老年痴呆与糖尿病

据西班牙《国家报》报道，老年痴呆症(阿尔茨海默氏症)和糖尿病是困扰发达国家的两大流行病，而最近的一项研究发现，这两种病之间还存在着某种联系。研究得出：之间的三方面关系：首先，胰岛素不仅生成于胰腺，同样也生成于大脑中；其次，在老年痴呆症病人的体内，脑胰岛素的含量有所降低；最后，老年痴呆症患的脑受体数量减少，而后的正常工作需要有胰岛素的支持。证明大脑胰岛素的变化同老年痴呆     

国内外脑保健产品研究开发现状与前景分析

大脑是人体神经中枢所在，无容置疑大脑作为人体器官，它与其它器官一样也会逐渐衰老。一旦发生脑衰无疑会严重影响人们的生活质量。随着世界各国老龄化程度的加剧，阿尔茨海默氏症（老年痴呆症）发病率正在快速上升。WHO预测全球目前至少有上千万老年人患有阿尔茨海默氏症。目前医学界尚无一种可有效治愈老年痴呆症的手段。     

中年独居易患早老性痴呆症

美国健康新闻网日前报道,如果人在中年时就单独居住,会增加其到老年时患阿尔茨海默氏症（即早老性痴呆症）的风险。     

新型激素治疗阿尔茨海默氏症及中风

美国圣路易斯大学研究人员研究出一种新疗法可潜入大脑治疗阿尔茨海默氏症和中风。医学博士William A．Banks（美国圣路易斯大学老年医学和药理生理学教授）说：“我们发现了一个独特的途径使药物进入大脑,试图打破阻止药物进入大脑的屏障。”     

Volumetric magnetic resonance imaging classification for Alzheimer’s disease based on kernel density estimation of local features

Background The classification of Alzheimer's disease (AD) from magnetic resonance imaging (MRI) has been challenged by lack of effective and reliable biomarkers due to inter-subject variability.This ar...     

Hydrogen sulfide and nervous system regulation

Objective  This review discusses the current status and progress in studies on the roles of hydrogen sulfide (H₂S) in regulation of neurotoxicity, neuroprotection, and neuromodulator, as well as its therapeutic potential for neurodegenerative disorders.

Data sources  The data used in this review were mainly from Medline and PubMed published in English from 2001 to August 2011. The search terms were “hydrogen sulfide”, “neuron”, and “neurodegenerative disorders”.

Study selection  Articles regarding the regulation of neuronal function, the protection against neuronal damage and neurological diseases, and their possible cellular and molecular mechanisms associated with H₂S were selected.

Results  The inhibited generation of endogenous H₂S is implicated in 1-methy-4-phenylpyridinium ion, 6-OHDA, and homocysteine-triggered neurotoxicity. H₂S elicits neuroprotection in Alzheimer’s disease and Parkinson’s disease models as well as protecting neurons against oxidative stress, ischemia, and hypoxia-induced neuronal death. H₂S offers anti-oxidant, anti-inflammatory and anti-apoptotic effects, as well as activates ATP-sensitive potassium channels and cystic fibrosis transmembrane conductance regulator Cl^- channels. H₂S regulates the long-term potentiation (LTP) and GABA_B receptors in the hippocampus, as well as intracellular calcium and pH homeostasis in neurons and glia cells.

Conclusions  These articles suggest that endogenous H₂S may regulate the toxicity of neurotoxin. H₂S not only acts as a neuroprotectant but also serves as a novel neuromodulator.

     

患早老性痴呆症的老人不易得癌症

<正>美国一项最新研究成果发现,老年人如果患上阿尔茨海默氏症(即早老性痴呆症),就不易再得癌症;相反,癌症患者也不易得阿尔茨海默氏症。美国华盛顿大学医学院研究人员选择了3020名65岁以上     

茶中有益健康的成分有哪些

<正>往往人们知道饮茶有很多好处,但却说不出个所以然。其实,无论新茶还是陈茶,对健康有益的成分主要有以下几类:茶多酚是茶叶中含量最多的可溶性成分,是茶叶中最重要的生理活性物质,它具有非常强的抗氧化活性,因此,茶叶对多种人体常见病具有预防和治疗效