规则性肝段(叶)切除治疗肝内胆管结石并狭窄

目的探讨规则性肝段(叶)切除治疗肝内胆管结石并狭窄的临床疗效。方法48例肝胆管结石并狭窄患者,行左外叶切除19例,左半肝切除2例,左外叶+右后叶(或单纯Ⅵ、Ⅶ段)切除7例,右半肝(或单纯Ⅵ、Ⅶ段)切除20例;均行胆总管探查、T管引流术;行胆管空肠Roux-en-Y吻合术13例。结果术后胆管残石5例(10.4%),切口感染3例(6.2%),胆漏2例(4.2%)。随访41例(85.4%),2例肝内胆管结石复发,1例右上腹隐痛,其余随访结果优良。结论根据患者结石及狭窄的具体情况采用以肝段切除为主的手术方式是治疗肝内胆管结石并狭窄的有效手段。     

肝尾叶胆管结石的术中诊断与处理

目的 探讨肝尾叶胆管结石的术中诊断与手术处理方法。方法 回顾性总结19例尾叶胆管结石的诊疗经验。结果 全组均在术中明确诊断，右尾叶结石11例，左尾叶结石6例，双尾叶结石2例。合并左肝管结石2例，右肝管结石2例，左右肝管结石15例。10例合并尾叶胆管口狭窄者行尾叶胆管切开成形，肝胆管盆式Roux-en-Y吻合术；其余9例行左右肝管切开尾叶胆管取石，经胆总管T管或胆道气囊导管引流。无手术死亡，无并发症，术后15～18d经胆道造影，无结石残留，间歇夹管至术后21～28d后拔管。平均随访42．44（12～60）月，4例偶有腹痛，近远期疗效满意，无复发。结论 尾叶胆管结石术前易漏诊。术中诊查是发现尾叶胆管结石简便而有效的方法。充分显露、谨慎切开尾叶胆管口狭窄、取尽结石、通畅引流，是防止尾叶胆管结石残留的重要措施。     

兴城矿泉浴对胆石病患者胆囊排空功能的影响

目的　观察兴城故泉浴对胆石病的治疗作用。方法　经Ｂ 超证实的胆石病患者７６ 例,随机分为矿泉浴组和淡水浴组（ 各为３８ 例） 。矿泉为兴城矿泉,淡水为兴城饮用自来水,水温３８～４０ ℃,每日１ 次,每次３０ 分钟,共３０ 次。在受试前后于空腹和试餐后用Ｂ超测算空腹胆囊容积、胆囊最大排空率、最大排空时间及餐后６０ｍｉｎ 胆囊排空率。结果　矿泉浴前后胆囊最大排空率,空腹胆囊容积的差异不显著（Ｐ＞０ ．０５） ,最大排空时间及餐后６０ｍｉｎ 胆囊排空率的差异显著（Ｐ＜ ０．０５） ,治疗后症状改善。淡水浴前后胆囊最大排空率、最大排空时间、空腹胆囊容积及餐后６０ｍｉｎ 胆囊排空率的差异不明显（Ｐ＞ ０ ．０５） ,症状改善,但差异不显著（Ｐ＞ ０ ．０５） 。结论　兴城矿泉浴能改善胆石病患者的症状及胆囊排空功能。     

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors: A single‐institution experience

Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and life threatening. We report a retrospective analysis of 65 patients presenting to our institution from 1997 to 2008 with all forms of thrombotic microangiopathy. Therapeutic plasma exchange was a requirement for analysis and 65 patients were referred to our institution; 66% of patients were female and median age at presentation was 52 years. Bacterial infection was the most commonly identified etiologic factor and in the multivariate model was the only significant variable associated with survival outcome (odds ratio 5.1, 95% confidence interval, 1.2–21.7). As infection can be considered a common trigger event for thrombotic microangiopathy, patients with hepatobiliary sepsis may benefit from elective cholecystectomy. We conclude that bacterial infection frequently triggers TTP and other thrombotic microangiopathies in patients with preexisting risk factors and propose a model for the development of these syndromes. © J. Clin. Apheresis 2010. © 2010 Wiley‐Liss, Inc.     

Gallstone ileus: A rare cause of small intestine obstruction

Gallstone ileus is a very rare cause of mechanical bowel obstruction with often‐delayed presentation and nonspecific symptoms. Aerobilia is found in approximately 50% of patients with gallstone ileus.