温阳法治疗便秘源流述要

温阳法是中医辨证治疗便秘的重要方法之一。《黄帝内经》为温阳法治疗便秘的理论渊源;汉代《伤寒杂病论》首创温阳法治疗便秘的理法方药;隋唐时期,温阳法治疗便秘不断推陈出新;宋金元时期,多位医家对温阳法治疗便秘进行了深入的探索;而到了明清时期,温阳法治疗便秘有了较大的创新及完善。因此,追溯温阳法治疗便秘的历史源流,有助于更加了解及重视温阳法在便秘治疗中的应用。     

温经活血方外洗治疗化疗所致周围神经毒性临床研究

目的:观察温经活血方外洗防治XELOX方案引起的周围神经毒性的临床疗效。方法:将65例结直肠癌患者随机分为试验组及对照组,对照组单纯行XELOX方案化疗,试验组于化疗第1天起加用温经活血方温浴四肢,每日1次,共持续治疗2个化疗周期。比较两组患者神经毒性发生情况及其严重程度,评估患者生存质量,观察骨髓抑制的发生情况。结果:治疗第3周试验组周围神经毒性的发生率为11.8%,对照组为19.3%,两组比较,差异无统计学意义(P0.05);治疗第6周,对照组周围神经毒性发生率为23.5%,对照组为54.8%,两组比较,差异有统计学意义(P0.05);两组患者治疗后卡氏评分情况及骨髓抑制程度比较,差异无统计学意义(P0.05)。结论:温经活血方外洗可减轻XELOX方案化疗所致的周围神经毒性,临床疗效显著。     

A New Definition of an Acupuncture Meridian

This article provides a new definition of an acupuncture meridian. It suggests that a meridian consists of a distal tract of tissue that is affected by organ function. In the 1960s, Kim discovered the primo vascular system and regarded the superficial primo vessels as equating to the meridians. Instead, this article suggests that the superficial primo vessels merely underlie the meridians, in that they enable their creation, which is why some meridians are said to occur along the paths of superficial primo vessels. But the meridians themselves do not have a dedicated anatomical structure; instead they are merely tracts of tissue whose normal function is impeded when the related abdominal organ is stressed. It is hypothesized that the organ information is communicated in electrical waves that may travel through the connective tissue sheaths of the superficial primo vessels. Hence, the primo vessels serve as an inadvertent transport for this information, but the organ information is independent of the physiological purpose of the primo vascular system, as are the resultant meridians.     

Association between Pre-pregnancy Body Mass Index and Offspring Neuropsychological Development from 1 to 24 Months of Age: A Birth Cohort Study in China

Objective To explore the interactions between pre-pregnancy body mass index(BMI) and age on offspring neuropsychological development from 1 to 24 months in China.Methods In this birth cohort study, a total of 2,253 mother-child pairs were enrolled in Tianjin, China,between July 2015 and May 2018. The China Developmental Scale for Children was used to assess developmental quotient(DQ) of children aged from 1 to 24 months.Results Mixed-models analysis revealed significant age × pre-pregnancy BMI interactions for total DQ and five neurobehavioral domains(gross motor, fine motor, adaptive, language, and social; P 0.001).Age × pre-pregnancy BMI ≥ 25 kg/m~2 was associated with a negative effect on total DQ and five neurobehavioral domains, as compared to pre-pregnancy BMI 25 kg/m~2(P 0.01). Multiple comparisons showed pre-pregnancy BMI ≥ 25 kg/m~2 of mothers had a positive effect on child total DQ at the age of 1 month but a negative effect at 24 months(P 0.05).Conclusions This study supported the age × pre-pregnancy BMI interaction on offspring neuropsychological development. It also revealed a short-term positive impact of high pre-pregnancy BMI on neuropsychological development at 1 month of age, but a long-term negative effect(from 1 to24 months).     

显臣粉刺净药效学与毒理学研究

通过动物实验对显臣粉刺净进行药效学和毒理学研究。结果表明：显臣粉刺净对皮肤常见菌有明显的抑制作用,能增强免疫功能,久用无明显的毒性作用。     

白金甘胃方加减对胃食道反流病患者中医症状积分及食管下段压力变化的影响

目的:观察白金甘胃方加减对胃食道反流病患者中医症状积分及食管下段压力变化的影响。方法:选取2018年3月至2019年3月郑州市第一人民医院消化科、中医科门诊治疗的胃食道反流病患者80例,随机分为对照组和治疗组各40例,有部分病例脱落,治疗组38例和对照组33例。对照组给予泮托拉唑肠溶片、莫沙必利治疗,治疗组在对照组治疗的基础上给予白金甘胃方加减治疗。结果:两组比较,治疗组治疗后RDQ总分及各单项评分低于对照组,差异有统计学意义(P<0.05);治疗组治疗后LES静息压高于对照组,胃镜评分低于对照组,差异有统计学意义(P<0.05);两组中医证候疗效比较,对照组有效率为78.78%,治疗组有效率为86.84%,治疗组高于对照组,差异有统计学意义(P<0.05);两组胃镜下炎症疗效比较,治疗组有效率为84.21%,对照组有效率为77.42%,差异有统计学意义(P<0.05)。结论:白金甘胃方加减能改善胃食管反流病患者临床症状,改善食管下段压力。     

辽宁现代针灸名家学术特色的研究

辽宁现代针灸医家以彭静山、马瑞林以及王品山为代表。他们学术上互有交融而又独立自成体系。其学术思想具有鲜明的本土特色,内涵丰富,影响深远。本研究重点介绍了三位针灸医家的学术特色、诊疗经验和论文著述。在分析其学术思想的形成背景、诊疗特点和发展现状的基础上,探讨辽宁地区现代针灸流派的特色,在针灸流派的全面继承或创新发展方面都有重要意义。     

针灸名家指力练习的启示

针刺基本功是提高手法操作、取得临床疗效的关键环节,其主要内容就是指力。指力需要掌握恰当的方法,勤学苦练才能获得。笔者结合针灸名家贺普仁、彭静山及个人领悟,介绍指力的练习方法。     

《黄帝内经》中腧穴配伍理论及特点探析

总结归纳了《黄帝内经》中腧穴配伍的特点及规律,认为其虽然配伍腧穴数目较少,但传递了重要的配伍理念和思想,形成了腧穴配伍理论的雏形,提出了局远配穴、表里配穴等腧穴配伍基本形式,并且关注影响配伍疗效的其它因素,对后世腧穴配伍理论的发展具有重要的指导作用。     

静安口服液治疗小儿多发性抽动症的药效研究

目的：对静安口服液进行主要药效研究。方法：观察静安口服液对小鼠自发活动、协同戊巴比妥钠睡眠实验及电惊厥、注射中枢兴奋药等致小鼠惊厥模型的作用和对东莨菪碱和戊巴比妥钠所致的小鼠学习记忆障碍模型的作用以及其免疫调节作用。结果：静安口服液不同剂量组与对照组比较均具有显著镇静催眠、抗惊厥、促进学习和记忆及调节与促进免疫的作用。结论：静安口服液具有镇静催眠、抗惊厥、促进学习和记忆及调节与促进免疫的作用。