Sleep Questionnaire Versus Sleep Diary: Which Measure Is Better?

One questionnaire about a typical week's sleep is more convenient than asking individuals to complete daily sleep diaries. Yet, most clinical evaluations and much sleep and insomnia research rely upon self monitoring via daily sleep diaries. These are often problematic to administer and can be reactive. Therefore, we investigated comparability of two measurement modalities (self monitoring and questionnaire) in a sample of 156 community dwelling older adults, both good and poor sleepers. Results indicate significant and high correlations between corresponding scores on a retrospective sleep questionnaire and on 7 days of self monitoring on a daily sleep diary, thereby suggesting that the two measurement modalities are tapping the same domains. There were, however, significant differences between means on several variables, but there was no systematic pattern to the differences. These findings illustrate the need to tailor measurement modality—retrospective or ongoing—to the setting and the purpose of the evaluation.     

广西省中职院校护理专业师生对课程教学改革现状的评价与期望

目的调查中职卫校护理专业师生对课程教学改革现状的评价与期望,为中职护理专业课程开展基于职业能力的行动导向教学改革寻求依据。方法采用自行设计的问卷,对3所中职院校护理专业的157名教师及319名学生进行问卷调查。结果中职护理专业课程教学改革力度不够,行动导向教学实施情况不容乐观,师生对护理专业课程教学改革有明确的需求及期望。结论实施基于职业能力的行动导向教学改革,是当前中职院校护理专业课程教学改革的当务之急。     

关于在药理学课程中开展研究性学习的探讨

面对知识经济的挑战,一种新型的教学、学习模式——研究性学习逐渐兴起。本文就在药理学课程中如何开展研究性学习,以及进行研究性学习应注意的问题进行了探讨。     

实验教学改革应重视提高实验教学人员的素质

在现代医学发展的新形势下,各医学院校从改良实验室环境、实验教学内容、实验教学方法等方面不断加大实验教学改革的力度,努力提升实验教学质量,但普遍对提高实验教学人员的素质重视不够。因此着意阐述了新医学模式下实验教师应具备的素质,以期明确要求,强化实验教学队伍建设,提高实验教师素质。     

Subchondroplasty in the treatment of bone Marrow lesion in early Knee Osteoarthritis: A systematic review of clinical and radiological outcomes

BackgroundKnee osteoarthritis (KOA) is increasingly prevalent in North American society. The significant societal burden it represents makes it essential to promote and target new treatments in earlier phases of the disease. Among others, subchondroplasty is a newly documented technique using calcium phosphate injection targeting the osteochondral lesions preceding KOA, also known as Bone Marrow Lesions (BMLs). This article aimed to review the existing literature on clinical and radiological outcomes of subchondroplasty in the treatment of BMLs in KOA.MethodA systematic review was performed using PubMed, Embase, Medline and Cochrane Database of Systematic Reviews. Studies on calcium phosphate injections into BMLs for KOA and its clinical and radiological outcomes were screened and reviewed by independent evaluators.ResultsAfter screening, ten articles were included, totaling 540 patients. Follow-up ranged from 6 months to 7 years. Overall, the procedure showed significant functional and quality of life improvement, as well as pain relief, as shown by Patients-Reported Outcomes Measures (PROMs). There were very few complications reported, the most important being leakage of calcium phosphate outside the targeted site. Conversion rate to total knee arthroplasty (TKA) ranged from 14 % to 30 % at 2 years post-procedure. Long term radiological outcomes have been poorly documented.ConclusionsSubchondroplasty is a promising avenue for the treatment of KOA. However, quality evidence is still required before any real conclusions and practical management guidelines can be drawn. Prospective, randomized studies with a control group and a rigorous assessment of long-term clinical and radiological outcomes are recommended.     

出生缺陷一级预防研究进展

出生缺陷是影响人口素质和群体健康水平的公共卫生问题。实施出生缺陷的一级预防的主要措施有宣传指导,健康促进,优生咨询,风险评估,孕前优生检查,营养素补充等措施。通过一级预防措施的实施,个别出生缺陷高发形势逐步得到控制,干预工作呈现良好态势。但形势依然严峻,应抓紧预防措施的巩固提高。加强政府及部门之间的工作协调力度和多部门参与,提高技术人员的干预技术水平,统一实施筛查方法和标准,提高准确性,加强经济滞后地区的发展,落实干预措施,不断降低出生缺陷的发生率。     

CR-lipped bearing is an adequate functional solution to patients with perioperative excessive laxity in cruciate retaining total knee arthroplasty

BackgroundThe cruciate retaining lipped (CR-lipped) bearing is designed to provide more anterior-posterior (AP) stability and could be employed to resolve excessive intraoperative laxity during the cruciate retaining TKA (CR-TKA). The aim of the study was to determine whether the CR-lipped bearing in CR-TKAs with a perioperative excessive laxity allows equivalent functional results as compared to the standard CR articulation.MethodsA cohort of 111 TKAs with CR-lipped bearings was matched to a cohort of conventional CR bearings regarding age and sex. The CR-lipped bearing was used in patients with excessive knee AP laxity and the regular CR bearing was used in patients without excessive AP laxity during TKA. Various PROMs (WOMAC, KSS, SF-36) were assessed preoperatively and at 5-years postoperative in combination with revision rate and Range of Motion (ROM).ResultsPROMs did not differ significantly between both groups 5-years postoperatively. Mean ROM (flexion) 5-years postoperatively was not significantly different. The implant survivorship was 100% for both cohorts with revision for any reason as end point.ConclusionBased on these results, the CR-lipped bearing is a safe and effective solution for mild interoperatively assessed PCL laxity during CR-TKA without loss of function or decreased survivorship at 5 years. Peroperative conversion to a PS-TKA in order to obtain satisfactory functional scores might therefore not be necessary when mild PCL laxity is observed during surgery. Further research should focus on verifying this approach and longer follow-up is needed to generate data on long term survivorship.Level of evidenceLevel IV therapeutic, retrospective, cohort study.