A Supervised Learning Approach for Crohn's Disease Detection Using Higher-Order Image Statistics and a Novel Shape Asymmetry Measure

Increasing incidence of Crohn’s disease (CD) in the Western world has made its accurate diagnosis an important medical challenge. The current reference standard for diagnosis, colonoscopy, is time-consuming and invasive while magnetic resonance imaging (MRI) has emerged as the preferred noninvasive procedure over colonoscopy. Current MRI approaches assess rate of contrast enhancement and bowel wall thickness, and rely on extensive manual segmentation for accurate analysis. We propose a supervised learning method for the identification and localization of regions in abdominal magnetic resonance images that have been affected by CD. Low-level features like intensity and texture are used with shape asymmetry information to distinguish between diseased and normal regions. Particular emphasis is laid on a novel entropy-based shape asymmetry method and higher-order statistics like skewness and kurtosis. Multi-scale feature extraction renders the method robust. Experiments on real patient data show that our features achieve a high level of accuracy and perform better than two competing methods.     

肌肉原发髓外浆细胞瘤的影像学表现及鉴别诊断

目的 探讨分析原发于肌肉组织的髓外浆细胞瘤的CT及MRI表现、鉴别诊断,提高对该病的认识.方法 收集经病理证实的肌肉原发髓外浆细胞瘤3例,对其影像学及鉴别诊断进行回顾性分析和总结.结果(1)发生部位:左侧竖脊肌1例,右侧闭孔内外肌1例,左股部肌肉1例;(2)肿块大小:最大径约26.4cm,最小径约4.7cm;(3)肿块...     

《中国烧伤创疡杂志》稿约

<正>《中国烧伤创疡杂志》于1989年创刊,是由卫生部主管,中国医师协会主办的国家级医学学术期刊。本刊内容新颖,结构规范,涉及面广,实用性强;普及与提高兼顾,基础与临床并重,可供从事烧伤、创伤、溃疡、整形、美容及相关学科的各级临床、教学和科研人员及医学院校学生阅读参考。本刊是双月刊,CN 11-2650/R,ISSN 1001-0726。邮发代号:82-500。     

血小板活化因子、癌胚抗原、糖类抗原724在结直肠癌中的表达及与临床病理特征的关系

目的:探讨血小板活化因子(PAF)、癌胚抗原(CEA)、糖类抗原724(CA-724)在结直肠癌(CRC)患者术前血清中的阳性表达率及与临床病理特征的关系、发病的独立危险因素。方法:选取2019年12月至2021年10月于包头医学院第一附属医院就诊的CRC患者75例为CRC组,另选取同时期在本院体检的健康志愿者75例为对照组。采用酶联免疫吸附(ELISA)法分别检测CRC患者术前及对照组的晨空腹外周静脉血PAF含量;回顾性分析上述入组患者术前血清CEA、CA-724含量,进行统计分析。结果:(1)CRC组PAF、CEA、CA-724单独检测和联合检测的阳性率分别为25.33%、42.67%、30.67%、74.67%,均高于对照组,且联合检测的阳性率均高于单独检测指标的阳性率,组间差异均具有统计学意义(P<0.05);(2)单因素方差分析结果显示,血清CEA表达水平的影响因素为患者的淋巴结转移(P<0.05);血清CA-724表达水平的影响因素为患者的年龄(P<0.05);(3)二元Logistic回归分析结果显示,PAF表达在临床病理特征之间的差异无统计学意义(P&...     

从JCEM的特色思考CJEM的发展方向

美国内分泌学会主办的《临床内分泌学与代谢杂志》是国际上特别受内分泌临床医师青睐的专业期刊,其特色是紧密结合临床实践,紧赶当代医学最先进的手段与最新发现,具有创新性、新颖性、科学性、实用性及可读性。相比之下,我们《中华内分泌代谢杂志》有许多不足之处,本文就对此差距进行剖析,并提出今后的发展方向。     

314例脑白质病变患者MRI影像学与临床特点的回顾性分析

目的研究脑白质病变的影像学改变及临床特点。方法回顾性纳入60~85岁行MRI检查示脑白质高信号改变的患者,回顾其影像学资料、临床资料,总结归纳脑白质病变的类型、严重程度,病史、认知与情绪评价结果,诊断等。结果脑白质病变类型以1型、2型为主,分别占总例数的47.45%、31.21%。病变程度均以轻度为主:脑室周围白质轻度改变占57.64%,脑深部白质轻度改变占68.79%。病史提示56.69%患高血压病,28.34%患脑卒中,29.30%患糖尿病。57.96%患者存在认知功能障碍;12.42%患者存在抑郁。66例脑梗死,42例阿尔兹海默病,88例血管性痴呆。中医诊断为"痴呆"患者以肾精亏虚(脑髓空虚)为主,占58.27%。结论脑白质病变影像学以轻中度改变为主,其发病可能与高血压、卒中、糖尿病等有关,其病变程度可能与认知功能下降有关,痴呆患者中医证型以肾精亏虚(脑髓空虚)型为主。     

护理信息学内涵分析

护理信息学是近30年来新兴的护理学专业领域,但其内涵在世界范围内仍缺乏共识。本文分析护理信息学的产生与发展、研究对象、方法 学基础、研究内容、教育模式、国内状况等问题,从护理角度探讨护理信息学的内涵,期望引起进一步的研讨．以共同推动我国护理信息学的建设和发展。     

Features and the ‘primal sketch’

This review is concerned primarily with psychophysical and physiological evidence relevant to the question of the existence of spatial features or spatial primitives in human vision. The review will be almost exclusively confined to features defined in the luminance domain. The emphasis will be on the experimental and computational methods that have been used for revealing features, rather than on a detailed comparison between different models of feature extraction. Color and texture fall largely outside the scope of the review, though the principles may be similar. Stereo matching and motion matching are also largely excluded because they are covered in other contributions to this volume, although both have addressed the question of the spatial primitives involved in matching. Similarities between different psychophysically-based model will be emphasized rather than minor differences. All the models considered in the review are based on the extraction of directional spatial derivatives of the luminance profile, typically the first and second, but in one case the third order, and all have some form of non-linearity, be it rectification or thresholding.     

临终关怀纳入社会保障制度安排的多维思考——以湖北省为例

把临终关怀事业纳入社会保障制度安排进行讨论,是基于人类生命终结的普适与不可回避性考虑,基于湖北省人口老龄化发展规模与速度所带来的赡养压力和临终老人对于社会医疗、养老保障需求的变化.加入政府的制度安排与政策导引、完善临终关怀服务体系、构建临终关怀服务供给模式和发展临终关怀专业化教育等,是发展临终关怀事业的基本策略.     

直肠印戒细胞癌和粘液腺癌临床病理分析

目的：比较研究直肠印戒细胞癌和粘液腺癌临床和病理学特点的差异。方法：回顾性地对比分折20例直肠印戒细胞癌和同期79例直肠粘液腺癌的临床和病理学特点。结果：直肠印戒细胞癌组的一年生存率65．0％，三年生存率30．0％，五年生存率5．0％。黏液腺癌组一年生存率84．8％，三年生存率58．2％，五年生存率38．0％。两在显微镜下黏液分布不同，肉眼所见大体标本相差甚远。结论：直肠印戒细胞癌较直肠粘液腺癌的诊断困难，恶性度高，预后差，临床上应对二区别对待，术中冰冻切片有助于提高病理诊断准确率，从而指导手术。