全文获取类型
收费全文 | 17095篇 |
免费 | 1006篇 |
国内免费 | 1019篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 78篇 |
妇产科学 | 39篇 |
基础医学 | 1224篇 |
口腔科学 | 318篇 |
临床医学 | 1734篇 |
内科学 | 384篇 |
皮肤病学 | 31篇 |
神经病学 | 692篇 |
特种医学 | 1052篇 |
外科学 | 6353篇 |
综合类 | 2988篇 |
现状与发展 | 1篇 |
预防医学 | 419篇 |
眼科学 | 626篇 |
药学 | 1177篇 |
15篇 | |
中国医学 | 1743篇 |
肿瘤学 | 224篇 |
出版年
2024年 | 89篇 |
2023年 | 303篇 |
2022年 | 488篇 |
2021年 | 614篇 |
2020年 | 615篇 |
2019年 | 422篇 |
2018年 | 499篇 |
2017年 | 554篇 |
2016年 | 578篇 |
2015年 | 614篇 |
2014年 | 1416篇 |
2013年 | 1233篇 |
2012年 | 1215篇 |
2011年 | 1252篇 |
2010年 | 1121篇 |
2009年 | 909篇 |
2008年 | 790篇 |
2007年 | 821篇 |
2006年 | 724篇 |
2005年 | 616篇 |
2004年 | 573篇 |
2003年 | 545篇 |
2002年 | 463篇 |
2001年 | 361篇 |
2000年 | 301篇 |
1999年 | 298篇 |
1998年 | 208篇 |
1997年 | 189篇 |
1996年 | 177篇 |
1995年 | 154篇 |
1994年 | 134篇 |
1993年 | 119篇 |
1992年 | 93篇 |
1991年 | 74篇 |
1990年 | 48篇 |
1989年 | 64篇 |
1988年 | 42篇 |
1987年 | 37篇 |
1986年 | 48篇 |
1985年 | 49篇 |
1984年 | 55篇 |
1983年 | 22篇 |
1982年 | 41篇 |
1981年 | 28篇 |
1980年 | 24篇 |
1979年 | 24篇 |
1978年 | 19篇 |
1977年 | 27篇 |
1976年 | 10篇 |
1973年 | 5篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
目的 分析、总结腰椎间盘突出症合并骨化的临床特点。方法 对近10年间手术治疗的腰椎间盘突出症合并骨化22例资料完整的病例复习、讨论、分析。结果 腰椎间盘突出症合并骨化在临床并非少见,对神经组织损伤严重,临床症状、体征有其特殊性,CT在诊断中有重要价值。结论 腰椎间盘突出症合并骨化一经诊断应尽早手术治疗。 相似文献
82.
83.
目的:探讨腰椎间盘突出症合并神经根管狭窄的临床诊断和手术治疗。方法:对1996-1999年间,因腰椎间盘突出症合并神经根管狭窄38例行手术治疗,术中均行神经根管探查并彻底松解受压神经根。结果:术后随访38例,优20例,良15例,一般2例,差1例,优良率92.11%。结论:神经根管扩大和神经根探查彻底减压是手术成功的关键。 相似文献
84.
ObjectiveT2 inversion sequence is used in routine radiology practice mainly to heighten contrast resolution within the region to be studied but no evidence exists in current literature to assess it's true efficacy for lumbar disc degeneration. The objective of this study was to analyse T2 inversion and evaluate it's efficacy in assessment of lumbar disc pathology,.Materials and methodsThis retrospective single-centre study included 50 randomly selected patients presenting with back pain and radiculopathy. T2 inversion sequence was obtained in both axial and sagittal planes in addition to routine sequences. All the Magnetic Resonance Imaging (MRI) procedures were performed on 3T. One senior Musculoskeletal (MSK) radiologist, 2 general radiologists and a spinal surgeon blinded to final results reviewed images for the various disc pathologies individually analysing conventional and T2 inversion images. Data was analysed using Fischer's test and Chi2 test with a p value of <0.05 considered as significant.ResultsFifty randomly selected patients (mean age was 47.3 years(range 35–55 years) with back pain and radicular symptoms were included. The spectrum of disc pathologies included protrusions, annular fissures, discal cysts and calcified discs. Based on the above findings, T2 inversion sequence is not proved to be an alternative imaging sequence to routine MR imaging sequences for the depiction of various disc pathologies.ConclusionT2 inversion sequence does not increase the depiction of various lumbar disc pathologies in comparison with conventional sequences when used by experienced MSK radiologists. It may highlight abnormalities better for relatively inexperienced readers such as general radiologists and spinal surgeons. 相似文献
85.
【摘要】 目的:探讨多节段前外侧入路腰椎椎间融合(oblique lumbar interbody fusion,OLIF)联合后路内固定治疗腰椎退行性侧凸伴脊柱矢状面失平衡的效果。方法:回顾性分析2017年9月~2020年4月于我院就诊并接受多节段OLIF联合后路内固定治疗的17例腰椎退行性侧凸伴脊柱矢状面失平衡患者,男3例,女14例;年龄55~81岁(67.8±6.3岁);随访时间13~39个月(25.9±7.6个月)。在术前、术后与末次随访时的全脊柱X线片测量脊柱冠状面及矢状面相关参数,包括:腰椎侧凸Cobb角、C7铅垂线-骶骨中垂线距离(C7 plumb line-center sacral vertical line,C7PL-CSVL)、胸椎后凸角(thoracic kyphosis,TK)、胸腰段后凸角(thoracolumbar kyphosis,TLK)、腰椎前凸角(lumbar lordosis,LL)、腰椎前凸分布指数(lordosis distribution index,LDI)、脊柱矢状面垂直轴(sagittal vertical axis,SVA)、脊柱骶骨角(spino-sacral angle,SSA)、躯干整体倾斜角(global tilt,GT)、GAP评分(Global Alignment and Proportion score)、骨盆入射角(pelvic incidence,PI)、骨盆倾斜角(pelvic tilt, PT)、骶骨倾斜角(sacral slope,SS)。记录术前、术后与末次随访时的Oswestry功能障碍指数(Oswestry disability index,ODI)、日本骨科协会(Japanese Orthopaedic Association,JOA)评分、腰部和下肢疼痛视觉模拟(visual analogue scale,VAS)评分。对术前、术后和末次随访时的影像学和临床指标进行统计学分析。结果:17例患者均顺利完成手术,手术时间120~480min(327.4±85.4min),出血量50~1100ml(504.7±275.1ml),融合节段3~8个(3.8±1.2个)。1例患者术后左侧大腿外侧腹股沟区感觉减退,给予营养神经药物后20d症状缓解;1例患者术中发生椎体终板骨折,调整融合器置入路径避开骨折部位,同时一期附加后路椎弓根螺钉内固定,随访未发现融合器进一步沉降。术后和末次随访时的腰椎侧凸Cobb角、C7PL-CSVL、TK、TLK、LL、LDI、GT、GAP评分、PT、SS与术前比较均有显著性差异(P<0.05),腰椎矢状面平衡相关参数均获得改善;术后与末次随访时比较均无显著性差异(P>0.05)。术后和末次随访时的ODI、JOA评分、腰部VAS和下肢VAS评分与术前比较均有显著性改善(P<0.05),末次随访时进一步改善,与术后比较差异均有显著性(P<0.05)。结论:多节段OLIF联合后路内固定术可以有效缓解腰椎退行性侧凸患者的症状,同时矫正脊柱三维畸形、重建矢状面和冠状面平衡,提高患者生活质量。 相似文献
86.
87.
目的 探讨微创经椎间孔入路腰椎椎间融合术(MIS-TLIF)中横突定位法置钉治疗腰椎退行性疾病的可行性.方法 回顾性分析2017年1月—2019年5月在新华医疗集团新华医院接受MIS-TLIF治疗的70例腰椎退行性疾病患者的临床资料,其中采用横突定位法置钉33例(观察组),采用传统人字嵴定位法置钉37例(对照组).记录并比较2组术中出血量、透视次数、置钉时间、一次置钉成功率、置钉优良率、关节突关节破坏率,在术前、术后3个月和末次随访时采用Oswestry功能障碍指数(ODI)、疼痛视觉模拟量表(VAS)评分评价患者腰椎功能及疼痛程度.结果 所有手术顺利完成,患者随访16~36(23.18±3.91)个月.观察组置钉时间、透视次数、关节突关节破坏率显著低于对照组,一次置钉成功率、置钉优良率显著高于对照组,差异均有统计学意义(P<0.05);术中出血量组间差异无统计学意义(P>0.05).2组术后3个月、末次随访时VAS评分和ODI均较术前显著改善,差异均有统计学意义(P<0.05),组间比较差异无统计学意义(P>0.05).结论 MIS-TLIF术中采用横突定位法置钉治疗腰椎退行性疾病近期疗效良好,可减少置钉时间,提高置钉成功率与准确率. 相似文献
88.
目的 分析不同年龄段非特异性腰痛患者人口学因素、临床特征及竖脊肌形态与腰椎曲度的相关性.方法 选取2016年1月—2019年12月首都医科大学附属北京安贞医院和国家电网北京电力医院收治的临床影像学资料完整的非特异性腰痛患者99例,记录患者年龄、性别、体质量指数(BMI)、腰痛持续时间、腰痛视觉模拟量表(VAS)评分.于腰椎侧位X线片测量腰椎前凸角,于腰椎横断面MRI测量L4,5节段去除脂肪信号后的双侧竖脊肌横截面积(CSA)及L4 CSA.依据患者年龄分为≥65岁组(16例)和<65岁组(83例),比较2组人口学因素、腰痛持续时间、VAS评分、竖脊肌参数和腰椎前凸角的差异,并分析腰椎前凸角与其他指标的相关性.结果 <65岁组L4,5节段竖脊肌CSA/L4 CSA高于≥65组,差异有统计学意义(P<0.05).2组性别、BMI、VAS评分、腰痛持续时间及腰椎前凸角差异无统计学意义(P>0.05).在<65岁组中,相关性检验显示性别和L4,5节段竖脊肌CSA/L4 CSA与腰椎前凸角存在相关性,多元线性回归分析显示腰椎前凸角与L4,5节段竖脊肌CSA/L4 CSA呈正线性相关.在≥65岁组中,相关性检验显示腰椎前凸角与年龄和L4,5节段竖脊肌CSA/L4 CSA存在相关性,多元线性回归分析显示年龄与腰椎前凸角呈负线性相关、与L4,5节段竖脊肌CSA/L4 CSA呈正线性相关.结论 非特异性腰痛患者性别、年龄、L4,5节段竖脊肌CSA/L4 CSA与腰椎曲度均存在相关性,<65岁的患者腰椎曲度与性别相关,≥65岁的患者腰椎曲度与年龄相关,而腰椎曲度与L4,5节段竖脊肌CSA/L4 CSA的相关性不依赖于年龄. 相似文献
89.
ObjectiveThe objective of the present study was to evaluate the safety and efficacy of percutaneous transforaminal endoscopic discectomy (PTED) and open fenestration discectomy (OFD) in the treatment of lumbar disc herniation (LDH).MethodsPatients in our hospital with LDH who received PTED (n = 71) and OFD (n = 39) from 2013 to 2014 were retrospectively studied. Patient information, including age, gender, visual analogue scale (VAS) score for low back pain and leg pain, body weight, height, Oswestry disability index (ODI), Japanese Orthopedic Association (JOA), and recurrence, was collected. The patients in the two groups were followed up for an average of 63 months after surgery.ResultsA total of 136 patients completed the operation and 110 patients were followed up completely. There was no significant difference in baseline data between the two groups (P > 0.05). The postoperative low back pain, leg pain, ODI, and JOA of the two groups were better than those preoperatively (P < 0.05). One week after surgery, the recovery of PTED patients was better than that of OFD. The ODI score of the PTED group was lower than that of the OFD group (10 [8, 12] vs 14 [11, 16]; P < 0.05), the waist VAS score of the PTED group was lower than that of the OFD group (2 [2, 3] vs 3 [2, 4]; P < 0.05), the leg VAS score of the PTED group was lower than that of the OFD group (1 [0,1] vs 1 [1, 2]; P < 0.05), while the JOA score of the PTED group was higher than that of OFD group [19(16, 20) vs 12(10, 17); P < 0.05]. There were no significant differences in ODI, JOA, waist and leg VAS scores between the two groups at 1 month after surgery and at subsequent follow‐up (P > 0.05). At the end of the follow up, 89.7% (35/39) of patients in the OFD group had excellent improvement in the JOA score, and 88.7% (63/71) of patients in the PTED group had an excellent improvement. There was no significant difference between the two (P > 0.05). There was also no significant difference in the recurrence rate between the two groups [(5/71) vs (3/39); P > 0.05]. [Correction added on 05 March 2021, after first online publication: “3/29” was amended to “3/39” in the preceding sentence.]ConclusionBoth PTED and OFD can achieve good mid‐term efficacy in the treatment of LDH but PTED has certain advantages, including the small incision, a shorter hospital stay, and quicker, earlier recovery. However, prospective randomized controlled studies with a larger sample size are needed. 相似文献
90.
Qingpeng Song Bao Hai Wenkui Zhao Xin Huang Kaixi Liu Bin Zhu Xiaoguang Liu 《Orthopaedic Surgery》2021,13(2):659
To (i) introduce the technical notes of a novel full‐endoscopic foraminotomy with a large endoscopic trephine for the treatment of severe degenerative lumbar foraminal stenosis at L5S1 level; (ii) assess the primary clinical outcomes of this technique; (iii) compare the effectiveness of this full‐endoscopic foraminotomy technique and other previous techniques for lumbar foraminal stenosis. From January 2019 to August 2019, a retrospective study of L5S1 severe degenerative lumbar foraminal stenosis was performed in our center. All patients who were diagnosed with severe foraminal stenosis at L5S1 level and failed conservative treatment for at least 6 weeks were identified. Patients with segmental instability or other coexisting contraindications were excluded. A total of 21 patients were enrolled in the study. All patients were treated by full‐endoscopic foraminotomy using large endoscopic trephine. The visual analogue scale (VAS) and Oswestry disability index (ODI) were evaluated preoperatively and at 1, 3, 6 months, and 1 year after the surgery, and the modified MacNab criteria were used to evaluate clinical outcomes at the last follow‐up. There were 10 males and 11 females with a mean age of 66.38 ± 9.51 years. Five patients had a history of lumbar surgery. The mean operative time was 63.57 ± 25.74 min. The mean follow‐up time was 13.29 ± 1.38 months. The mean postoperative hospital stay time was 1.29 ± 0.56 days. The mean preoperative VAS score significantly decreased from 7.38 ± 1.02 to 2.76 ± 1.09 (t = 19.759, P < 0.01), 2.25 ± 1.02 (t = 21.508, P < 0.01), 1.60 ± 1.05 (t = 31.812, P < 0.01), and 1.45 ± 1.10 (t = 25.156, P < 0.01) at 1 month, 3 months, 6 months, and 1 year after the operation. The mean preoperative ODI score significantly decreased from 64.66% ± 4.91% to 30.69% ± 4.59% (t = 33.724, P < 0.01), 29.44% ± 4.50% (t = 32.117, P < 0.01), 24.22% ± 4.14% (t = 33.951, P < 0.01), and 22.44% ± 4.94% (t = 30.241, P < 0.01) at 1 month, 3 months, 6 months, and 1 year after the operation. At the last follow‐up, 19 patients (90.48%) got excellent or good outcomes. One patient suffered postoperative dysesthesia, and the symptoms were controlled by conversion treatment. One patient took revision surgery due to the incomplete decompression. There were no other major complications. Percutaneous endoscopic decompression is minimally invasive spine surgery. However, the application of endoscopic decompression for L5S1 foraminal stenosis is relatively difficult due to the high iliac crest and narrow foramen. Full‐endoscopic foraminotomy with the large endoscopic trephine is an effective and safe technique for the treatment of degenerative lumbar foraminal stenosis. 相似文献