鲜地黄中梓醇提取工艺

对鲜地黄中梓醇的提取方法进行优选 ,采用正交设计法 ,确定了最佳提取工艺 ,即 3倍量甲醇 ,加热回流提取2次。     

蒙药三子胶囊剂成型工艺研究

目的研究蒙药三子胶囊剂的成型工艺及质量控制标准。方法通过测定内容物的休止角、堆密度、吸湿率等确定最佳成型工艺;采用高效液相色谱法(HPLC)测定三子胶囊剂中有效成分栀子苷含量。结果三子胶囊内容物含药材细粉30%时,25℃吸湿率为5.46%,临界相对湿度(CRH)为75%;胶囊中栀子苷含量控制约为12.61~15.30 mg/粒。结论以此工艺制备三子胶囊质量符合相关要求。     

Quality of performance of everyday activities in children with spina bifida: a population-based study

Aim:  The aim of this study was to evaluate the quality of the performance of everyday activities in children with spina bifida.
Methods:  Fifty children with spina bifida (of 65 children in a geographic cohort), aged 6 to14 years, were evaluated with Assessment of Motor and Process Skills.
Results:  Compared with age-normative values, 60% of the children with spina bifida were found to have motor ability measures below 2 SD and 48% process ability measures below 2 SD. Most of the children with spina bifida had difficulties performing well-known everyday activities in an effortless, efficient and independent way, relating to both motor and process skills. The motor skills hardest to accomplish involved motor planning and the process skills hardest to accomplish were adaptation of performance and initiations of new steps, thus actually getting the task done.
Conclusion:  To reach autonomy in life, children with spina bifida may need particular guidance to learn not only how to do things but also how to get things done.     

Radiologist Use of and Perceived Need for Patient Data Access

Given the increasing volume of radiological exams, the decreasing frequency of direct communication with the referring provider, and the distribution of patient data over many clinical systems, radiologists often do not have adequate clinical information at the time of interpretation. We have performed a survey of radiologists to determine the need and actual utilization of patient data at the time of image interpretation. Our findings demonstrate that most radiologists want more clinical information when interpreting images and that this information would impact their report, but they are discouraged by the time it takes to access this information. In addition, current mechanisms for monitoring necessary patient follow-up are inadequate.     

需要层次理论在提高护士工作满意度中的应用及效果评价

目的提高护士工作满意度。方法以马斯洛的需要层次理论作为理论依托，对33例临床护理人员采取相应的干预措施并对干预前后护士工作满意度进行调查分析。结果实施干预后，护士在排班，被认可和表扬，工作与家庭间平衡，对工作的支配及参与决策的机会，专业发展与个人发展机会五个方面满意度明显提高。结论针对性的干预措施对提升护士的工作满意度有积极作用。     

浅谈医疗仪器设备的技术验收

仪器设备的验收是保证医院医疗仪器设备质量的第一步。验收的程序是否有序、完整关系着验收结果是否合格。只有加强医疗设备验收的管理工作,才能促进医院医疗仪器设备的管理工作,维护医院的经济效益。     

Design and In-line Raman Spectroscopic Monitoring of a Protein Batch Crystallization Process

Raman spectroscopy was used to design and monitor a lysozyme protein batch crystallization process in a lab scale study to facilitate the design of a pharmaceutical protein manufacturing process. A D-optimal design that consisted of 18 experiments was performed to elucidate the effect of temperature, concentration of the precipitating agent, time of crystallization, and possible interactions between these three factors on the Raman scattering changes. A polynomial mathematical model was calculated relating the scattering of the lysozyme solutions measured at individual Raman shifts to the significant factors obtained in the previous crystallization experiment. The 2,940-cm⁻¹ band provided the highest correlation values indicative of small prediction errors and good predictive ability for the crystallization model. Raman scattering signals obtained during the experiments were used as input to obtain a response surface for the factors studied and elucidate the relationship between the crystallization process conditions and the crystals obtained. The main factors affecting the crystallization process were the sodium chloride concentration and temperature.     

医疗器械灭菌包装设计的几个基本要求

医疗器械灭菌包装（MDSP）的基本原理及在实践中的实现。     

试论医院流程化管理形成的基础——过程方法

一些医院采用了流程化方式进行医院管理活动，由于普遍存在着对流程机制、实质内涵以及流程管理认识和操作能力上的不足，因此收到的效果不大。医院流程化管理的基础应是对过程进行的科学规范化的管理，应采用先进的“过程方法”理论和手段对现有的医院流程内容进行完善和改进，切实提高组织流程化管理水平。     

农村城市化进程中乡村医师的管理和发展

上海市宝山区在农村城市化进程中以乡村医师管理和发展的实践研究，分析了乡村医师的现状与问题，提出了农村城市化进程中乡村医师管理与发展的若干对策。