A Drosophila melanogaster hobo-white+ vector mediates low frequency gene transfer in D. virilis with full interspecific white+ complementation

Transformation of a Drosophila virilis white mutant host strain was attempted using a hobo vector containing the D. melanogaster mini-white⁺ cassette (H[w⁺, hawN]) and an unmodified or heat shock regulated hobo transposase helper. Two transformant lines were recovered with the unmodified helper (HFL1), one containing only the white⁺ marked vector, and a sibling line containing the vector as well as an HFL1 helper integration. An approximate total transformation frequency of 1% is deduced. A high frequency of wing and eye morphology mutants were also observed, suggesting that hobo may have mobilized a related element in D. virilis. The data reaffirms a relatively low transformation vector activity for the hobo transposon in D. virilis; however, nearly full interspecific expression of the white⁺ marker supports its possible function in other species as well.     

心脏病患者血清七种元素含量与血压及生化指标的关系

我们检测了心脏病患者血清微量元素Ｚｎ、Ｃｕ、Ｆｅ和常量元素Ｋ、Ｎａ、Ｃａ、Ｍｇ的含量，并与血压及生化指标作相关分析。结果发现心脏病患者Ｋ和Ｃａ／Ｍｇ显著低于对照组，而Ｎａ、Ｍｇ、Ｚｎ、Ｆｅ和Ｎａ／Ｋ、Ｚｎ／Ｃｕ则显著高于对照组。Ｋ、Ｃａ／Ｍｇ与血压呈负相关，而Ｎａ、Ｚｎ、Ｆｅ、Ｚｎ／Ｃｕ和Ｎａ／Ｋ与血压呈正相关；Ｆｅ与红细胞压积（Ｈｃｔ）呈正相关；Ｚｎ／Ｃｕ与Ｈｃｔ、甘油三酯、极低密度脂蛋白均呈正相关，而与高密度脂蛋白呈负相关。     

糖尿病性心血管病变与血清微量元素铁、铬、锰水平的相关性研究

本文研究糖尿病并发心血管病变时血清脂类、脂类过氧化产物与微量元素水平的相关性,结果发现:血清微量元素铁(Fe)与总胆固醇(T—ch)水平呈负相关,与水溶性荧光物质(WSFS)呈正相关;血清微量元素锰(Mn)与极低密度脂蛋白—胆固醇(VLDL—ch)呈负相关,与丙二醛(MDA)呈正相关;微量元素铬(Cr)与高密度脂蛋白—胆固醇(HDL—ch)呈正相关。提示:微量元素Fe、Cr、Mn为糖尿病性心血管病变的易患元素。     

家兔骨延长后血清微量元素的变化

目的 :观察骨延长术对血清微量元素的影响。方法 :采用实验家兔 6只 ,造成左胫骨中段骨延长模型 ,定期耳缘静脉采血。原子吸收分光光度仪测定血清中锌、铜、铁的含量。结果 :骨延长术后血清铜元素含量呈上升趋势 ,血清铁、锌元素含量明显下降。在延长结束后 5d时与术前比较有明显差别 (P <0 .0 5 )。结论 :骨延长术后 ,血清铁、锌元素含量呈阶段性下降 ,适时予以补充 ,有利于骨组织的修复。     

解读中医"火"概念的发生及其内涵

生产生活常识中的"火"是中医"火"概念发生的原型,经过取象比类思维,抽象出了具有气、阴阳、五行等哲学意义的"火"概念,并在此基础上构建了中医"火"的概念以及相关理论.     

碘缺乏病区碘盐防治后出生儿童头发中微量元素测定

对贵州碘缺乏病（ＩＤＤ）轻、重病区，碘盐防治后出生的轻度低智及正常智力儿童和非病区对照组儿童头发中硒（Ｓｅ）、锌（Ｚｎ）、铜（Ｃｕ）、铁（Ｆｅ）进行测定。结果显示轻病区儿童发Ｓｅ、Ｚｎ、Ｃｕ量及重病区儿童发Ｃｕ量显著低于非病区对照组。但是在轻、重病区内正常智力与轻度低智儿童头发中Ｓｅ、Ｚｎ、Ｃｕ、Ｆｅ量分别比较都没有显著差异。提示病区轻度低智儿童的发生与发中Ｓｅ、Ｚｎ、Ｃｕ、Ｆｅ的变化关系不密切。     

冠心病与血清微量元素变化的探讨

本文检测76例广州地区冠心病者血清10种微量元素(锌、锶、钼、锰、镁、铁、铜、铬、钡、硼)与健康人对照,结果显示冠心病者血清钼、镁、铜、铬、硼含量增高,其中铬、硼增高尤为显著。锌、锶、锰无显著差异。急性心肌梗塞组与其余冠心病组比较,10种微量元素血清水平均无显著性差异(P>0.05)。     

Gynandroblastoma of ovary with juvenile granulosa cell component and heterologous intestinal type glands

An ovarian gynandroblastoma in a 15-year-old girl is described. The predominant component was juvenile granulosa cell tumour. Areas of adult granulosa cell tumour and Sertoli cell elements were also present. Stromal theca and luteinised cells were identified. An additional histological finding was the presence of heterologous intestinal type glands. There was positive immunohistochemical staining of juvenile and adult granulosa cell areas with inhibin and MIC2 antibodies. Electronmicroscopy showed a close ultrastructural resemblance between tumour cells in granulosa and Sertoli cell areas, in spite of differences in architectural pattern, suggesting that both morphological components may derive from a single cell of origin. The tumour demonstrates a unique combination of elements which has not previously been described.     

冠心病中血糖与血清微量元素间的关系分析

对７５例冠心病患者依血糖水平分两组，进行１２种血清微量元素测定，旨在探讨微量元素与冠心病及糖尿病间的相互关系。结果发现锌、铬、锰、硒、钴元素高血糖组较对照组血清水平为低，呈非常显著差异（Ｐ＜０．０ｌ）；铜、镍元素增高，差异显著（Ｐ＜０．０５）；而锶、铁、砷、铅、铝元素两组间无显著差异（Ｐ＞０．１）。表明部分微量元素与冠心病及血糖间存在着密切联系。     

Correlation between renal function and pharmacokinetic parameters of inorganic fluoride following sevoflurane anesthesia

We studied the correlation between renal function and pharmacokinetic parameters of inorganic fluoride following sevoflurane anesthesia. In 30 neurosurgical patients aged 40–70 years, anesthesia was induced with midazolam and sevoflurane and maintained with sevoflurane and nitrous oxide in oxygen. Serum and urine inorganic fluoride (F⁻) levels and β₂-microglobulin (BMG), blood urea nitrogen (BUN), and serum creatinine (Cr) were measured during and after anesthesia. The decrease rate of serum F⁻ level and the area under the curve (AUC) of serum F⁻ were calculated. Correlations among sevoflurane dosage, duration of administration, peak serum F⁻ level, AUC, the decrease rate of serum F⁻ level, and the maximum values in BUN, Cr, and urine BMG during the study were investigated. Urine BMG increased significantly after surgery but returned to the preoperative level in a week. BUN, Cr, and serum BMG remained within normal ranges during the study. Sevoflurane dosage and duration of administration were significantly correlated with AUC and the maximum value of urine BMG, but not with the peak serum F⁻ level or the decrease rate of serum F⁻. AUC was significantly correlated with the maximum value of urine BMG. In sevoflurane anesthesia, sevoflurane dosage, duration of administration, and AUC affected urine BMG level, but not peak serum F⁻.