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31.
Madrazo Z Silvio-Estaba L Secanella L García-Barrasa A Aranda H Golda T Biondo S Rafecas A 《Cirugía espa?ola》2007,82(3):139-145
Smuggling of illicit drugs by concealing them within the human body (body packer) is a medical-legal issue that has increased in the last few decades. Physicians, especially those working in the emergency department, should be familiar with the diagnostic and therapeutic management -usually conservative management- of this type of patient and their possible complications. The present article reviews the general concepts and physiopathology associated with transport of packages in the digestive tract and describes the experience of a referral hospital with a protocol specifically designed for these patients. 相似文献
32.
目的 利用背景抑制弥散加权成像(DWIBS)定量测量子宫内膜癌肿瘤组织的信号强度和表观弥散系数(ADC)值,探讨肿瘤组织ADC值与增殖细胞核抗原(PCNA)表达情况的相关性.方法 收集具有完整磁共振资料和临床资料并经病理学证实的子宫内膜癌患者33例.分别行女性盆腔常规磁共振及DWIBS检查,测量子宫内膜癌肿瘤组织的信号强度和ADC值,并对不同病理分级子宫内膜癌肿瘤组织的信号强度、ADC值进行分析;免疫组织化学法测定PCNA表达情况,并与肿瘤组织ADC值进行相关性分析.结果子宫内膜癌肿瘤组织的平均信号强度和ADC值分别为(172.37±14.12),(0.94±0.17) mm2/s;高、中分化子宫内膜癌肿瘤组织的ADC值之间存在统计学差异(P<0.05),但信号强度之间无统计学差异(P>0.05):子宫内膜癌肿瘤组织的ADC值与其PCNA表达情况呈负相关(r=-0.81,P <0.05).结论 子宫内膜癌肿瘤组织ADC值定量测量对其病理分级有重要临床价值,同时可在一定程度上提示肿瘤组织的PCNA表达情况. 相似文献
33.
34.
López L Arai K Giménez E Jiménez M Pascuzo C Rodríguez-Bonfante C Bonfante-Cabarcas R 《Revista espa?ola de cardiología》2006,59(1):50-56
INTRODUCTION AND OBJECTIVES: Chagas disease is the most common cause of myocarditis in Latin America, including Venezuela. Some 25% of patients progress to chronic chagasic cardiomyopathy, which is characterized by heart failure and arrhythmias. The serum levels of C-reactive protein (CRP) and interleukin-6 (IL-6) have prognostic value in non-chagasic cardiopathy. The goal of this study was to investigate the relationship between the serum levels of CRP and IL-6 and the developmental stage of Chagas disease. PATIENTS AND METHOD: The study included 64 Chagas disease patients (34 female and 30 male; age 62.2 [1.7] years) and 20 healthy individuals (10 of each sex; age 50.4 [2.7] years). Clinical investigations included echocardiography and measurement of CRP and IL-6 serum levels using ELISAs. Chagas disease patients were graded according to Carrasco et al 1994 classification. Patients with ischemic cardiopathy, liver disease, autoimmune disease, a systemic inflammatory condition, immunosuppression, cancer, pericarditis, or endocarditis were excluded. RESULTS: Multiple regression analysis demonstrated an association between Chagas disease developmental stage and the serum IL-6 level. The serum CRP level increased during only the most advanced phase of the disease. In addition, a high left ventricular mass index was associated with a high IL-6 level and male sex. CONCLUSIONS: IL-6 and CRP serum levels could be of prognostic value in assessing Chagas disease progression because there are significant correlations between elevated levels and the deterioration of cardiac function. 相似文献
35.
Thymic Function-Related Markers Within the Thymus and Peripheral Blood: Are They Comparable? 总被引:1,自引:0,他引:1
Arellano MV Ordóñez A Ruiz-Mateos E Leal-Noval SR Molina-Pinelo S Hernández A Vallejo A Hinojosa R Leal M 《Journal of clinical immunology》2006,26(1):96-100
The thymus involutes with age and its functionality has traditionally been assumed to be limited early in life. However, some studies have demonstrated that thymic function persists in adults. In humans, since it is difficult to obtain thymic samples from healthy individuals, indirect parameters have been used to study the thymic function. The aim of this study was to compare thymic function parameters within both the thymus and peripheral blood mononuclear cells from thirty-three patients who underwent cardiac surgery, as well as to relate these parameters with aging. The proportion of peripheral naïve T cells and intrathymic T cell differentiation stages, as well as peripheral and intrathymic TREC levels were analysed. We demonstrated that thymopoyesis persists in the healthy elderly since all T cell differentiation stages were found within the thymus. Among the studied parameters, peripheral TREC levels are found to be a good thymic function marker since they correlated with age. In healthy individuals, peripheral TREC levels are a good reflect of thymic function as demonstrated by their correlation with intrathymic TREC values. 相似文献
36.
《Reumatología clinica》2022,18(3):184-185
We present the case of a 36-year-old woman with diffuse idiopathic skeletal hyperostosis especially at cervical spine since she was 29 years old. The only relevant feature was the use of isotretinoin at regular doses in the past for severe acne. 相似文献
37.
Li Huanan Wang Jingui Zhang Wei Zhao Na Hai Xinhua Sun Shiquan Sun Qing Han Yihao Zhang Runchen Ma Fei 《中医杂志(英文版)》2017,37(6):819-826
Objective
To evaluate the effect of the traditional Chinese procedure abdominal Tuina (AT) on chronic fatigue syndrome (CFS).Methods
This randomized, single assessor-blinded clinical trial was carried out from May 2014 to April 2015. Eighty participants in the trial were divided randomly into two groups: experimental group and control. The experimental group (40 cases) was treated by AT and the control group (40 cases) by acupuncture. Each treatment was conducted once a day, 5 d for one course, at an interval of 2 d between each course. The whole treatment course lasted for 4 weeks. To ascertain the effect of AT and acupuncture, Fatigue Scale-14 (FS-14), Self-rating Anxiety Scale (SAS) and Hamilton Rating Scale for Depression (HAMD) scores were used before and after treatment. Patients were followed up for 3 months after treatment.Results
After treatment for 4 weeks, 77 patients (39 cases in the experimental group and 38 cases in the control group) completed the trial. The FS-14, SAS and HAMD scores decreased (P < 0.05) significantly compared with those before treatment in both groups. The FS-14 and HAMD (P < 0.05) scores in the experimental group were much lower than those in the control group. The difference in SAS scores between the two groups was not significant. In the final follow-up, CFS in two cases in the experimental group and three in the control group recurred, but the difference was not significant. The scores for the FS-14, SAS and HAMD in the experimental group were superior to those of the control group, and the difference was significant (P < 0.05). No serious adverse events and few adverse events were observed.Conclusion
AT elicited a more efficacious effect than acupuncture alone on CFS. 相似文献38.
Fournier JA Delgado-Pecellín C Cayuela A Cabezón S Mendoza MD 《Revista espa?ola de cardiología》2008,61(3):313-316
The significance of the high-sensitivity C-reactive protein (hs-CRP) level in percutaneous coronary interventions (PCIs) is unclear. Troponin-T and hs-CRP levels were measured before PCI, after stenting, and 8 h, 24 h, and 30 days after the procedure in 68 consecutive patients who received bare-metal stents. The study endpoints were death, nonfatal myocardial infarction, and the need for revascularization. The mean follow-up time after PCI was 16.6 months. Patients who experienced an event had higher hs-CRP levels 24 h (P=.05) and 30 days (P< .02) after stenting. The area under the receiver operating characteristic (ROC) curve at 30 days had the highest sensitivity (i.e., 80%) and specificity (i.e., 72%) for predicting an event. The 12-month event-free survival rate (Kaplan-Meier) was greater when the hs-CRP level at 30 days was < or =2.5 mg/L than when it was above this value (P=.04). Consequently, measuring the hs-CRP level 30 days after stenting may be useful for predicting late events. 相似文献
39.
《Actas dermo-sifiliográficas》2023,114(2):T125-T131
Cocaine and some of its main adulterants, such as levamisole, can cause multiple cutaneous and mucosal manifestations, including ischemic complications, neutrophilic dermatoses, midline destructive lesions, and vasculitis associated with antineutrophil cytoplasmic antibodies (ANCAs). Striking systemic symptoms are generally not seen. In all these conditions, positive test results may be observed for antinuclear antibodies, antiphospholipid antibodies, and various ANCAs, sometimes with characteristic staining patterns. Histology typically shows vascular changes, such as leukocytoclastic vasculitis, necrotizing vasculitis, and thrombi. We review the clinical, serologic, and histologic features of cutaneous and mucosal conditions associated with the use of cocaine and also look at pathophysiologic mechanisms, differential diagnoses, and treatments. 相似文献
40.
Rocío Aller Conrado Fernández-Rodríguez Oreste lo Iacono Rafael Bañares Javier Abad José Antonio Carrión Carmelo García-Monzón Joan Caballería Marina Berenguer Manuel Rodríguez-Perálvarez José López Miranda Eduardo Vilar-Gómez Javier Crespo Miren García-Cortés María Reig José María Navarro Rocío Gallego Joan Genescà Manuel Romero-Gómez 《Gastroenterologia y hepatologia》2018,41(5):328-349