagnostics

Snowboarding has become a popular recreational and professional sport. Participants suffer a variety of injuries, especially of the extremities, that require medical evaluation. This article reviews the reported injuries to both leisure and elite athletes. To many, an injured extremity requires travel to a medical facility for accurate evaluation. Musculoskeletal ultrasound is an accurate and portable technology that can be used for real time, mountainside diagnoses of these injuries.     

Accordance and concordance of PCR and NASBA followed by oligochromatography for the molecular diagnosis of Trypanosoma brucei and Leishmania

Objective To evaluate the repeatability and reproducibility of four simplified molecular assays for the diagnosis of Trypanosoma brucei spp. or Leishmania ssp. in a multicentre ring trial with seven participating laboratories. Methods The tests are based on PCR or NASBA amplification of the parasites nucleic acids followed by rapid read‐out by oligochromatographic dipstick (PCR‐OC and NASBA‐OC). Results On purified nucleic acid specimens, the repeatability and reproducibility of the tests were Tryp‐PRC‐OC, 91.7% and 95.5%; Tryp‐NASBA‐OC, 95.8% and 100%; Leish‐PCR‐OC, 95.9% and 98.1%; Leish‐NASBA‐OC, 92.3% and 98.2%. On blood specimens spiked with parasites, the repeatability and reproducibility of the tests were Tryp‐PRC‐OC, 78.4% and 86.6%; Tryp‐NASBA‐OC, 81.5% and 89.0%; Leish‐PCR‐OC, 87.1% and 91.7%; Leish‐NASBA‐OC, 74.8% and 86.2%. Conclusion As repeatability and reproducibility of the tests were satisfactory, further phase II and III evaluations in clinical and population specimens from disease endemic countries are justified.     

多媒体课件在超声诊断教学中的应用

以《超声医学》为指导性文字资料，运用多媒体软件分别制作各个系统的教学课件，针对不同层次学生进行教学，多媒体教学应用取得了良好的教学效果。多媒体课件生动、形象、直观，提高了授课效率和质量。     

执业医师技能考试及其引发的思考

执业医师资格考试制度的实施对提高医师队伍的素质起着重要作用。本文针对近年来执业医师技能考试中发现的问题,探讨了提高医学生临床技能的方法和途径。     

《临床诊断学》课堂双语教学初探

在预防医学本科临床诊断学教学中开展了双语教学,并通过问卷的方式调查分析学生对开展临床医学双语教学的态度和要求,旨在进一步进行双语教学的改革,探索提高临床双语教学质量的方法。     

Comparison between two commercial immunoassays: Dr. Fooke ALLERG-O-LIQ versus Phadia ImmunoCA(R) System in detecting allergen-specific IgE and total IgE values

Objective: Beside patient's history and skin prick testing(SPT) the detection of specific IgE(slgE) represents an important tool of allergy diagnostics. In recent years different technologies for the detection of sIgE have been developed. The objective of this study is the comparison of the ALLERG-O-LIQ with the ImmunoCAP System using seven inhalant and four food allergens. Methods: Sera from patients were collected and tested for sIgE to inhalant(d1, d2, d5, i6, el, e5 and m3) and food allergens(fl, 12, f24, t24) by ALLERG-O-LIQ(Dr. Fooke Laboratorien GmbH) and by ImmunoCAP System(Phadia). Further, samples were also tested for total IgE in both systems. Results: Prevalence of positive test results varied between 0/20(124) and 11/20(e5) for ALLERG-O-LIQ and between 3/18(f23) and 11/20(d1/d5) for ImmunoCAP . The qualitative agreement between both methods was found between 75%(f24) and 100%(d2) depending on the allergen. Overall qualitative agreement for inhalant(n = 140), food(n = 78) and all allergens(n = 218) tested was 92.1%(kappa = 0.84), 83.3%(kappa = 0.58), 89.0%(kappa = 0.77), respectively. Sensitivity, specificity, positive predictive value (PPV), negative predictive value(NPV) and diagnostic efficiency(DE) were found at 88.2%, 95.8%, 95.2%, 89.6%, 92.1%(inhalant allergens), 62.5%, 92.6%, 78.9%, 84.7%, 83.3%(food allergens) and 81.5%, 94.4%, 91.5%, 87.5%, 89.0%(all allergens). Conclusion: Good to excellent qualitative agreement between ALLERG-O-LIQ and ImmunoCAP for the detection of specific and total IgE could be observed. The degree of agreement depended on the allergen and was higher in the group of inhalant allergens. The ALLERG-O-LIQ System represents a reliable test for the detection of specific and total IgE.     

检体诊断的系列研究与实践

针对目前我国医学教育存在的学生多、病人少的现状以及我校诊断学见习存在的弊端,在检体诊断教学中先后开展专科负责的教学方法、建立和完善典型阳性体征的病例档案及其在检体诊断教学中的应用、序贯教学方法等一系列研究,并分别与传统的教学方法进行比较,探讨新的教学方法与传统带教方法的教学效果差异。结果表明：上述教学方法既能较大程度缓解学生多病人少的矛盾,减少SARS或其他突发事件对诊断学教学的严重影响,也能促使学生重视基本技能训练,调动学生学习的积极性和主动性,提高检体诊断教学质量。