头穴透刺对急性脑梗塞大鼠脑组织中β-EP与cAMP含量的相关性研究

目的 :探讨头穴透刺对急性脑梗塞大鼠脑组织中β EP( β Endorphin ,β内啡肽 )与cAMP(cyclicAMP ,环磷腺苷 )含量变化的相关性。方法 :用线栓法直接阻断大鼠大脑中动脉制作急性脑梗塞模型 ,采用放免技术 ,检测头穴透刺对急性脑梗塞大鼠脑组织中 β EP与cAMP含量的影响。结果 :头穴透刺后可使大鼠脑组织中cAMP的含量明显升高 ,使β EP含量明显降低而趋于正常值 ,两者之间呈显著负相关。结论 :头穴透刺可以调节脑组织中 β EP与cAMP的含量 ,改善梗死脑组织供血 ,这可能是针灸发挥治疗作用的重要机制之一     

针刺百会穴防治Norplant皮下埋植后出血性月经紊乱的临床观察

目的 :临床观察针刺单穴百会方法防治 Norplant导致的出血性月经紊乱。方法 :在要求埋植Norplant避孕的 3 90例无禁忌症的育龄妇女中 ,随机分组 ,实验观察组共 1 93例对象 ,于埋植前针刺百会穴并留针 3 0 min;空白对照组共 1 97例对象 ,不给予针刺 ,其它常规处置两组相同 ,进行预防效果观察。对空白对照组中埋植 Norplant后发生较严重月经紊乱的 1 1 9例对象 ,包括 1 4例月经稀发和闭经 ,再次随机分组 :针刺治疗组 5 9例 ,于发病后仅给予每日 1次连续 3天的针刺 ;另 6 0例仅作常规药物治疗。结果 :(1 )预防效果 :一年内月经紊乱发生率对照组为 6 0 .4%,研究组为 3 5 .2 %(χ2 =2 4 .75 ,P<0 .0 1 ) ,其中研究组月经频发、经期延长和点滴出血发生率为 2 9.0 %,对照组为 5 3 .2 %(χ2 =2 2 .73 ,P<0 .0 1 ) ;Norplant一年连续使用率对照组为 90 .9%,研究组为 98.4%(χ2 =1 1 .0 0 ,P<0 .0 1 )。(2 )治疗效果 :针刺治疗组 79.7%的病例月经基本恢复 ;常规药物治疗组月经基本恢复为 48.3 %(χ2 =1 2 .6 5 ,P<0 .0 1 )。结论 :提示针刺防治 Norplant导致的出血性月经紊乱有较明确的临床效果和可行性 ,值得深入研究。     

Three Clinical Methods of Circulatory Assistance

Three clinical methods of circulatory assistance are described: intraaortic balloon counterpulsation, left ventricular bypass using a roller pump, and the artificial ventricle. All three methods have hemodynamic effectiveness. The first method is indicated in cases of widespread cardiosclerosis and pronounced coronary insufficiency and may be contraindicated in pathology of the valvular apparatus. The second method demonstrated a temporary positive effect in patients in whom it was not possible to discontinue artificial circulation. The artificial ventricle is useful in treating patients with cardiogenic shock following cardiac surgery.     

缪刺考

At present, most physicians hold that Miu Ci is "left and right cross collateral prick-ing",but it does not conform to the original meaning of "Suwen·Miucilunpian"(Plain Questions ·Trea-tise on Miu Ci). Miucilanpian holds that Miu Ci is the extension and perfection of Ju Ci (contralateral me-ridian needling), which mainly pricks the collateral but is not limited to the collateral, as it also pricks the acupuncture point. As for the "left and right cross" point selection, it is one step in the procedure of the treatment in the process of contralateral collateral needling instead of being a principle.     

Transaortic inflow and outflow cannula for centrifugal mechanical assistance

A specific cannula allowing single site transaortic inflow and outflow cannulation for centrifugal assist devices is described. The cannula is inserted through a straight 18 mm collagen coated Dacron tube anastomosed to the anterior aspect of the ascending aorta. The inflow conduit of the cannula is positioned into the left ventricle through the aortic valve, and the end hole of the outflow conduit is positioned in the ascending aorta. The cannula was evaluated in vivo in 3 adult pigs by the institution of a centrifugal pump for left ventricular support. Optimal flow varied between 5 and 6 L/min and mean aortic pressure between 55 and 70 mm Hg throughout the 3 days of left ventricular support. Recently, we employed this cannula in a patient who was not able to be weaned from cardiopulmonary bypass for the institution of left ventricular support using a centrifugal pump. The cannula provided effective inflow and outflow drainage with an optimal flow of 5.2 L/min throughout the 72 h of support. The patient was successfully weaned from support on the fourth postoperative day. This rational transaortic approach of cannulation using this specific cannula is a refined implantation technique which allows direct left ventricular inflow drainage, reduces the time of implantation, spares left ventricular myocardium, avoids bleeding that is sometimes encountered at other cannulation sites, and avoids compression of the heart by cannulas.     

Biodesign of a skeletal muscle flap as a model for cardiac assistance

In using autologous muscles for cardiac assistance, it is crucial to reduce ischemia-reperfusion injury in the surgically traumatized skeletal muscle. In adult sheep, we developed a simple model of surgically designed 2 latissimus dorsi muscle leaflets by modifying the vascular supply to these leaflets. Three pockets with graded injury were established, and muscle morphology and vascular remodeling were monitored in 3 experimental groups: muscle leaflets without any treatment (Group 1, n = 6) that served as controls; muscle leaflets integrated with a fibrin interlayer (Group 2, n = 6); and leaflets integrated with fibrin and entrapped pyrrolostatin (Group 3, n = 6). We applied the fibrinogen and thrombin solutions, which polymerize to form a three-dimensional meshwork joining the tissues, creating a provisional matrix for angiogenesis, and acting as a delivery depot for agents aimed at minimizing ischemia-reperfusion lesion formation. After 2 months, the muscle leaflets biointegrated with the fibrin interface showed none of the signs of necrosis or ischemia-reperfusion lesions seen in the controls. Although no angiogenic factors were incorporated, the fibrin interlayer rapidly (<2 weeks) became a densely vascularized tissue replete with a voluminous capillary network. In contrast, controls showed poor bonding between the tissues, muscle fiber deterioration, and a compromised vascular network. Muscle structure was best preserved and angiogenesis was greatest when pyrrolostatin, a free radical scavenger, was added to the fibrin meshwork to reduce damage caused by overproduction of free radicals. This newly designed model will be useful to study many current approaches in cardiovascular biology, from pharmaceuticals to gene therapy, which might prove advantageous in muscle-designed cardiac assistance.     

OBSERVATION ON THE THERAPEUTIC EFFECT OF CT—AIDED SURROUNDING NEEDLING IN THE TREATMENT OF ISCHEMIC STROKE AND CHANGES OF PLASMA CATECHOLAMINE LEVEL

Ｓｔｒｏｋｅｉｓａｃｏｍｍｏｎｌｙｍｅｔａｎｄｆｒｅｑｕｅｎｔｌｙｏｃｃｕｒｒｉｎｇｄｉｓｅａｓｅｉｎｃｌｉｎｉｃ ,ａｎｄｉｓｏｎｅｏｆｔｈｅｄｉｓ ｅａｓｅｓｗｉｔｈｈｉｇｈｅｒｍｏｒｂｉｄｉｔｙ ,ｈｉｇｈｅｒｍａｉｍｒａｔｅａｎｄｈｉｇｈｅｒｄｅａｔｈｒａｔｅｉｎｔｈｅｗｏｒｌｄ .Ｉｎｏｒｄｅｒｔｏｓｅａｒｃｈｆｏｒｍｏｒｅｅｆｆｅｃｔｉｖｅａｃｕｐｕｎｃｔｕｒｅｔｈｅｒａｐｙｆｏｒｔｒｅａｔｍｅｎｔｏｆｉｓｃｈｅｍｉｃｓｔｒｏｋｅ ,ｔｈｉｓｐａｐｅｒｓｕｍｓｕｐｒｅｓｕｌｔｓｏｆＣＴ ａｉｄ…     

透刺法治疗第三腰椎横突综合征66例

目的　观察透刺法治疗第三腰椎横突综合征的疗效。方法　采用外关透内关、腰 2 透腰 4 横突的透刺法治疗第三腰椎横突综合征 6 6例 ,并与常规针刺方法治疗 4 5例作对照。结果与结论　治疗组痊愈率与总有效率分别为 6 6 .7%和 95 .5 % ,对照组为 4 6 .7和 71.1% ,表明治疗组疗效优于对照组 (P<0 .0 5 )。     

大学生心理问题求助方式的调查分析

目的调查大学生解决心理问题的理想求助方式,为高校更好开展心理健康教育提供依据。方法采用自设的大学生心理问题求助方式调查表,随机抽取泰山医学院1 536名在校大学生进行调查。结果大学生解决心理问题的方式以知心朋友倾诉、阅读疗法、音乐疗法、文体活动等自助解决为主,求助心理医生、辅导员为次。结论高校应加强对同伴辅导法、阅读疗法、音乐疗法等大学生喜闻乐见的心理健康教育方法的研究。     

浅刺多针法对单纯性肥胖患者的三围及脂质代谢的影响

[目的]观察浅刺多针法治疗单纯性肥胖症的临床疗效,及对单纯性肥胖患者的三围、脂质代谢的影响。[方法]按诊断标准纳入病例20例,采用浅刺多针法进行治疗,每天1次,20次为观察疗程,对所得相关资料进行分析。[结果]经20次治疗,单纯性肥胖患者的体重、腰围、血清TC、TG、LDL等均有明显改变,具有统计学意义(P<0.05)。[结论]浅刺多针法对单纯性肥胖有较好的临床疗效。