全文获取类型
收费全文 | 13469篇 |
免费 | 442篇 |
国内免费 | 186篇 |
专业分类
耳鼻咽喉 | 759篇 |
儿科学 | 211篇 |
妇产科学 | 46篇 |
基础医学 | 1365篇 |
口腔科学 | 753篇 |
临床医学 | 1149篇 |
内科学 | 1197篇 |
皮肤病学 | 139篇 |
神经病学 | 1606篇 |
特种医学 | 583篇 |
外科学 | 2399篇 |
综合类 | 1421篇 |
预防医学 | 436篇 |
眼科学 | 191篇 |
药学 | 662篇 |
4篇 | |
中国医学 | 752篇 |
肿瘤学 | 424篇 |
出版年
2024年 | 41篇 |
2023年 | 303篇 |
2022年 | 369篇 |
2021年 | 433篇 |
2020年 | 398篇 |
2019年 | 387篇 |
2018年 | 402篇 |
2017年 | 327篇 |
2016年 | 348篇 |
2015年 | 347篇 |
2014年 | 832篇 |
2013年 | 856篇 |
2012年 | 732篇 |
2011年 | 860篇 |
2010年 | 667篇 |
2009年 | 642篇 |
2008年 | 624篇 |
2007年 | 662篇 |
2006年 | 551篇 |
2005年 | 482篇 |
2004年 | 464篇 |
2003年 | 408篇 |
2002年 | 293篇 |
2001年 | 326篇 |
2000年 | 252篇 |
1999年 | 214篇 |
1998年 | 176篇 |
1997年 | 192篇 |
1996年 | 148篇 |
1995年 | 131篇 |
1994年 | 125篇 |
1993年 | 88篇 |
1992年 | 107篇 |
1991年 | 71篇 |
1990年 | 86篇 |
1989年 | 63篇 |
1988年 | 61篇 |
1987年 | 75篇 |
1986年 | 70篇 |
1985年 | 61篇 |
1984年 | 64篇 |
1983年 | 22篇 |
1982年 | 41篇 |
1981年 | 38篇 |
1980年 | 36篇 |
1979年 | 30篇 |
1978年 | 23篇 |
1977年 | 29篇 |
1973年 | 31篇 |
1972年 | 26篇 |
排序方式: 共有10000条查询结果,搜索用时 156 毫秒
71.
Milton T. Edgerton Jr. M.D. Margaretha Willemina Langman ps. dra. Thomas Pruzinsky Ph.D. 《Aesthetic plastic surgery》1990,14(1):59-72
This article describes plastic surgery patients who sought symmetrical recontouring of the width of the face and skull. The basic demographic and personality characteristics of these facial width deformity (FWD) patients and the surgical procedures performed on them are discussed. Details of the surgical and psychological management of three representative cases are given. Speculative conclusions regarding the general characteristics of the FWD population are offered. Suggestions are proposed for a combined surgical-medical psychotherapeutic collaboration in managing these patients. 相似文献
72.
Summary The effectiveness of nifedipine retard as a treatment for Raynaud's phenomenon was assessed in 15 patients in a placebo controlled double blind study. An associated connective tissue disease was evident in 7 patients. Changes in finger and forearm blood flow (venous occlusion plethysmography), digital skin temperature and digital systolic pressure were measured acutely before and after a 2-week treatment period. Subjective assessment of efficacy was based on patient diary data. In addition alpha2-adrenoceptor density on platelets was measured before and after chronic nifedipine therapy in both the patient group and in an age-and-sex-matched control group. No significant haemodynamic changes were observed. Nifedipine retard significantly reduced the frequency (p<0.05) with no change in either the duration or severity of vasospastic attacks. Side effects were commono following nifedipine retard. A reduction in alpha2-adrenoceptor density on platelets was observed in patients compared to a control group (p<0.05). Alpha2-adrenoceptor density was unchanged following a 2-week treatment period with nifedipine retard. This study concludes that nifedipine retard is not effective in the treatment of Raynaud's phenomenon over a short time course. Patients with Raynaud's phenomenon have reduced alpha2-adrenoceptor densities on their platelets. 相似文献
73.
Exposure of primary cultured astrocytes for 3 days to 1 μM of either dopamine, serotonin or norepinephrine resulted in upregulation (25–34% increase in Bmax) of the peripheral-type benzodiazepine receptors (PBRs) labeled with [3H]Ro5-4864. A similar treatment with γ-aminobutyric acid [GABA] caused a 2-fold increase in the affinity (Kd) of [3H]Ro5-4864. The monoamines tested and GABA had no effect on the binding parameters of [3H]PK 11195, another selective PBR ligand. The present study indicates that Ro5-4864 binding sites are susceptible to regulation by specific neurotransmitters and provides further evidence for the distinction between Ro5-4864 and PK 11195 binding sites of the PBRs in cultured astrocytes. 相似文献
74.
丙型肝炎患者外周血单核细胞中丙型肝炎病毒复制的研究 总被引:2,自引:0,他引:2
9例临床诊断为丙型肝炎患者,研究其外周血单核细胞中HCVRNA的存在及复制。9例患者血清标本抗-HCV及HCVRNA均为阳性,采用高敏感的逆转录一套式PCR法测定其外周血单核细胞中HCV正、负链RNA,结果9例患者外周血单核细胞中7例HCV正链RNA阳性,3例HCV负链RNA阳性,证实部分丙肝患者外周血单核细胞中存在HCV的复制,表明肝细胞并非为HCV感染与复制的唯一场所。 相似文献
75.
Transient postictal hemiparesis or monoparesis is not uncommon after partial (focal) seizures. We report 2 patients who complained of severe bilateral limb weakness after generalized tonic-clonic seizures (GTCS) beginning focally. Bilateral Todd's paralysis was verified and documented in both patients. EEG and clinical evidence indicate the supplementary motor cortex as the most likely source of the seizures in both cases. 相似文献
76.
Nerve biopsy findings in Niemann-Pick type II (NPC) 总被引:1,自引:0,他引:1
A. F. Hahn J. J. Gilbert C. Kwarciak J. Gillett C. F. Bolton C. A. Rupar J. W. Callahan 《Acta neuropathologica》1994,87(2):149-154
The severe infantile form of Niemann-Pick disease type II was diagnosed in a 4-year-old girl and confirmed by demonstrating in cultured skin fibroblasts a deficiency of low-density lipoprotein-stimulated cholesterol ester synthesis of < 5% of normal. Electrodiagnostic studies revealed changes of a predominantly demyelinating motor and sensory polyneuropathy. Light microscope and ultrastructural examination of a peroneal nerve biopsy showed unique changes. Compacted myelin sheaths were disproportionately thin with marked globular irregularities in single teased nerve fibres and evidence of chronic demyelination. The majority of axons were preserved but axonal spheroids and cytoskeletal abnormalities akin to neuroaxonal dystrophy were noted. Membrane-bound multilobulated lysosomal inclusions of floccular and electron-dense material were present in Schwann cells (SC), endoneurial fibroblasts, macrophages, pericytes and endothelial cells. SC of myelinated fibres were stuffed with whorls of concentric osmiophilic membranous profiles and electron-lucent material. The findings are diagnostic and differ from those of classical Niemann-Pick disease. 相似文献
77.
本文对136例口腔颌面部损伤的伤因,颌骨骨折、牙损伤及软组织损伤等情况进行了分析。讨论了口腔颌面外伤的特点、急救处理、及骨折线上牙齿的处理等问题。强调对颌面外伤的处理必须注重整体观念。 相似文献
78.
目的了解截瘫患者医院感染的病原菌对药物敏感情况. 方法回顾分析我院自1996年9月~2003年11月,316例截瘫患者的有关临床资料. 结果 98例患者发生医院感染,医院感染率为31.01%,感染部位主要以呼吸道、皮肤软组织、手术切口、泌尿道感染为多;医院感染的病原菌主要是条件致病菌,以G-菌为主.结论医护人员必须严格无菌操作,根据细菌药敏结果合理选用抗菌药物,加强营养,提高患者机体抵抗力. 相似文献
79.
80.