Normal morphology of sacroiliac joints in children: magnetic resonance studies related to age and sex

Objective. To determine in a prospective study the normal MRI morphology of the sacroiliac joints (SIJs) in relation to age and sex during adolescence. Design and patients. A total of 98 children (63 boys, mean age 12.7±2.8 years; 35 girls, mean age 13.7±2.3 years), ranging in age from 8 to 17 years, with juvenile chronic arthritis (JCA) but without signs of sacroiliitis fulfilled the study prerequisites (no back pain and no pathologic changes of the SIJs on physical examination before MRI in a 1.5-year follow-up). An additional eight HLA-B27-negative boys and eight HLA-B27-negative girls without arthritis served as controls. The MRI protocol comprised a T1-weighted SE sequence, an opposed-phase T2*-weighted GE sequence, and a dynamic contrast-enhanced study in single-section technique. Results. Noncontrast MRI permitted differentiation of “open” from ossified segmental and lateral apophyses of the sacral wings, with a significant difference in age (P <0.05) between children with open and ossified apophyses. Ossification of the apophyses of the sacral wings was seen significantly earlier (P <0.05) in girls than in boys. Girls also had a significantly higher incidence of transitional lumbosacral vertebrae, pelvic asymmetries, and accessory joints. In the contrast-enhanced opposed-phase MRI study, normal cartilage of the SIJs showed no contrast enhancement whereas the joint capsule showed a moderate enhancement. Conclusion. There are significant age- and sex-related differences in the normal MRI morphology of juvenile SIJs. Our findings might serve as a standard of comparison for the evaluation of pathologic changes – in particular for the early identification of juvenile sacroiliitis.     

青海地区1204例口腔颌面部肿瘤,囊肿,瘤样病变分析

本文对青海地区1204例口腔颌面部肿瘤、囊肿、瘤样病变的病变部位、性质、年龄及性别进行分析。结果为良性肿瘤634例（52．66％），以血管瘤和涎腺混合瘤最多见。恶性肿瘤232例（1．27％），以鳞状细胞癌居第一位，平均患病年龄48岁，随年龄增长，逐年递增。囊肿306例（25．41％），多发生在去下腺。瘤样病变32例（2．66％），多为牙龈瘤。本组良性肿瘤女性高于男性，血管瘤居第一位。良恶性肿瘤之比为2．73∶1，与国内有关报道略有不同。     

Free vascularized jejunum interposition for pharyngoesophageal reconstruction after total laryngopharyngectomy

The records of 28 patients who underwent free jejunal graft reconstruction after resection for cancer involving the pharynx were analysed. Seven patients had a T₃ carcinoma, 15 patients T₄ and six patients recurrence after laryngectomy. Ten patients had received radiotherapy in the past. Post-operatively, 15 patients (54%) had complications and two patients (7%) died. No significant difference was observed in the complication rate between the group that received radiotherapy in the past and those who did not. Nineteen patients received post-operative radiotherapy. Nine patients had no radiotherapy on the basis of complete resection or because of serious complications. For the whole group the 2-year recurrence free period and survival were 42% and 51% respectively. The postoperative radiotherapy group had a significantly better survival (73%) and recurrence free period (63%) than the group without post-operative radiotherapy (0%). Thus, post-operative radiotherapy seems indicated irrespective of resection margins.     

Ethical Issues in Psychotherapy

Abstract: The goal of psychotherapy is not only the dissolution of the symptoms, but also to attempt to bring about an improvement in adaptability and deepening the achievement of self-understanding. The nature of psychotherapy is based on the relationship between the therapist and patient. Such a goal and nature mean that some kinds of psychotherapy are beyond the medical model. In this paper ethical issues in psychotherapy are discussed as follows. 1) some complicated matters in informed-consent, 2) the hit or miss techniques of the poorly trained therapist, 3) the protection of privacy, 4) the sexual misconduct of therapists with patients, 5) special consideration for child-adolescent patients.     

人血浆前白蛋白的分离和纯化

建立一种新的分离纯化人血浆前白蛋白（ＰＡ）的方法。由酚试剂沉淀后的血浆，通过离子交换树脂分离所得ＰＡ，用高效液相色谱仪（ＨＰＬＣ）进行纯化，经ＳＤＳ－聚丙烯酰胺凝胶电泳测定，其分子量在５５０００左右，纯度达到电泳纯和免疫纯。此法步骤简单，用血量少，适用于实验室常规操作和临床人体研究。     

Nitric oxide in paraventricular nuclei of rat hypothalamus under extreme conditions

The activity of nitroxide synthetase (NOS) was studied histochemically and levels of oxytocin and vasopressin immunocytochemically in rat hypothalamus paraventricular nuclei in on-earth experiments simulating space flight conditions with landing. Colonization of oxytocin and NOS was found in large-cell neurons of paraventricular nuclei. After 15 days under conditions of simulated microgravitation followed by 1-day double gravitation and a short-term (1 day) macrogravitation, activities of NOS and content of neuropeptides increased in large-cell neurons of paraventricular nuclei of experimental animals. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 3, pp. 282–284, March, 1998     

Insults to the body civil: Mistreatment of elderly in two Plains Indian tribes

The mistreatment of elderly is subject to various social constructions. On two geographically distinct Plains Indian Reservations which we call Lone Mountain and Abundant Lands, the abuse or neglect of elderly is construed as a health problem which is a dysfunction of the community as a whole. Both physical abuse and neglect are more common on the Lone Mountain Reservation, occurring in association with other indicators of community disorganization such as unemployment and substance abuse. On the Abundant Lands Reservation physical abuse was categorically denied and what neglect existed appeared to be a function of role strain, geographic dispersal, climate and terrain. We attribute differences in the prevalence of mistreatment of elders to variations in economic opportunities for younger residents. Examining the historical and present contexts of intergenerational relationships on the reservations, we discuss the implications of this study for social exchange theory and policy applications.This research was supported by the Gerontological Society of America AppliedThis research was supported by the Gerontological Society of America AppliedThis research was supported by the Gerontological Society of America AppliedThis research was supported by the Gerontological Society of America AppliedThis research was supported by the Gerontological Society of America AppliedThis research was supported by the Gerontological Society of America Applied     

ART技术封闭恒牙的3年临床效果观察

目的 :评价非创伤性充填 (ART)技术对恒牙窝沟封闭后 ,封闭剂保留及新生龋病发生情况。方法 :1996年在四川省德阳市 4所中学选取 12～ 13岁儿童 14 0名作 191个ART封闭。采用WHO的ART标准器械 ,德国ESPE公司生产的高强度玻璃离子材料 ,对选择的牙面窝沟进行封闭 ;操作者为经中等口腔专业训练的医生。试验 3年后对ART封闭及牙龋病情况进行评价。结果 :封闭后 1、2、3年的封闭成功率分别为 89.6% ,78.8% ,71.9%。试验后 1年没有新生龋齿的发生 ,试验后 2、3年 ,龋患率较低 ,分别为 1.6% ,2 .8%。结论 :ART封闭试验 3年的保存率较高 ,新生龋发生率低 ;作为恒牙龋病防治的措施是适合和可接受的 ;是一种适合于在学校、社区开展的有效、实用的龋病预防方法。     

引导科技干部保持医院发展转型期间和谐心态的着力点

当前部队医院正处于发展转型期，如何引导科技干部适应转型发展新形势，经受住各种考验，始终保持理性平和、协调平衡、积极向上的心理状态，是一个不容忽视的现实问题，也是事关医院内部和谐和医院建设发展又好又快的大事，更是我们思想政治工作者必须着力认真研究、加以解决的重要课题。