月经前后手三阴经原穴伏安特性

目的:观察健康女性月经前后穴位伏安特性的变化规律,研究穴位伏安特性与人体气血变化的关系,创建气血变化定量研究新方法。方法:应用自制的穴位伏安特性计算机检测系统对健康女性月经前、月经时及月经后手三阴经原穴太渊、大陵、神门进行伏安特性检测。结果:月经前后太渊、大陵、神门穴均有部分扫描点电阻发生了明显的变化,以大陵最为明显、太渊次之、神门最不明显,差异均有统计学意义。在三个穴位所有电阻发生明显变化的扫描点中,穴位电阻随月经进程变大的比率为70.6%。结论:穴位伏安特性随月经的进程而变化,这种变化具有穴位特异性。穴位电阻随月经进程而变大,这可能与月经后机体血量减少有关。穴位伏安特性有可能作为研究气血变化的定量指标。     

一种新的用于图像稳定的特征点检测方法

二维特征点的检测和提取是进行图像配准、目标识别和运动匹配的关键技术。针对不同的后继任务, 检测和提取的方法也有所不同。在多目标跟踪和识别技术中, 图像稳定是必要的处理过程, 而如何找到对应的特征点则是其难点所在。本文基于Gabor小波变换, 提出了一种新的分散型自适应策略。该方法能够迅速、有效地在前后两帧图像中找出可能的对应特征点, 以便进行特征点匹配, 从而完成图像稳定。实验表明, 本文方法检测到的特征点能够确切代表两帧图像间的运动情况, 从而为图像稳定提供了可靠的基础。     

电针夹脊穴治疗神经根型颈椎病疗效观察

目的:观察对比电针夹脊穴与电针循经取穴治疗神经根型颈椎病的临床疗效,并探讨电针夹脊穴的作用机理.方法:120例神经根颈椎病患者,随机分为两个治疗组,60例采用电针夹脊穴治疗,60例采用电针循经取穴治疗.进行疗效对比分析.结果:电针夹脊穴治疗相对循经取穴治疗来说,有更好的治疗效果和简单的取穴方法.结论:电针夹脊穴治疗神经根型颈椎病疗效确切,安全可靠,操作简单,便于临床推广应用.     

Review of Health Source – Consumer Edition

The pace of publication in consumer health continues unabated. EBSCO’s Health Source – Consumer Edition provides one of the few indexing and abstracting services to assist users looking to these types of publications for help with their health questions. This column provides a guide to some of the database features and resources. While the reading level for some of its indexed sources is relatively high, and the collection of books is dated at present. Health Source – Consumer Edition remains a valuable tool in the consumer health librarian’s toolkit.     

How cost effective is switching universal vaccination from PCV10 to PCV13? A case study from a developing country

BackgroundChildren immunization with pneumococcal conjugate vaccine (PCV) had profound public health effects across the globe. Colombian adopted PCV10 universal vaccination, but PCV incremental impact need to be revalued. The objective of this analysis was to estimate the cost-effectiveness of switch to PCV13 versus continue PCV10 in Colombian children.MethodsA complete economic analysis was carried-out assessing potential epidemiological and economic impact of switching from PCV10 to PCV13. Epidemiological information on PCV10 impact was obtained from lab-based epidemiological surveillance on pneumococcal isolates at the Colombian National Institute of Health. Economic inputs were extracted from the literature. Incremental PCV13 effectiveness was based in additional serotypes included. Comparisons among alternatives were evaluated with the Incremental Cost-Effectiveness Ratio (ICER) at a willingness to pay of one GDP per capita (USD$ 6631) per Year of Live Saved (YLS). All costs were reported in 2014USD. Deterministic and probabilistic sensitivity analyses were performed, and 95% confidence interval reported.ResultsAfter four years using PCV10 for universal vaccination on children the Colombian health surveillance system showed a relative increment on non PCV10 isolates. To change from PCV10 to PCV13 would avoid 587 (CI95% −49–1008) ambulatory Rx community-acquired pneumoniae (CAP), 1622 (CI95% 591–2343) Inpatient RxCAP, 10 (CI 95% 6–11) pneumococcal meningitis, and 79 (CI95% 76–98) deaths. ICER per YLS was USD$ 2319 (CI95% Dominated – USD$ 4225) for Keep-PCV10 and USD$ 1771 (CI95% USD$ 1285–9884) for Switch-to PCV13. In spite of its cost-effectiveness Keep-PCV10 is an extended dominated alternative and Switch-to PCV13 would be preferred. Results are robust to parameters changes in the sensitivity analyses.ConclusionA national immunization strategy based in Switch-to PCV13 was found to be good value for money and prevent additional burden of pneumococcal disease saving additional treatment costs, when compared with to Keep-PCV10 in Colombia, however additional criteria to decision making must be taken into account.     

An Evaluation of the Nutrition Services for the Elderly

No abstract available for this article.     

医院制剂复方甘草口服溶液质量回顾分析

目的 对医院制剂复方甘草口服溶液进行质量回顾分析,及时发现并纠正生产过程的不良趋势,保证制剂质量.方法 采用单值-移动极差控制图法和风险级别判断矩阵对中国人民解放军联勤保障部队第九〇〇医院近五年生产的复方甘草口服溶液质量进行分析.结果 2014年6月至2019年6月,该院生产的30批次复方甘草口服溶液质量符合法定标准,控制图显示该品种生产工艺较稳定,针对复方甘草口服溶液中愈创木酚甘油醚含量波动较大的问题进行风险分析并采取了有效措施控制风险.结论 控制图分析结合风险管理,更有利于我院持续、稳定地生产出质量优异的复方甘草口服溶液.     

Pinging the brain with transcranial magnetic stimulation reveals cortical reactivity in time and space

BackgroundSingle-pulse transcranial magnetic stimulation (TMS) elicits an evoked electroencephalography (EEG) potential (TMS-evoked potential, TEP), which is interpreted as direct evidence of cortical reactivity to TMS. Thus, combining TMS with EEG can be used to investigate the mechanism underlying brain network engagement in TMS treatment paradigms. However, controversy remains regarding whether TEP is a genuine marker of TMS-induced cortical reactivity or if it is confounded by responses to peripheral somatosensory and auditory inputs. Resolving this controversy is of great significance for the field and will validate TMS as a tool to probe networks of interest in cognitive and clinical neuroscience.ObjectiveHere, we delineated the cortical origin of TEP by spatially and temporally localizing successive TEP components, and modulating them with transcranial direct current stimulation (tDCS) to investigate cortical reactivity elicited by single-pulse TMS and its causal relationship with cortical excitability.MethodsWe recruited 18 healthy participants in a double-blind, cross-over, sham-controlled design. We collected motor-evoked potentials (MEPs) and TEPs elicited by suprathreshold single-pulse TMS targeting the left primary motor cortex (M1). To causally test cortical and corticospinal excitability, we applied tDCS to the left M1.ResultsWe found that the earliest TEP component (P25) was localized to the left M1. The following TEP components (N45 and P60) were largely localized to the primary somatosensory cortex, which may reflect afferent input by hand-muscle twitches. The later TEP components (N100, P180, and N280) were largely localized to the auditory cortex. As hypothesized, tDCS selectively modulated cortical and corticospinal excitability by modulating the pre-stimulus mu-rhythm oscillatory power.ConclusionTogether, our findings provide causal evidence that the early TEP components reflect cortical reactivity to TMS.     

Clinical reasoning for manual therapy management of tension type and cervicogenic headache

In recent years, there has been an increasing knowledge in the pathogenesis and better management of chronic headaches. Current scientific evidence supports the role of manual therapies in the management of tension type and cervicogenic headache, but the results are still conflicting. These inconsistent results can be related to the fact that maybe not all manual therapies are appropriate for all types of headaches; or maybe not all patients with headache will benefit from manual therapies. There are preliminary data suggesting that patients with a lower degree of sensitization will benefit to a greater extent from manual therapies, although more studies are needed. In fact, there is evidence demonstrating the presence of peripheral and central sensitization in chronic headaches, particularly in tension type. Clinical management of patients with headache needs to extend beyond local tissue-based pathology, to incorporate strategies directed at normalizing central nervous system sensitivity. In such a scenario, this paper exposes some examples of manual therapies for tension type and cervicogenic headache, based on a nociceptive pain rationale, for modulating central nervous system hypersensitivity: trigger point therapy, joint mobilization, joint manipulation, exercise, and cognitive pain approaches.