分子遗传学课程体系的重构尝试

为了跟上分子遗传学的前沿进展和突出课程特色,我们对我校分子遗传学的课程体系进行了大幅调整,力争在囊括经典内容的同时引入新进展,在介绍基本机制的基础上拓展新应用,收到了良好的教学效果。     

中国现代人群下颌第三磨牙萌出情况的比较

目的探讨中国现代人群下颌第三磨牙(M3)的萌出特点。方法将第三磨牙分为3种类型,正常、半退化、缺失,然后比较不同时代间(新石器时代55例,青铜铁器时代191例,近代112例)各个类型出现率的差异。结果 M3正常的出现率随时代而降低,缺失的出现率随时代而升高,半退化的出现率随时代而升高。结论 M3正常的出现率随时代而降低,可能与下颌骨尺寸随时代的持续减小有关。     

现代人下颌颏形的变异及与化石人类的比较

目的分析中国现代人群颏形的表现特点及时代变异。方法将颏形分为3种类型,方形、圆形、尖形,比较不同时代间(新石器时代54例,青铜铁器时代197例,近代113例)各个类型出现率的差异。结果新石器时代颏形主要为圆形和方形,青铜铁器时代圆形颏形占绝对优势,近代主要为圆形。中国晚期智人颏形为圆形和尖形。结论颏形不同时代间有差异,颏形的变化可能与下颌骨尺寸、下颌前部形态的时代变异有关。     

PPD试验与排菌肺结核病人疗效的关系研究

目的　研究结核菌纯蛋白衍生物 (PPD)试验结果与初治排菌肺结核病人近期疗效间关系。方法　对 15 5例入院的初治排菌肺结核病人常规做PPD试验 ,专人负责皮试的注射、结果测量和记录。结果　吸收及空洞闭合速度 ,后者明显快于前者 (P <0 .0 5 )。结论　PPD皮试反应强度与初治排菌肺结核病人近期疗效之间存有肯定的正相关性     

养阴类中药成分与药理研究现状

本文综述了近年来养阴药的化学成分及药理作用,发现多糖、氨基酸、微量元素是其发挥功效的重要成分。     

Studies on memory: The cerebral spread of an engram in mice as affected by inhibitors of dopamine β-hydroxylase

Bitemporal injections of puromycin that primarily affect the hippocampal-entorhinal areas consistently cause amnesia of maze-learning in mice for 3 days after training but become consistently ineffective if given 6 or more days after training. At these later times, additional puromycin injection sites covering widespread areas of the forebrain are necessary to induce amnesia. These observations are interpreted to indicate that the locus of the engram has become more widespread within the 6-day period. Treatment with inhibitors of dopamine β-hydroxylase for 3 days following training, retarded the spread of memory from a matter of days to a period of weeks. Repeated treatment with the inhibitors restricted engram spread for about 3 months; again spread was evident about a month after the last treatment. These observations imply that the mechanisms responsible for engram spread are capable of surviving for extraordinarily long periods of time.     

百锐得治疗急性缺血性脑梗死的疗效观察

目的探讨百锐得对急性缺血性脑梗死的近期疗效。方法采用静脉点滴百锐得治疗60例急性缺血性脑梗死患者并与60例对照组比较。结果治疗组与对照组有效率相比有显著性差异(P<0.01)。结论百锐得对急性缺血性脑梗死的近期疗效肯定。     

The specialist learning disability nurse in Wales

Fisher M. International Journal of Nursing Practice 1997; 3: 188–190
The specialist learning disability nurse in Wales
This paper reflects on the development of services for people with learning disabilities within the United Kingdom and focuses on the role of the specialist nurse. The nurse's contribution to the care of this client group has been the subject of debate and controversy for a number of years. Developments within the learning disability field in Wales in particular are explored, with the All Wales Strategy for People with Learning Disabilities providing the background and context for these developments. An example of how specialist nurses from around Wales came together in order to share good and best practice is discussed. The conclusion is that the specialist learning disability nurse has a great deal to offer, but must be prepared to work together with other professionals as well as service users and their families.     

Suppression of motor conditioning by the injection of 3 M KCl in the caudate nuclei of cats

The performance of three motor conditioned responses: a pavlovian type and two instrumental responses were severely impaired in cats, after the application of 5 μl of 3 M KCl in the caudate nuclei (CN). Furthermore, during the first 2–3 min the cats kept moving from one place to the other exploring the box as if they were unable to recognize the conditioning environment and to restrain their movements. These findings are consistent with the view that the CN activity is necessary for the motor regulation which subserves learned responses, and for the analysis and/or storage mechanisms of afferent information.     

Needs and use of drug information sources in community pharmacies: a questionnaire based survey in German-speaking Switzerland

OBJECTIVES: To explore the types of drug information used by pharmacists in daily practice, their needs and wishes concerning drug information and their opinions about future changes of pharmacy practice. METHODS: Postal survey to a random sample of 223 (26% out of 859) community pharmacies from the German-speaking part of Switzerland. The 48-item questionnaires were processed automatically with the Cardiff TELEform-Software. In addition, a telephone-survey to a random sample of 20 non-responders was performed in order to test for non-response bias. RESULTS: A total of 108 pharmacists (response rate 48%) reported that the official Swiss drug reference book is still the most popular source of drug information used to solve all kinds of drug related problems. The Internet as a source of drug information is of minor importance, even though 88% of the pharmacies have Internet access. Deficits in drug information were reported for paediatrics, phytotherapy, drugs during pregnancy/lactation and for therapy guidelines. According to 35% of the pharmacists, the importance of offering drug information to customers will increase in the future. Most of the pharmacists are not afraid that Internet pharmacies would replace them. CONCLUSIONS: The results show that the majority of the community pharmacists are only partially satisfied with the sources of drug information currently available. The Internet still plays a minor role for solving drug-related problems in daily practice, even though the available infrastructure makes the community pharmacies able to use the Internet more frequently. The pharmacists need more websites tailored to their needs. The pharmacists have clear visions about possible future developments. They do, however, have to adopt quickly to the changes ahead in order to remain competitive.