全文获取类型
收费全文 | 159710篇 |
免费 | 10315篇 |
国内免费 | 2070篇 |
专业分类
耳鼻咽喉 | 3257篇 |
儿科学 | 1583篇 |
妇产科学 | 2047篇 |
基础医学 | 3877篇 |
口腔科学 | 3632篇 |
临床医学 | 44817篇 |
内科学 | 11717篇 |
皮肤病学 | 1054篇 |
神经病学 | 3972篇 |
特种医学 | 2273篇 |
外国民族医学 | 21篇 |
外科学 | 31358篇 |
综合类 | 23233篇 |
现状与发展 | 6篇 |
一般理论 | 7篇 |
预防医学 | 11316篇 |
眼科学 | 4912篇 |
药学 | 8799篇 |
591篇 | |
中国医学 | 7155篇 |
肿瘤学 | 6468篇 |
出版年
2024年 | 541篇 |
2023年 | 3424篇 |
2022年 | 5106篇 |
2021年 | 6885篇 |
2020年 | 7833篇 |
2019年 | 6299篇 |
2018年 | 5595篇 |
2017年 | 5711篇 |
2016年 | 6238篇 |
2015年 | 6146篇 |
2014年 | 13186篇 |
2013年 | 11302篇 |
2012年 | 10635篇 |
2011年 | 11401篇 |
2010年 | 9592篇 |
2009年 | 7823篇 |
2008年 | 7062篇 |
2007年 | 7261篇 |
2006年 | 6250篇 |
2005年 | 5324篇 |
2004年 | 4214篇 |
2003年 | 3388篇 |
2002年 | 2501篇 |
2001年 | 2389篇 |
2000年 | 2019篇 |
1999年 | 1749篇 |
1998年 | 1384篇 |
1997年 | 1208篇 |
1996年 | 887篇 |
1995年 | 719篇 |
1994年 | 620篇 |
1993年 | 479篇 |
1992年 | 420篇 |
1991年 | 376篇 |
1990年 | 272篇 |
1989年 | 233篇 |
1988年 | 247篇 |
1987年 | 226篇 |
1985年 | 564篇 |
1984年 | 624篇 |
1983年 | 426篇 |
1982年 | 467篇 |
1981年 | 492篇 |
1980年 | 421篇 |
1979年 | 399篇 |
1978年 | 354篇 |
1977年 | 225篇 |
1976年 | 285篇 |
1975年 | 263篇 |
1973年 | 219篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
Early experience with laparoscopic abdominoperineal resection 总被引:4,自引:0,他引:4
Background: Laparoscopic abdominoperineal resection (LAPR) has not been fully evaluated as a technique in the treatment of rectal and
anal cancer or inflammatory bowel disease. The purpose of our study was to evaluate the early experience with laparoscopic
abdominoperineal resection at Washington University Medical Center.
Methods: A prospective analysis was performed on the first 21 patients undergoing the procedure at Washington University Medical Center.
Indications for surgery included rectal cancer (14 patients), anal squamous cell cancer (four patients), inflammatory bowel
disease (two patients), and anal melanoma (one patient).
Results: The procedure was converted to open procedure in four patients (19%). The mean (±SEM) operative time and blood loss for completed
and converted LAPR were 239 ± 11 min and 424 ± 43 ml, respectively. Postoperative hematocrit dropped a mean of 8.3% ± 1.2%
SEM; five patients required blood transfusion (24%). Wound complication occurred in four patients (19%; three perineal, one
trocar site). Bowel function returned after a mean of 3 days, and mean postoperative hospital stay for the completed LAPR
group was 5 days. Mild pain was experienced by 81% of patients (17/21) while 19% (4/21) noted moderate pain, usually of the
perineal wound. The mean duration of patient-controlled analgesia use was 2 days. During the 1–44-month follow-up, six patients
(29%) died from cancer (stage III or IV at operation) and only one patient developed local recurrence in the pelvis (5%).
There were no trocar-site implants of cancer. Furthermore, there was no relationship between prior abdominal operations, the
amount of blood loss, postoperative drop of hematocrit, or blood transfusion requirement and the length of hospitalization
or complication rates.
Conclusion: Laparoscopic abdominoperineal resection is a feasible alternative to the conventional open technique in both cancer and colitis
patients.
Received: 23 April 1996/Accepted: 8 July 1996 相似文献
62.
Background: Increasingly larger series of laparoscopic fundoplications (LF) are being reported. A well-documented advantage of the laparoscopic
approach is shortened hospital stay. Most centers report typical lengths of stay (LOS) for LF of 2–3 days. Our success with
LF with a LOS of 1 day led to an attempt at performing LF on an ambulatory basis.
Methods: Sixty-one consecutive patients with appropriate criteria for LF underwent surgery at our institution. Patients were counseled
by the authors as to the usual postop course and progression of diet. All patients received preemptive analgesia (PEA) consisting
of perioperative ketorolac and preincisional local infiltration with bupivicaine. Anesthetic management included induction
with propofol, high-dose inhalational anesthetics, minimizing administration of parenteral narcotics, and avoidance of reversal
of neuromuscular blockade. Immediate postop pain management included parenteral ketorolac and oral hydro- or oxycodone. All
patients were given oral fluids and soft solids after transfer from the recovery room to the postoperative observation unit.
Two patients were excluded from ambulatory consideration due to excessive driving distance from our hospital. Another two
were hospitalized for observation after experiencing intraoperative technical problems.
Results: Of 57 patients in whom same-day discharge was attempted, there were three failures requiring overnight hospitalization: All
were due to pain and nausea; one patient also suffered transient urinary retention. There were no adverse outcomes related
to early discharge, and there were no readmissions. One patient returned to the emergency room after delayed development of
urinary retention. Median time from conclusion of operation to discharge was less than 5 h. No patients expressed dissatisfaction
with early discharge on follow-up interview.
Conclusions: LF can be safely performed as an ambulatory procedure. Analgesic and anesthetic management should be tailored to minimize
nausea and provide adequate pain control.
Received: 1 April 1996/Accepted: 29 May 1997 相似文献
63.
64.
65.
P. J. Donald 《European archives of oto-rhino-laryngology》2007,264(7):713-717
The purpose of this paper is to detail the contraindications for surgery, with curative intent for those patients who suffer
from a head and neck malignancy that invades the intracranial space. This is based on a 30-year experience of over 250 patients.
The most important contraindications are anatomical. Surgery is not done if the following structures are invaded: brain stem,
eloquent portions of the cerebrum, superior sagittal sinus, both internal carotid arteries, both cavernous sinuses and certain
vital bridging veins. Certain tumor factors are absolute but are occasionally relative contraindications: such as distant
metastatic disease especially if multiple and at multiple anatomic sites. Some tumors that behave in a particularly virulent
fashion that defy complete resection but are often difficult to predict preoperatively. Lack of patient medical fitness or
absence of patient commitment to the operative procedure is make-up two serious contraindications to surgery.
Presented at the 77th Annual Meeting of the German Society for Oto-Rhino-Laryngology, Head and Neck Surgery, 24–28 May 2006,
Mannheim, Germany. 相似文献
66.
Intra-articular fractures of the proximal tibia present a wide spectrum of injury patterns with associated soft tissue injury. The last two decades have seen the techniques of management evolve from extensive open reduction and rigid internal fixation to arthroscopy-assisted minimal invasive surgery (MIS) and biologically benign internal fixation. The ultimate aim is to prevent the occurrence of late degenerative arthritis. This could be achieved in selected patients using minimal invasive surgery, which offers the advantages of better visualisation and management of intra-articular soft tissue injuries, confirmation of fracture reduction viewed from the joint surface, faster rehabilitation and fewer wound complications. 相似文献
67.
Louise Rose MN Adult Ed Cert BN ICU Cert Dip Nurs Marie F. Gerdtz RN BN AE Cert GDAET PhD 《Australasian emergency nursing journal : AENJ》2007,10(1):26-29
The use of mechanical ventilation in the Emergency Department requires adequate resources in order to maintain patient safety and avoid potential risks. Moreover, developments in technology require increased knowledge of mechanical ventilation techniques to address the complexity of decision-making involved. Organisational issues and system factors have the potential to negatively impact on the ability of the emergency service to provide optimum care to patients receiving mechanical ventilation. These issues include staffing and skill-mix, demand on emergency services, role-delineation, scope of practice, and current mechanisms for monitoring of quality and safety. Furthermore, in response to advances in ventilator technology, current education programs for both nursing and medical staff require review to ensure that they provide comprehensive information about the types of ventilation techniques now available and the relative risks and benefits associated with their application.This article is the second in a two-part series and explores the educational and organisational factors that impact upon safety and quality of care delivered to patients receiving mechanical ventilation in the emergency department. Recommendations for future policy development, curriculum review and reporting mechanisms to support further research in the application of mechanical ventilation in the emergency department are made. 相似文献
68.
The effect of laser refractive surgery on the on-field performance of professional baseball players.
BACKGROUND: The aim of this study was to determine the effect of laser refractive surgery on the offensive performance of professional baseball players. METHODS: Extensive search of the public media was conducted to determine which major league baseball players had undergone laser refractive surgery and when the procedure was performed. Baseball performance data were then used to determine presurgery and postsurgery baseball performance averages. A total of 17 position players were identified; however, 5 of these players were not considered in the analysis owing to insufficient playing experience either before or after the laser procedure. RESULTS: No statistically significant or practically significant difference was found between the presurgery and postsurgery means on either on-base percentage (P = 0.31), batting average (P = 0.39), slugging percentage (P = 0.66) or on-base plus slugging (OPS; P = 0.997) of major league baseball players. CONCLUSIONS: These preliminary findings suggest that professional baseball players should not expect a laser refractive surgical procedure to significantly improve their offensive baseball performance, despite the elimination of glasses or contact lens wear. 相似文献
69.
C. Constanzo I. T. Jackson C. McEwan J. M. Self 《European journal of plastic surgery》1987,9(4):137-140
Summary The clinical features and histological appearance of desmoplastic malignant melanoma are presented. Aggressive surgical management and close follow-up are mandatory if this highly aggressive tumor is to be controlled. Despite this, the prognosis is poor. 相似文献
70.
Abstract: The development of a teaching package for nurse educators on drug and alcohol problems is described and the contents of its 16 modules outlined. 相似文献