蔡光先教授运用五味异功散合过敏煎治疗小儿过敏性疾病验案举隅

蔡光先系国家级名中医,第五批全国名老中医药专家学术经验继承工作指导老师,博士研究生导师,国家有突出贡献专家,从事中医药教学、科研及临床工作40余载,擅长内科疑难杂症的诊治,临床经验丰富,学术造诣颇深,笔者有幸跟师临证学习,受益匪浅.现择其运用五味异功散合过敏煎治疗小儿过敏性疾病验案3则报道如下,以飨同道.     

脂肝康治疗非酒精性脂肪肝84例观察

目的:比较脂肝康和立普妥治疗非酒精性脂肪肝的疗效。方法:治疗组84例用脂肝康治疗,对照组84例用立普妥治疗,1个月为一疗程。共治疗1~3个疗程。结果:治疗组总有效率95.2%,对照组总有效率73.8%,两组比较有极显著性差异(P<0.01)。结论:脂肝康治疗非酒精性脂肪肝有较好疗效。     

蔡淦对东垣脾胃学说的认识

将蔡淦教授对东垣脾胃学说的认识从4个方面进行阐述,即阐阴火元气,崇《脾胃论》首方;重气机升降,治法有机揉合;论制方用药,总以胃气为本;脾胃居于中,治脾胃安五脏。     

益脑颗粒治疗缺血性脑卒中后遗症的临床研究

目的:观察补益肝肾法对于肝肾阴虚型缺血性卒中后日常生活自理能力量表(ADL)及美国国立卫生研究院脑卒中量表(NIHSS)的影响。方法:采用我院自制剂益脑颗粒,以益肝肾药物为主要组成,对缺血性卒中病人进行干预,选择肝肾阴虚型脑卒中病人166例,随机分为治疗组及对照组,对照组仅采用常规治疗,治疗组加用中药,30天为1个疗程,同时在病人入院第2天及30天后进行ADL及NIHSS评分,两组前后分别比较。结论:补益肝肾法能明显改善患者的后遗症,改善肢体功能,提高病人生活质量。     

平肝合剂对大鼠急性脑缺血模型影响的实验研究

用平肝合剂对实验性急性脑缺血模型进行脑含水量,电解质及抗氧化的研究,结果显示：平肝合剂能对抗急性脑缺血大鼠脑指数、脑含水量增加、对抗血清钙离子细胞内转移,提高脑组织超氧化物歧化酶水平,降低丙二醛水平,从而减轻脑缺血病变,保护脑组织。     

Gentiana scabra Bunge. Formula for Herpes Zoster: Biological Actions of Key Herbs and Systematic Review of Efficacy and Safety

This study reviewed the biological action of key herbs and evaluated systematically the efficacy and safety of oral Gentiana formula for herpes zoster (HZ). Experimental studies relevant to HZ were identified in PubMed. Randomized controlled trials using Gentiana formula for HZ were identified from nine English and Chinese databases. The primary outcome was evaluation of pain. Potential risk of bias was assessed. Meta‐analysis was conducted using mean difference or risk ratio with 95% confidence intervals. Key herbs Gentiana scabra Bunge, Gentiana triflora Pall, Scutellaria baicalensis Georgi, and Gardenia jasminoides Ellis have shown antiinflammatory actions through inhibition of inflammatory cytokines and pro‐inflammatory enzymes. Twenty‐six clinical studies, involving 2955 participants, were included. Modified Gentiana formula resolved pain earlier than pharmacotherapy when used alone or combined with topical Chinese herbal medicine. Incidence of postherpetic neuralgia was lower (risk ratio 0.14, 95% confidence interval 0.03 to 0.74) with modified Gentiana formula plus topical Chinese herbal medicine. Mild adverse events were reported. Antiinflammatory actions of key herbs of Gentiana formula may explain clinical benefit in hastening pain relief and decreasing postherpetic neuralgia. Few adverse events were reported. Findings were limited by study quality and diversity in intervention and comparator dosage. Copyright © 2017 John Wiley & Sons, Ltd.     

加减滋水清肝饮养发作用的实验研究

目的探讨加减滋水清肝饮的养发作用和机理。方法采用D-半乳糖皮下注射复制衰老动物模型，加减滋水清肝饮高中低剂量灌胃给药一个月。观察鼠毛的形态并比较各组间毛干和毛球直径、真皮浅层毛细血管管径、个数及新生毛囊数量、毛囊根部有丝分裂细胞数。结果高、中剂量加减滋水清肝饮能使毛干和毛球直径、皮肤毛细血管管径和数量、新生毛囊数量和毛囊根部有丝分裂细胞数明显增加（P〈0．01，P〈0．05）。结论加减滋水清肝饮养发的主要作用机制是提高毛球营养水平。     

高效液相色谱法测定护肝胶囊中五味子醇甲的含量

目的建立护肝胶囊中五味子醇甲的含量测定方法。方法比较甲醇索氏、甲醇超声、醋酸乙酯回流提取方法的提取效率,采用高效液相色谱法进行五味子醇甲的含量测定。结果高效液相色谱法测定五味子醇甲,线性为58~2320μg/ml,r=0.9999,n=6,平均加样回收率98.53%,RSD为1.39%(n=9)。结论高效液相色谱法测定五味子醇甲,方法灵敏,重现性好。     

高效液相色谱法测定肝康复口服液中芍药甙的含量

采用ＨＰＬＣ法测定肝康复口服液中芍药甙的含量,操作方便迅速,灵敏度高,重现决策     

从《扁鹊心书》浅析窦材的灸法思想

《扁鹊心书》是南宋著名医家窦材所撰.该书是窦氏数十年行医经验的总结,书中着重介绍了有关灸法的临床应用和治验,为灸法的研究发展提供了宝贵的参考材料.笔者就该书中窦材灸法学术思想的特点有：崇素灵、辨经络、治病求本、本于真元;重元阳、温脾肾、扶阳三法、灼艾第一;审虚实、取穴精、辨证证治、艾药齐施;道艾火、法阴阳、灸法养生、延年益寿.