内镜直视下幽门压力波的检测

报告了纤维胃镜直视下幽门压力波的检测方法,初步探讨了幽门压力波的特点,分类及其临床意义。该方法简便易行,准确客观,为临床诊断胃功能障碍和观察中药、针灸及其他治疗方法对胃运动功能的影响提供了一种新的研究手段。     

补肾通脉片治疗肾虚痰瘀型中风临床观察

以补肾通脉片治疗肾虚痰瘀型中风202例,并设西药对照组70例,按全国中风病协作组制订的疗效标准评定,结果表明,治疗组总有效率92.08％,对照组87.14％(P>0.05);总显效率治疗组60.40％,对照组37.14％(P<0.01),其中治疗组中急性期组、恢复期组总显效率分别优于对照组(P<0.01);语言功能恢复及患肢肩、髋关节功能恢复优于对照组(P<0.05)。     

周福生教授诊疗脂肪肝施治特色

本文旨在介绍周福生教授在运用中医药辨证施治脂肪肝的特色，周师认为脾虚失运，水湿停聚为其主要病机，治疗上应以健脾除湿、化痰泄浊，佐以活血为大法，同时配合合理饮食，加强体育锻炼，保持情志舒畅，只有全方位重视，才更有助于中医的辨证施治取得好的效果。     

The social–emotional development among children left behind by migrant mothers in rural China: a cross-sectional study

Background

Economic development and rapid urbanisation in China has caused parents to migrate to urban cities for jobs and to leave their children behind. The population of left-behind children has grown and requires attention, as early child development might be negatively affected by the lack of parental interaction. We therefore aimed to assess the specific influence of migrant mothers on early child development, especially on social–emotional problems.

基于数据挖掘技术总结难治性尿路感染的中医辨治规律

目的:基于数据挖掘技术探讨难治性尿路感染相关文献及医案的中医辨治用药规律。方法：在中国知网数据库中检索、下载难治性尿路感染相关文献,通过筛选、清洗、降噪处理及目标关键词频数统计的数据分层算法,挖掘难治性尿路感染的病因、病位、病机、主症、舌脉、证型、治法、方剂、中药规律,并进行可视化展示。结果：该病的病因、病机主要涉及正虚、邪实两端,证型以肾虚、膀胱湿热为主;治法以清热利湿兼补肾养阴为主;涉及的方药主要为补肾、清利类。结论：该研究应用数据挖掘技术对文献全文、病案处方进行系统、细致、分层次的总结。理、法、方、药诸层次的研究结果与临床实践对该病的认识有较好的一致性。     

陈可冀院士老年医学学术思想总结

本文对陈可冀院士在老年医学、心血管病防治、清宫医案整理等多方面取得的成果进行总结。陈老师基于全球人口老龄化的现状和我国丰富的老年医学理论和经验,形成了自己老年医学的研究特色和体系。陈老师建议对长寿老人进行社会性的调查研究,观察总结长寿的经验;并提出在长寿社会调查的研究思路和方法学上,需要进一步完善的问题,包括：明确调查对象和长寿的标准;结合中医老年病学理论和经验,应用多元分析方法,进行社会性考察,探索长寿规律,注意准确性。与临床治疗治疗相比,预防疾病和提高健康水平是有效控制衰老的更有效手段。对老年失能者,要建立多学科合作,社会、家庭、医疗机构共同参与的“大康复”机制。介绍了其通过对清代宫廷医案进行整理挖掘,优选出的一批清宫最为常用的方剂(包括食疗方),并证实了其在老年病的防治中具有很好的应用价值。阐述了陈院士对血栓性疾病病机的认识和治疗观念,并介绍了其在中西医结合治疗血管老化、冠心病及支架植入术后再狭窄、心衰等方面的经验。     

康欣口服液对老年小鼠睾丸超微结构的影响

目的 研究康欣口服液对老年Balb/c小鼠睾丸超微结构的影响。方法 Balb/c小鼠随机分为青年组、老年组和老年康欣口服液组,分别给予生理盐水和康欣口服液4个月,采用透射电镜观察小鼠睾丸超微结构。结果 青年组睾丸超微结构未见明显异常,老年组睾丸生精细胞明显减少,分裂异常,呈坏死脱落。支持细胞内线粒体肿胀,间质细胞内次级溶酶体明显增多。与老年组相比,老年康欣口服液组睾丸超微结构损伤有明显改善。结论 康欣口服液可改善老年小鼠睾丸超微结构损伤。     

Dynamic assessment of parathyroid function in acute malaria

Davis TME, Singh B, Choo KE, Ibrahim J, Sulaiman SA, Kadir ZA, Ismail R (University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia. Universiti Sains Malaysia, Kubang Kerian, Kota Bharu; General Hospital, Kota Bharu, Kuala Krai Hospital, Kuala Krai; Kelantan, Malaysia) Dynamic assessment of parathyroid function in acute malaria. J Intern Med 1998; 243 : 349–54.

Objectives

To investigate the dynamic parathyroid response to rapidly induced, sustained hypocalcaemia in patients with acute malaria and in healthy volunteers.

Design

Serum intact parathormone (PTH) concentrations were measured on samples taken before and during a variable-rate tri-sodium citrate infusion designed to ‘clamp’ the whole blood ionised calcium concentration 0.20 mmol L^?1 below baseline for 120 min.

Subjects

Six Malaysian patients aged 17–42 years with acute malaria, four of whom were restudied in convalescence, and 12 healthy controls aged 19–36 years.

Main outcome measures

Whole-blood ionised calcium and serum intact PTH concentrations.

Results

The mean (SD baseline ionised calcium was lower in the malaria patients than in controls (1.09 ± 0.06 vs. 1.18 ± 0.03 mmol L^?1, respectively; P= 0.01) but PTH concentrations were similar (3.0 ± 1.8 vs. 3.3 ± 1.3 pmol L^?1; P= 0.33). Target whole-blood ionised calcium concentrations were achieved more rapidly in the controls than the patients (within 15 vs. 30 min) despite significantly more citrate being required in the patients (area under the citrate infusion-time curve 0.95 (0.25 vs. 0.57 ± 0.09 mmol kg^?1; P < 0.01). The ratio of the change in serum PTH to that in ionised calcium (δPTH/δCa²⁺), calculated to adjust for differences in initial rate of fall of ionised calcium, was similar during the first 5 min of the clamp (132 ± 75 × 10^?6 vs. 131 ± 43 × 10^?6 in patients and controls, respectively, P > 0.05), as were steady-state serum PTH levels during the second hour (7.0 ± 2.2 pmol L^?1 in each case). Convalescent patients had normal basal ionised calcium levels but the lowest serum intact PTH levels before and during the clamp, consistent with an increase in skeletal PTH sensitivity after treatment.

Conclusions

There is a decreased ionised calcium ‘set point’ for basal PTH secretion but a normal PTH response to acute hypocalcaemia in malaria. Skeletal resistance may attenuate the effects of the PTH response but patients with malaria appear relatively resistant to the calcium chelating effects of citrated blood products.

     

周衡教授运用经方治病验案举隅

周衡教授致力于《金匮要略》研究50余年,湖南中医药大学资深教授,湖南省名中医．我国知名仲景学说研究专家,中国中医学会仲景专业委员会首任委员、顾问,享受国务院政府特殊津贴专家。挖掘、整理主校《金匮要略》首注本《金匮方论衍义》,并多次担任《金匮要略》全国教材编委及《中医药高级丛书·金匮要略》副主编,     

论《易经》《黄帝内经》中扶阳思想

《周易》存在明显的阳主阴从、贵阳贱阴思想,但比《周易》更早的《归藏易》和《连山易》皆不主扶阳。《归藏易》是黄帝易,重阴、重地道,与《周易》崇阳、重天道的思想,形成鲜明的对比。黄老道家主张致虚守静、清净无为、谦退守柔的思想,正与《归藏易》的精神相符。《黄帝内经》的哲学思想源自《归藏易》,渊源于黄老道家,故《内经》中亦无明显的扶阳倾向。扶阳派学者所称引的《内经》扶阳思想相关条文,实无明显扶阳倾向。