最低装量检查法改进的探讨

目的对原有最低装量检查法进行改进,使其更具有操作性,更符合一些特殊制剂的特殊要求。方法采用比重法、容量替代法、容量加和法,分别对溃疡糊、水晶膏、氧化锌搽剂进行最低装量检查。结果原先无法进行的最低装量检查有了可行的方法。结论改进后的方法可靠、操作性强。     

双氯芬酸钠贴片治疗骨性关节炎的有效性及安全性研究

目的 研究双氯芬酸钠贴片治疗骨性关节炎的有效性及安全性。方法 采用随机、单盲、阳性药物平行对照方法，试验组给予双氯芬酸钠贴片，对照组给予双氯芬酸钠乳胶剂。记录治疗前后患者和医师对药物疗效的评价，监测不良事件的发生。结果 试验组和对照组患者对疼痛评价和总体评价的评分治疗后较治疗前下降，医师对关节压痛指数和总体评价的评分治疗后较治疗前下降，治疗后患者疼痛症状减轻。治疗过程中未见皮肤有水肿、发红、皮疹、瘙痒等及全身不适反应。血常规、肝功能、肾功能各项指标治疗前后差异无统计学意义。结论 双氯芬酸钠贴片是治疗骨性关节炎的安全有效、使用方便的外用镇痛抗炎药。     

2004年滨州市市售牙膏部分理化指标检测

[目的]了解牙膏的卫生状况,维护消费者的利益,保证消费者的身体健康。[方法]2004年5月,对滨州市销售的48种牙膏进行部分理化指标检测。[结果]48种牙膏的铅含量合格率为54.17%,砷含量全部合格;检测32种加氟牙膏,游离氟化物、可溶性氟化物和总氟化物合格率分别为28.12%、62.52%、56.25%。[结论]滨州市市售部分牙膏的铅含量超标,加氟牙膏的氟化物合格率较低。     

Gingival necrosis following the use of a paraformaldehyde-containing paste: a case report

AIM: To report on an unusual case of gingival necrosis following the use of a paraformaldehyde-containing paste in root canal treatment. SUMMARY: Paraformaldehyde preparations are toxic to hard and soft tissues. In an era of effective local anaesthesia, toxic devitalizing preparations have few applications. However, in a mobile world population, severe tissue injury may occasionally be encountered after the use of paraformaldehyde or other toxic agents in some parts of the world. Dentists should avoid such preparations and be alert of the features and management of local toxicity if they encounter it in practice. KEY LEARNING POINTS: Paraformaldehyde-containing pastes have no application in contemporary dentistry. Dentists should avoid toxic preparations for pulp devitalization. Dentists should be aware of the features and management of tissue necrosis resulting from the use of toxic dressing materials.     

Localized alveolar bone necrosis following the use of an arsenical paste: a case report

AIM: To describe some toxic effects of arsenic trioxide in the mouth, to condemn its continued use, and present a case in which a tooth was preserved despite significant bony destruction. SUMMARY: A case is presented in which severe alveolar bone necrosis resulted from leak-age of an arsenical devitalization paste into the periodontium.The tooth was root canal treated before root amputation, and restored with a cuspal coverage restoration. The tooth was observed to be symptomless and functional at the one-year follow-up. KEY LEARNING POINTS: * Arsenic and its compounds have no place in contemporary endodontics. * Dentists should protect their patients by avoiding the use of arsenic-containing materials and refusing to use products whose constituents are not known. * Localized bone necrosis may not require tooth extraction. Depending on the severity of the case, the tooth may be preserved by a combination of endodontic, periodontal,prosthodontic and maintenance therapies.     

氢氧化钙碘仿糊剂对年轻恒牙根尖诱导成形术的疗效观察

目的探讨氢氧化钙碘仿糊剂对年轻恒牙根尖诱导成形术（apexification,AP）的临床疗效。方法收集2003～2008年间在我科就诊的儿童牙外伤病例,共87颗受伤的年轻恒牙,随机分为两组,实验组45例,对照组42例,分别用氢氧化钙碘仿糊剂,氢氧化钙糊剂（calcium hydroxide paste,CH）行AP治疗。术后每3个月复诊1次,随访2年。结果实验组有效率91.12%,对照组有效率71.43%,两组间差异有统计学意义（P〈0.05）。结论氢氧化钙碘仿糊剂对年轻恒牙的根尖诱导作用较单用CH更为有效。     

谷胱甘肽在10-甲基吩噻嗪修饰碳糊电极上的电催化氧化及电分析方法

研究了谷胱甘肽(还原型, glutathione, GSH)在10-甲基吩噻嗪(10-methylphenothiazine, MPT)修饰碳糊电极(MPT/CPE)上的电催化氧化行为。GSH在裸碳糊电极(carbon paste electrode， CPE)上的直接电化学氧化过程十分迟缓， 但在MPT/CPE上于0.702 V处出现一个不可逆氧化峰， 氧化电流大幅度增大。计时电流(chronoamperometry， CA)实验测得该电催化氧化反应速率常数k为(5.44±0.03)×10² (mol·L^-1)^-1·s^-1。用线性扫描伏安法(linear sweep voltammetry, LSV)测得催化氧化峰电流与GSH在5.0×10^-6～2.0×10^-3 mol·L^-1呈良好的线性关系， 线性回归方程I_pa=3.536c+2.117， r=0.999 0， 检测限为1.0×10^-6 mol·L^-1。同时用本方法对含GSH的市售药品进行了含量测定， 结果可靠。     

改良Cavital糊剂充填根管的研究

作者用改良 Cavital 糊剂对90例慢性牙髓炎、根周炎根充,并以常规根充作对照,经过6年的追踪观察。结果表明:两组的症状均消失。X 线片显示:绝大部分的根尖病变消失或明显缩小。两种根充的临床疗效无显著性差异(P>0.05)。对照组标本的光镜和扫描电镜观察均未见组织学的修复;而实验组则显示修复性牙本质和牙骨质形成,使根端孔闭锁,达到生物学性封闭的最理想的效果。作者认为:改良 Cavital 糊剂是一种理想的根充材料,值得推广。     

聚氯乙烯增塑糊流变行为研究——Ⅲ、稀释剂和分散剂的影响

以石油溶剂为稀释剂,4-甲基-2-戊酮(Ⅰ)和2-乙氧基乙醇(Ⅱ)为分散剂,研究了不同PVC树脂增塑糊的粘度特征。结果表明,由于PVC是极性聚合物,分散剂的分散效果主要决定于它的极性,Ⅰ的分散效果优于Ⅱ。若PVC含有聚氧乙烯基型表面活性剂,其糊用PVC树脂颗粒能较好地分散。     

胎膜治疗Ⅲ期压疮的效果观察

目的探讨胎膜治疗Ⅲ期压疮的效果。方法76例97处Ⅲ期压疮随机分为3组,A组(32处)给予胎膜治疗,B组(32处)给予鸡蛋膜治疗,C组(33处)给予润湿烧伤膏治疗;观察各组经2个疗程处理后的抗菌消炎、去腐、生肌、总疗效(治愈)情况。结果3组Ⅲ期压疮经2个疗程治疗后消炎、去腐、生肌、总疗效(治愈)治疗效果比较,A组明显好于B组和C组,有显著性差异(P<0.05)。结论胎膜治疗Ⅲ期压疮的疗效显著,是治疗Ⅲ期压疮的好方法。