识别生活中“加料食品”

蘑菇：雪白透亮,中看不中吃。 识别方法：有的蘑菇雪白透亮,粒土未沾,价格还便宜,很可能用漂白粉泡过的,中看不中吃。好的蘑菇生长在草灰里,难免会沾上草灰,而且正常蘑菇摸上去的手感有点黏糊糊的,漂白过的蘑菇摸上去只是光滑,不会有腻腻的手感。     

儿科医生告诉你：垃圾食品的N个真相

生活中。只要是新鲜的、没有污染的蔬菜、水果、肉类、主食。都是健康食品。然而,尽管健康食品足够我们选择。一些宝宝还是偏爱垃圾食品。不知不觉间。健康就受到了影响。     

“高大上”的食品添加剂

很多人对食品添加剂闻之变色,恨不得“零添加”。若是大家知道了有些食品添加剂的好处,可能还巴不得多加一点。     

食物减压，安全又轻松

董薇老师：您好!我爱人最近晋升职称,还有一个多月就要面对评委了,她似乎很紧张,最近总是有些丢三落四的。作为她的丈夫,只有做好家里的后勤保障,以支持她全力以赴实现自己的理望。我曾经想买些保健品给她吃,可朋友告诉我“药补不如食补”,有很多食品也可以帮助减轻心理压力,自己做,既安全又放心。请问有哪些食品是可以减压的？谢谢!     

菜场江湖

从前江南的菜市场,不分室内室外,布局似乎有默契。国营粮油商店列在进门处,店员们一脸铁饭碗表睛,闲散自在,时常串门。冷冻食品、豆制品这类带包装的,依在两旁;蔬菜水果市场交叠在入门处,殷勤叫卖;卖猪肉的分踞一案。虎背熊腰的大叔或膀阔腰圆的大婶们刀客般兀立,一派睥睨之态,俨然看不起蔬菜贩子们。卖家禽的常在角落,笼子里鸡鸭鹅交相辉映,真所谓鸡同鸭讲,看摊的诸位很淡定地坐在原地等生意,对空气里弥漫的家禽臭味毫无所觉。     

2013 年厦门市食源性致病菌监测结果

目的了解厦门市市售食品食源性致病菌污染情况,为控制和降低食源性疾病提供依据。方法根据（（2013年食源性致病菌工作手册》的要求,对采集的样品进行病原菌分离鉴定。结果共监测样品408份,检出致病菌22株,总检出率为5．39％,其中,铜绿假单胞菌检出率为20％（4／20）,阪崎肠杆菌检出率为12．5％（4／32）,副溶血性弧菌检出率为6．67％（5／75）。结论饮用水、婴幼儿食品、地方特色食品、餐饮食品和水产品是厦门市食品的主要污染品种,应加强监督管理,减少由此引起食源性疾病的发生。     

Blood-testis barrier and spermatogenesis： lessons From genetically-modified mice

The blood-testis barrier （BTB） is found between adjacent Sertoli cells in the testis where it creates a unique microenvironment for the development and maturation of meiotic and postmeiotic germ cells in seminiferous tubes. It is a compound proteinous structure, composed of several types of cell junctions including tight junctions （TJs）, adhesion junctions and gap junctions （GJs）. Some of the junctional proteins function as structural proteins of BTB and some have regulatory roles. The deletion or functional silencing of genes encoding these proteins may disrupt the BTB, which may cause immunological or other damages to meiotic and postmeiotic cells and ultimately lead to spermatogenic arrest and infertility. In this review, we will summarize the findings on the BTB structure and function from genetically-modified mouse models and discuss the future perspectives.     

Nasal mucosal inhalation of amyloid-beta peptide 3–10 defective adenovirus attenuates cytotoxicity induced by beta-amyloid(1–42)

Three-month-old Alzheimer's disease model transgenic mice were immunized with Aβ1–42, Plp-Adenovirus [Ad]-X-CMV-(Aβ3–10)10-CpG [AdCpG-(Aβ3–10)10] or AdCpG virus fluid via nasal mucosal inhalation, respectively. ELISA analysis of serum showed Aβ42 antibody titers were significantly increased in mice immunized with Aβ1–42 and AdCpG-(Aβ3–10)10. Concanavalin A and AdCpG-(Aβ3–10)10 stimulation significantly increased the number of proliferating spleen cells cultured from AdCpG(Aβ3–10)10 and Aβ42 groups compared with the control group. In the AdCpG(Aβ3–10)10 group, levels of interleukin(IL)-4 and IL-10 were increased, while those of IL-2 and interferon-γ were decreased. In the Aβ42 group, levels of IL-4, IL-10, IL-2 and interferon-γ were all increased. Experimental findings indicate that AdCpG-(Aβ3–10)10 vaccine can produce strong T helper 2(Th2) humoral immune responses in addition to the production of Aβ42 antibody. The cellular immunologic response was weak and avoided Aβ1–42-mediated cytotoxicity.     

Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice

Dopamine D1 receptors（D1Rs） play a key role in cocaine addiction, and multiple protein kinases such as GRKs, PKA, and PKC are involved in their phosphorylation. Recently, we reported that protein kinase D1 phosphorylates the D1 R at S421 and promotes its membrane localization. Moreover, this phosphorylation of S421 is required for cocaineinduced behaviors in rats. In the present study, we generated transgenic mice over-expressing S421A-D1 R in the forebrain. These transgenic mice showed reduced phospho-D1R（S421） and its membrane localization, and reduced downstream ERK1/2 activation in the striatum. Importantly, acute and chronic cocaine-induced locomotor hyperactivity and conditioned place preference were significantly attenuated in these mice. These findings provide in vivo evidence for the critical role of S421 phosphorylation of the D1 R in its membrane localization and in cocaine-induced behaviors. Thus, S421 on the D1 R represents a potential pharmacotherapeutic target for cocaine addiction and other drug-abuse disorders.     

国家卫生计生委办公厅关于印发国家卫生计生委食品安全相关行政许可评审专家管理办法的通知

各省、自治区、直辖市卫生计生委（卫生厅局）,新疆生产建设兵团卫生局,委直属有关单位：为规范新食品原料、食品添加剂新品种、食品相关产品新品种、进口无食品安全国家标准食品安全性审查和许可工作,根据《中华人民共和国食品安全法》、《卫生行政许可管理办法》的规定,我委组织制定了《国家卫生计生委食品安全相关行政许可评审专家管理办法...