青鹏膏剂治疗膝骨性关节炎疗效观察

目的:观察青鹏膏剂对膝骨性关节炎治疗的有效性及安全性。方法:膝骨关节炎患者80例,随机分为试验和对照两组,各40例。试验组为青鹏膏剂,对照组选用双氯芬酸二乙胺乳剂,两药均每日2次局部外用,涂布于患侧膝关节,疗程4w,评估治疗前后膝骨性关节炎的临床总积分和有效率,并纪录不良反应。结果:治疗4w后,试验组和对照组的临床总积分与治疗前相比,分别下降至(9.22±7.58)和(11.25±7.22),总有效率分别为92.5%、87.5%,但两组比较差异无统计学意义。均无明显不良反应。结论:青鹏膏剂治疗膝骨关节炎的近期疗效肯定,安全性好。     

超微肿痛贴配合牵引治疗腰椎间盘突出症患者疗效及对血清TNF-α的影响

目的:观察超微肿痛贴配合牵引治疗腰椎间盘突出症的疗效并对血清TNF-α的影响。方法:选取符合标准的腰椎间盘突出症患者60例,完全随机分法分为对照组及观察组,每组各30例。对照组行腰椎牵引治疗,观察组行超微肿痛贴外敷配合腰椎牵引法治疗。10d为一疗程,共治疗1疗程。比较2组临床疗效、日本骨科协会腰痛功能评价表评分(JOA)视觉模拟评分(VAS)及血清肿瘤坏死因子-α(TNF-α)水平。结果:治疗前2组患者JOA评分、VAS评分及TNF-α水平均无明显差异(P>0.05),治疗后观察组JOA评分均比对照组高,VAS评分及血清TNF-α比对照组低,差别均具有统计学意意义(P<0.05)。结论:采取超微肿痛贴外敷并配合牵引的治疗方法可明显改善临床症状,也明显降低了血清中TNF-α的含量,其效果优于单纯腰椎牵引治疗。     

The effects of Ledermix paste on discolouration of immature teeth

AIM: The aims of this study were to: (i) investigate the effects of Ledermix paste as an intracanal medicament on discolouration of immature teeth, (ii) examine whether the discolouring effects were related to the method of application, (iii) examine the effects of sunlight upon discolouration of immature teeth and (iv) compare the degree of discolouration between mature and immature teeth. METHODOLOGY: The root canals of 45 immature extracted human teeth were prepared and filled with either Ledermix paste, calcium hydroxide [Ca(OH)2], or saline. In group 1, Ledermix paste was only placed apical to the cemento-enamel junction (CEJ) whilst in groups 2 and 3, the paste filled the entire pulp chamber and the root canals. In group 4, Ca(OH)2 paste and in group 5, saline (control) were allowed to fill the pulp chamber and the root canals. Group 3 teeth were kept in the dark and the other groups were exposed to daylight for 12 weeks. RESULTS: After 12 weeks, sunlight exposure had caused dark grey-brown staining in the Ledermix groups but this did not occur when the teeth were kept in the dark. More severe staining was noted when Ledermix paste filled the pulp chamber than when the paste was restricted to below the CEJ and when teeth were exposed to sunlight. When compared to the results of a similar study using mature teeth, the results were similar but the immature teeth were more severely stained than the mature teeth. The Ca(OH)2 paste caused an increase in lightness and yellowness in immature teeth. CONCLUSION: It was concluded that Ledermix paste may cause discolouration of immature teeth. Such effects can be minimized if placement of the paste is restricted to below the gingival margin. Clinicians should ensure that Ledermix paste is not left on the walls of access cavities, especially in immature teeth.     

双歧杆菌的完整肽聚糖对实验性大肠癌的抑制作用及诱导其凋亡

目的　探讨分叉双歧杆菌的完整肽聚糖在体内对大肠癌的抑制作用及其抑瘤机制。方法　以大肠癌裸鼠移植瘤为动物模型,观察移植瘤的生长速度,同时利用透射电镜、原位末端标记技术及免疫组化技术原位观察了大肠癌裸鼠移植瘤的超微结构、凋亡细胞密度以及Ｂｃｌ２ 、Ｂａｘ 蛋白表达率及其阳性细胞密度。结果　完整肽聚糖注射组大肠癌移植瘤的生长速度显著慢于对照组,完整肽聚糖的抑瘤率达５１ ．４１ ％ ;此外完整肽聚糖注射组移植瘤组织中可见多量的处于凋亡不同时期的瘤细胞,其凋亡细胞密度、Ｂａｘ 蛋白表达率以及阳性细胞密度均显著高于肿瘤对照组（ Ｐ＜０ ．０１）,而Ｂｃｌ２ 蛋白的表达情况则相反。结论　分叉双歧杆菌的完整肽聚糖在体内能显著抑制大肠癌的生长,并能诱导它的凋亡     

Compaction of Cohesive Granular Material: Application to Carbon Paste

Carbon-like materials such as the anode and the ramming paste play a crucial role in the efficiency of the Hall–Héroult process. The mechanical behavior of these materials during forming processes is complex and still ill-understood. This work aimed to investigate experimentally the mechanical behavior of a carbon paste used in the aluminum industry under different loading conditions. For this purpose, experiments consisting of (1) relaxation tests at different compaction levels, (2) quasi-static cyclic tests at several amplitudes, (3) monotonic compaction tests at varied strain rates, and (4) vibrocompaction tests at different frequencies were carried out. The obtained results highlight some fundamental aspects of the carbon paste behavior such as the strain rate’s effect on the paste compressibility, the hardening-softening behavior under cyclic loadings, the effect of cycling amplitude on the stress state and the paste densification, and the frequency effect on the vibrocompaction process. These results pave the way for the development of reliable rheological models for the modeling and the numerical simulation of carbon pastes forming processes.     

根管消毒药物缓解乳磨牙根尖周炎临床症状的疗效分析

目的：对比四种临床常用的根管消毒药物缓解乳磨牙根尖周炎临床症状的效果。方法 选择根尖周炎乳磨牙160颗,随机分为四组,每组40颗,根管预备超声荡洗后,A组封入抗生素糊剂,B组封入Vitapex糊剂,C组封入氢氧化钙糊剂,D组封入樟脑酚棉球,10 d后复诊,对四种根管消毒药物缓解乳牙根尖周炎临床症状的效果进行评价。结果 在10d后脓肿消除方面抗生素糊剂组效果优于其他三组（P=0.005）,Vitapex组与氢氧化钙组效果,均优于樟脑酚组（P＜0.05）。术后24h内疼痛的发生率抗生素糊剂组术后24 h内疼痛发生率低于Vitapex组（P=0.014）和氢氧化钙组（P=0.045）。10 d后疼痛的比例各组之间无统计学差异。结论 抗生素糊剂能够有效缓解乳牙根尖周炎的临床症状。     

Hydration Properties of Cement with Liquefied Red Mud Neutralized by Nitric Acid

An increasing amount of red mud (RM) is being generated globally due to the growth in aluminum production. To avoid RM pollution, low-cost methods for effectively recycling RM are being investigated. We propose a method for recycling RM as a construction material. Liquefied RM (LRM) was neutralized by nitric acid and added to cement paste, and the hydration heat, compressive strength, and hydration products were investigated. The cement paste with neutralized LRM had a higher compressive strength than that of plain cement paste and cement paste with LRM without neutralization at 1 day of aging; this indicates that nitric acid neutralization increases the early-age strength. Furthermore, the cement paste with 10% neutralized LRM showed 28 days-compressive strength and hydration heating curves similar to the plain mixture, indicating the positive impact of LRM neutralization on the strength. It was noted that a greater quantity of portlandite was produced earlier in cement paste with neutralized LRM than in that without. Therefore, the proposed method of using RM as a concrete additive has the potential to reduce the cost and environmental impact of both construction materials and RM waste management.     

Low Recombination Firing-Through Al Paste for N-Type Solar Cell with Boron Emitter

A kind of low recombination firing-through screen-printing aluminum (Al) paste is proposed in this work to be used for a boron-diffused N-type solar cell front side metallization. A front side fire-through contact (FTC) approach has been carried out for the formation of local contacts for a front surface passivated solar cell. With a low contact resistivity (ρ_c) of 1.0 mΩ·cm², good ohmic contact between the boron-doped front surface of the silicon sample and the Al paste was realized. To obtain a good energy conversion efficiency, a balance can be achieved between the open circuit voltage (V_oc) and contact resistivity (ρ_c) of the cell by combining suitable Al powders and appropriate additives. The detailed micro-contact difference in Si/metallization between the firing-through Al paste and silver-aluminum (Ag-Al) paste was analyzed. The dark saturation current density beneath the metal contact (J_{0, metal}) of the Si/metallization region using our firing-through Al paste was discussed, which was proven to be 61% lower than using Ag-Al paste. The pseudo energy conversion efficiency of the cell using Al paste measured by Suns-V_OC was also higher than using Ag-Al paste. The role of Al paste in low surface metal recombination is discussed. The utilization of this new kind of Al paste was much cheaper and more convenient, compared to the traditional process using Ag or Ag-Al paste.     

皮敏消胶囊联合松馏油糊剂治疗阴囊激素依赖性皮炎疗效观察

目的观察皮敏消胶囊联合松馏油糊剂治疗阴囊激素依赖性皮炎的安全性及疗效。方法 66例患者随机分为两组。系统用药:治疗组口服皮敏消胶囊4粒,3次/d,对照组口服赛庚啶片4mg,1次/晚。局部治疗:治疗组给予松馏油糊剂封包治疗,1次/24h。对照组给予氟芬那酸丁酯软膏外用,2次/d。两组病例均治疗观察4周评定疗效,同时对痊愈病例停止用药,随访1个月观察远期疗效。结果治疗组完成32例,痊愈显效率84.38%;对照组完成29例,痊愈显效率58.62%。χ2=5.02,P<0.05。治疗组近、远期疗效和安全性均优于对照组。结论皮敏消胶囊联合松馏油糊剂治疗阴囊激素依赖性皮炎安全可靠,疗效较好,有临床使用价值。     

糊状饮食对中度吞咽障碍老年患者营养状态及吞咽功能的影响

目的探讨糊状经口饮食对中度吞咽障碍老年患者营养状况及吞咽功能的影响。方法成立多学科团队小组,对老年吞咽障碍患者进行吞咽功能评估及安全进食宣教和训练,将符合入选标准的长期住院老年中度吞咽障碍患者,根据自愿原则和配对原则,分为观察组和对照组各20例,对照组根据吞咽状况,兼顾患者的口味、意愿,进食半固体软食、浓流质、部分糊状饮食等;观察组将所有食物和液体,按专业的方法制成全糊状饮食,两组患者均自行经口进食或喂食。观察比较干预前后两组患者进食情况、营养状况和吞咽障碍程度。结果干预90 d后,观察组营养素摄入量、营养生化指标均高于对照组(P0.05);才滕氏吞咽障碍程度评估,观察组级数有1例上升,无下降;对照组有5例下降,差异有统计学意义(P0.05)。结论糊状饮食能改善老年中度吞咽障碍患者的营养状况,延缓吞咽障碍的进展,是便于推广的方法。