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181.
Demographic, drug use and criminal correlates of risky drug practices were examined among 279 detained youth in NSW Juvenile Justice Centres. Binge drinking was common, with 63% reporting the consumption of at least five drinks in a row in the 2 weeks prior to incarceration. It was associated with being older, being from an English-speaking background, regular tobacco consumption and having a current drug problem. A quarter (24%) of the sample had injected an illicit drug, over one-third (37%) of whom also reported sharing needles. Injectors were more likely to be polydrug users, regular amphetamine users and have a past history of drug treatment. While 16% of the sample indicated a need for drug treatment, only 10% were currently receiving some form of treatment, most commonly counselling. Appropriate strategies are needed among this population to address gaps in treatment provision. 相似文献
182.
The relationship between route of administration and the adverse effects of amphetamine use (dependence symptoms, treatment-seeking, adverse psychological symptoms and violence) were examined among 231 Australian amphetamine users, half of whom usually injected amphetamine. Although 87% of users were recruited from non-treatment sources, a third had experienced symptoms of dependence on amphetamine, and a third had experienced an amphetamine-related health problem for which one in four had sought medical attention. There was also a high prevalence of psychological symptoms, such as depression, anxiety, paranoia, hallucinations and violence which were related to frequency of amphetamine use, and use by injection. Amphetamine users need to be better informed about the potential adverse effects of amphetamine use, and about ways in which they can reduce their risks of experiencing these harms by avoiding injecting use, and the regular use of high doses of amphetamines. 相似文献
183.
Andreas Obruca Karl Mock Wilfried Feichtinger Gerhard Lunglmayr 《Journal of assisted reproduction and genetics》1995,12(9):627-631
Purpose
Intracytoplasmic injection (ICSI) with testicular sperm was performed in 16 couples. All men had ductal obstruction and failed previous attempts of epididymal sperm microaspiration.Methods
Testis tissue was obtained by excisional biopsies and incubated in HEPES buffered EBSS medium over 24 h at 37C. Motile sperm (Grade 1 to 2) were recovered in 13 patients and fertilized a total of 62 oozytes. Four pregnancies were achieved.Results
One healthy boy and two girls (twin pregnancy) were born.Conclusions
The ongoing pregnancies revealed no fetal abnormalities on ultrasound scanning.Presented at the IXth World Congress on In Vitro Fertilization and Alternate Assisted Reproduction, April 3–7, 1995, Vienna, Austria. 相似文献
184.
185.
Vendrell JM García F Veiga A Calderón G Egozcue S Egozcue J Barri PN 《Human reproduction (Oxford, England)》1999,14(2):375-378
The incidence of meiotic abnormalities and their relationship with different spermatogenic parameters was assessed in 103 male patients with presumably idiopathic severe oligoasthenozoospermia (motile sperm concentration < or = 1.5 x 10(6)/ml). Meiosis on testicular biopsies was independently evaluated by two observers. Meiotic patterns included normal meiosis and two meiotic abnormalities, i.e. severe arrest and synaptic anomalies. A normal pattern was found in 64 (62.1%), severe arrest in 21 (20.4%) and synaptic anomalies in 18 (17.5%). The overall rate of meiotic abnormalities was 37.9%. Most (66.7%) meiotic abnormalities occurred in patients with a sperm concentration < or = 1 x 10(6)/ml. In this group, total meiotic abnormalities were found in 57.8% of the patients; of these, 26.7% had synaptic anomalies. When the sperm concentration was < or = 0.5 x 10(6)/ml, synaptic anomalies were detected in 40% of the patients. In patients with increased follicle stimulating hormone (FSH) concentrations, total meiotic abnormalities occurred in 54.8% (synaptic anomalies in 22.6%). There were statistically significant differences among the three meiotic patterns in relation to sperm concentration (P < 0.001) and serum FSH concentration (P < 0.05). In the multivariate analysis, sperm concentration < or = 1 x 10(6)/ml and/or FSH concentration > 10 IU/l were the only predictors of meiotic abnormalities. 相似文献
186.
参麦注射液对缺血大鼠心肌内钙超载的影响 总被引:14,自引:0,他引:14
目的:观察参麦注射液对大鼠缺血心肌细胞内钙超载的影响及其心肌保护作用。方法:用异丙肾上腺素制备大鼠心肌缺血模型,Fura-2 法测定大鼠红细胞胞浆游离钙浓度(EryCai);生化法测定红细胞膜钙泵(Ca-pum p)、钠泵(Na-pum p)活性,同步观察大鼠心肌组织病理变化。结果:参麦注射液治疗后EryCai较缺血组显著降低(1.68±0.10 F335/F385 vs1.56±0.15 F335/F385 P< 0.05),但仍高于对照组(1.56±0.15 F335/F385 vs1.36±0.10F335/F385 P< 0.001);钙泵(105.1±29.4 μm olPi·gHb- 1 ·2h- 1vs 126.8±30.7 μm olPi·gHb- 1 ·2h- 1 P> 0.05)及钠泵(35.1±18.2 μm olPi·gHb- 1·2h- 1 vs 43.3±10.2 μm olPi·gHb- 1·2h- 1 P> 0.05)活性较缺血组有所增高,但无统计学意义,且钙泵(126.8±30.7 μm olPi·gHb- 1 ·2h- 1 vs 168.6±39.6 μm olPi·gHb- 1 ·2h- 1 P< 0.01)及钠泵(43 相似文献
187.
目的:确定硬膜外一次性镇痛法对食管癌病人术后的镇痛效果和减少并发症的意义。方法:93 例病人随机分成实验组( T 组,51 例) 和对照组( C 组,42 例) , T 组于手术结束缝合皮肤切口时经硬膜外导管于 T6 - 7 水平注射吗啡1 mg 加1 % 普鲁卡因10 ml, C 组用阿片类药物肌肉注射镇痛。结果: T 组病人术后疼痛明显减轻,各种并发症显著下降。结论:硬膜外一次性镇痛效果确切,操作方便,副作用少,对降低术后心肺并发症很有意义,尤其对年龄大、心肺功能差的病人较适合。 相似文献
188.
生脉注射液对阿霉素致心脏损伤保护作用的实验研究 总被引:4,自引:0,他引:4
用Wister大鼠模型研究生脉注射液对阿霉素致心脏损伤的保护作用。结果:使用生脉注射液比单纯使用阿霉素,血清SOD活性升高,MDA、GOT、LDH、HBDH、LDH1/LDH2比值及心肌病理计分下降。表明;生脉注射液对阿霉素导致的心脏损伤具有保护作用,其机理与其清除氧自由基,保护SOD活性有关。 相似文献
189.
目的 :为糖尿病周围神经病变探讨有效的治疗方法。方法 :选择 65例糖尿病周围神经病变患者 ,随机分为两组 ,一组为慢心律治疗组 ,另一组为慢心律联合丹参注射液治疗组 ,以临床表现改善客观指标及运动传导速度 (MCV)、感觉传导速度 (SCV)测定做为判定标准。结果 :两组经治疗 4wk后 ,慢心律组总有效率为76 7% ,慢心律联合丹参注射液组总有效率为 94 3 %。两组肌电图显示神经传导异常率均下降 ,而以慢心律联合丹参注射液组作用较强 (P <0 0 5 )。结论 :慢心律联合丹参注射液治疗糖尿病周围神经病变更有效 相似文献
190.
薄层扫描法测定清开灵注射液中栀子甙的含量 总被引:5,自引:0,他引:5
目的:测定清开灵注射液中栀子甙的含量。方法:采用双波长薄层扫描法,测定波长为240 nm ,参比波长为310 nm ,狭缝为1-2 m m ×1-2 m m ,SX= 3 。结果:在1 ~5 μg 范围内呈良好的线性关系,平均回收率为99 .89 % 。RSD= 1-19 % (n =5) 。结论:本法简便、快速、灵敏、结果准确可靠。 相似文献