加味薏苡附子败酱散对复杂性肛瘘患者术后的疗效观察

目的:探讨加味薏苡附子败酱散联合常规换药在复杂性肛瘘术后患者中的疗效观察及对视觉模拟疼痛(VAS)评分的影响.方法:选择复杂性肛瘘患者106例作为对象,电脑抽取随机数法分为两组,各53例.两组均采用手术治疗,对照组术后常规换药干预,观察组在对照组基础上联合加味薏苡附子败酱散干预,术后14 d对患者效果进行评估,并完成6...     

Colon perforation in Ehlers-Danlos syndrome: Report of two cases and review of the literature

Two cases of spontaneous perforation of the colon in Ehlers-Danlos syndrome type IV are reported, and eight cases previously reported in the English literature are reviewed. Emergency surgery for acute free colon perforation in patients with Ehlers-Danlos syndrome should be carried out in the following standard manner: exteriorization of the perforation or resection of the involved colon with end colostomy, and either closure of the rectal stump (Hartmann procedure) or distal mucous colostomy. The reported experience although small, indicates that a high incidence of recurrent perforation can be expected if bowel continuity is reestablished. Permanent colostomy status, therefore, appears advisable, despite the young ages of most of the patients.     

Long-term exocrine function of the pancreas transplant

The long-term exocrine function of fifty-nine pancreaticoduodenal isografts was evaluated in rats for up to one year post transplantation. At one, three, six, nine, and twelve months after transplantation the grafts were cannulated and the exocrine secretion was collected. The volume, protein content, pH, amylase and trypsin concentrations, and electrolyte composition of the secretion were compared with those obtained from the host pancreas in nineteen control rats. Twenty-four hour secretion studies demonstrated normal basal function of the pancreas transplant when compared with that of the host. Pancreozymin stimulation caused an increase in volume, trypsin concentration, and amylase concentration of the graft pancreas secretion that was similar to those seen in the host. These studies indicate that there is normal exocrine secretion of pancreas transplants in the absence of rejection and that denervation of the gland has little direct effect on over-all pancreatic function.     

洁肤灵洗剂的质量控制及初步临床应用

目的:观察洁肤灵洗剂治疗妇女阴道炎的疗效.方法:437例病人被随机分成治疗组和对照组.238例为洁肤灵治疗组;199例为洁尔阴洗液对照组;两组进行用药比较.结果:治疗组总有效率为94.54%,对照组总有效率为94.47%.结论:治疗组疗效与对照组疗效无显著性差异(P＞0.05),两组疗效相当.     

以“芪英三两三”组方经验为指导治愈顽固慢性再生障碍性贫血1例

慢性再生障碍性贫血属于临床血液系统常见疾病之一，发病率呈逐年升高趋势，病程长，易反复，对患者的生活质量形成严重影响。姜苗教授认为慢性再生障碍性贫血不仅与肾虚相关，且与脾胃升降功能联系密切，强调从脾论治，抓住“虚”“瘀”“毒”3个病理因素，活用“芪英三两三”组方加减，健脾益肾，化瘀解毒。文章以完全治愈1则顽固慢性再障合并继发血小板减少病案为例，探讨姜教授治疗慢性再生障碍性贫血思路及用药方案。     

苏复宁洗液对人膀胱癌T24细胞的抑制作用研究

目的:探讨苏复宁洗液（SFN）对膀胱癌T24细胞的抑制作用。方法:采用锥虫蓝拒染法观察2 mg/ml SFN作用不同时间（20、40、60、80、100 min）对人膀胱癌T24细胞的杀伤作用;采用四甲基偶氮唑盐（MTT）法检测不同浓度（8.0、12.0、18.0、27.0、40.5 μg/ml）SFN作用48 h对T...     

Placebo controlled evaluation of Xilei San,a herbal preparation in patients with intractable ulcerative proctitis

Background and Aim: Topical mesalamine or corticosteroid has shown efficacy in patients with ulcerative proctitis, but patients often become refractory to these interventions. Xilei San is a herbal preparation with evidence of anti‐inflammatory effects. We evaluated the efficacy of topical Xilei San in ulcerative proctitis patients. Methods: In a double blind setting, 30 patients with intractable ulcerative proctitis despite ≥ 4 weeks of topical mesalamine or corticosteroid were randomly assigned to True (n = 15) and placebo (n = 15). Patients in True received suppository Xilei San (0.1 g/dose per day of Xilei San), the other 15 received placebo suppository. The initial efficacy was evaluated on day 14. Primary endpoint of the trial was avoiding relapse during 180 days, relapse meant recurrence of active disease. Riley's index was applied for endoscopic and histological evaluations, while patients' quality of life was evaluated by an inflammatory bowel disease questionnaire. Results: On day 14, the number of patients who achieved remission, clinical activity index ≤ 4 in True was significantly higher versus placebo (P < 0.04). Likewise, at day 180, an 81.8% of patients in True were without relapse versus 16.7% in placebo (P < 0.001). Further, significant endoscopic (P < 0.01), histological (P < 0.02) and inflammatory bowel disease questionnaire (P < 0.04) improvements were observed in True, but not in placebo. Conclusions: This is the first controlled investigation showing significant clinical and endoscopic efficacy for Xilei San in patients with intractable ulcerative proctitis. Topical Xilei San was well tolerated, and was without safety concerns.     

平胃散加减配针刺治疗慢性胃炎78例疗效观察

目的：观察平胃散加减配针刺治疗慢性胃炎疗效。方法：运用平胃散加减配针刺治疗慢性胃炎78例,疗程2-3周,对服药后综合疗效进行总结。结果：临床治愈65例,好转9例,无效4例,治愈率为83%,有效率为94%。结论：平胃散加减配针刺治疗慢性胃炎疗效显著。