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21.
As part of a detailed study of limb defects and associated patterns of congenital malformations, cases with lower limb deficiencies were analysed separately. We identified a total of 130 cases with deficiencies of the lower limbs without defects of the upper limbs. This gives an incidence of 1.07/10,000 livebirths, or 1/9,337 for this group of limb defects. Most common were femur deficiencies and deficiencies of the foot. A preponderance of males was found in the group of transverse defects of the leg (fibula/tibia deficiencies) and central axis deficiencies, while females had significantly more often longitudinal tibia defects and preaxial ray defects. © 1993 Wiley-Liss, Inc. 相似文献
22.
Tetsuji Kai Yang Il Kim Hirokazu Kitamura Katsunori Kawano Seigo Kitano 《Journal of Hepato-Biliary-Pancreatic Surgery》1997,4(4):423-430
There is a growing body of evidence that the cytokine, tumor necrosis factor-α (TNF-ga), plays an important role in the development
of hepatic ischemia/reperfusion injury. We found that the immunosuppressants, cyclosporine-A (CsA), azathioprine, and FK506,
have protective effects on such injury. The purpose of the present study was to elucidate mechanisms involved in these beneficial
effects of the immunosuppressant, CsA, on liver injury following cold preservation and transplantation, with special reference
to the suppression of TNF-α release. Rat livers were stored in Euro-Collins solution (EC) at 4°C for 6h and orthotopically
transplanted. The animals allotted to two groups: group A (untreated controls) and group B (CsA pretreatment of recipients).
CsA (10 mg/kg, p.o.) was given for 3 consecutive days preoperatively. CsA pretreatment of the recipients significantly improved
the 2-week survival rate (0/6 for group A, 3/6 for group B;P<0.05) and this was associated with a significant decrease in serum TNF-α levels 2h posttransplantation (group A, 69.8±15.7
pg/ml; group B, 22.8±6.8; mean±SEM;n=12 each;P<0.05) and amelioration of sinusoidal endothelial injury, assessed by electron microscopy. Plasma endotoxin levels following
reperfusion of the grafts were not altered by the CsA therapy. Morphologically, CsA pretreatment of the recipients did not
alter activation of Kupffer cells. CsA pretreatment of the recipient aids in preventing cold preservation/reperfusion injury
of the liver graft, possibly by modulating effects of TNF-α. 相似文献
23.
东北地区风寒指数气候特征与冷习服锻炼日期的确定 总被引:2,自引:0,他引:2
应用中国东北48个站10年的逐日气象资料,分析了风寒指数(Vt)的候、月、旬、日平均值,据此,提出了各地可供冷习服锻炼的天数及可开始锻炼的日期等。研究结果在生物气候区划和指导部队耐寒锻炼等方面有重要作用,也有助于较精确的估算冷应激强度及寒冷环境对作业能力影响的预测。 相似文献
24.
本文运用模糊数学原理,对东台市1993年7月份市面上的全脂乳粉抽查监测结果进行卫生质量综合评价,结果令人满意,从而为乳粉卫生质量评比建立了客观有效的评价模型。 相似文献
25.
温经化瘀合剂临床疗效观察与研究 总被引:1,自引:0,他引:1
张华山 《浙江中医药大学学报》2004,28(1):27-30
目的:验证"温经化瘀舍剂"对妇女寒凝血瘀型痛经的治疗效果;方法:将符合中医诊断标准寒凝血瘀型痛经患者,随机分为2组,分别给予"温经化瘀合剂"和"痛经宁冲剂"进行治疗;结果:治疗组总有效率达95%,对照组总有效率80.5%,治疗组优于对照组,治疗组痊愈率48.3%,对照组痊愈率14.6%,治疗组明显优于对照组.实验动物无明显急性毒性反应,能减轻二甲苯引起的小鼠耳肿胀度,减少缩宫素所致大鼠扭体反应次数,和前列腺素E1所致小鼠扭体反应次数,对大鼠离体子宫有双向调节作用,证明"温经化瘀舍剂"具有镇痛、抗炎作用. 相似文献
26.
早期鼻饲生大黄粉防治重型颅脑损伤后上消化道出血的临床研究 总被引:6,自引:0,他引:6
目的研究重型颅脑损伤后早期鼻饲生大黄粉对防治上消化道出血的作用.方法选择GCS3~8分重型颅脑损伤患者90例,随机选45例(实验组)伤后早期(24~48h)鼻饲生大黄粉,另45例(对照组)未予生大黄粉治疗.所有患者其他治疗措施均基本相同.结果39例患者出现上消化道出血.其中实验组14例,有13例上消化道出血治愈,治愈时间(7.6±2.5)d;对照组25例,有16例上消化道出血治愈,治愈时间(13.4±3.3)d.实验组上消化道出血率和上消化道出血治愈平均时间均显著低于对照组(P<0.05),而上消化道出血治愈率显著高于对照组(P<0.05).结论早期鼻饲生大黄粉能有效防治重型颅脑损伤后并发上消化道出血,值得临床推广应用. 相似文献
27.
Abstract Laser Doppler flowmetry (LDF) was used to study the changes in pulpal blood flow (PBF) evoked by application of cold or heat to the palatinal surfaces of teeth 11 or 21 in nine young subjects. Switching from a thermode temperature of 33° to 5° G on average induced a slow decrease of PBF to about 80% of control, and also warming to 39°C evoked a small reduction in most subjects. Inter individual differences were large, however, and both cooling and warming sometimes triggered a rise in PBF. In contrast, skin blood flow, as recorded with LDF in the forearm, invariably rose during warming and fell during local cooling. The results suggested a more complex interaction between local and nervously mediated effects of moderate changes in temperature in the tooth pulp than skin, and that the previous held view of cold and heat decreasing and increasing PBF, respectively, is wrong. 相似文献
28.
The popularization and application of cold storage red blood cells or whole blood at −80 °C of the Rh(D) negative patients in surgical operation 总被引:2,自引:0,他引:2
Summary The efficiency of cold storage red blood cells (CSRBC) or whole blood at −80 °C used in 27 Rh(D) negative patients during
surgical operation was reported. The Rh(D) negative patients received the transfusion of CSRBC or whole blood stored at −80
°C for 180 to 360 days. The changes in the indexes, such as blood TB, DB, K+, Na+, BUN, Cr, urine protein (URPO), UOB, Hb, HCT, serum total protein, relative to hemolytic reaction and blood volume before
and after transfusion were observed. The results showed that after transfusion of CSRBC or whole blood 27 cases were negative
for urine protein and UOB, and the levels of BUN and Cr were normal (P>0.05). Blood TB, DB, Hb, and HCT were increased, while pH, blood K+ and blood Na+ was normal with the difference being not significant before and after operation (P>0.05). Plasma protein was decreased, but there was no significant difference before and after operation (P>0.05). It was suggested that CSRBC or whole blood at −80 °C could be safely infused to the Rh(D) negative patients without
side effects during the surgical operation.
YU Zhongqing, male, born in 1957, Technician in Charge 相似文献
29.
彩色多普勒超声诊断糖尿病下肢动脉病变的临床价值 总被引:3,自引:0,他引:3
目的 :研究彩色多普勒超声在糖尿病下肢动脉病变诊断中的应用。方法 :对临床上诊断为非胰岛素依赖型糖尿病 (NIDDM)患者发生下肢动脉病变的 6 2例进行彩色多普勒超声检查 ,并以 2 0例无糖尿病正常人作对照。结果 :6 2例NIDDM患者中阳性结果 4 0例 ,发病率 6 4 .5 2 %。正常对照组 2 0例 ,阳性结果 4例 ,发病率2 0 % ,下肢动脉病变程度与NIDDM组有显著性差异P <0 .0 1。结论 :彩色多普勒超声诊断糖尿病下肢动脉病变具有重要临床意义 ,且下肢动脉病变与NIDDM有密切相关性。 相似文献
30.
211例下肢长骨骨折带锁髓内钉固定的临床评价 总被引:5,自引:0,他引:5
目的 对211例下肢长骨骨折带锁髓内钉内固定治疗的临床结果进行评价。方法 用不扩髓带锁髓内钉为主要固定方法,对211例股骨、胫骨骨折进行手术复位内固定治疗,术后进行包括CPM在内的有序功能锻炼。结果 获得随访189例,时间4~26个月,平均9个月。全组病例获得骨性愈合,无骨不连发生,骨折延迟愈合7例,膝关节功能受限4例。按Johner-wruch标准:优158例,良22例,中9例,优良率95.2%。结论 带锁髓内钉是治疗下肢长骨骨折较好的方法,其适应证较以往有进一步的拓展,术中骨折复位与保存骨折块血供并重的理念是正确的。 相似文献