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G. Ducombs C. Benezra P. Talaga K. E. Andersen D. Burrows J. G. Camarasa A. Dooms-Goossens P. J. Frosch J. M. Lachapelle T. Menné R. J. G. Rycroft I. R. White S. Shaw J. D. Wilkinson 《Contact dermatitis》1990,22(5):249-252
6278 patients were patch tested with a sesquiterpene lactone mix (SL-mix) in 10 European clinics. 4011 patients were tested only with 0.1% SL-mix, 63 (approximately 1.5%) of whom were positive, with 26 (41%) of these cases being considered clinically relevant. There were no cases of active sensitization, though 5 cases of irritation were reported. 22 irritant reactions and 22 cases of active sensitization occurred when testing also with 1% and 0.33% concentrations of SL-mix. SL-mix 0.1% pet. is shown to be an important patch test and many relevant sensitizations will be missed without routine screening with such a mix. Most patients with SL-mix sensitivity presented with hand and/or face dermatitis, apparent photodermatitis or more generalised eczema. 相似文献
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目的:提高和完善平安丸的质量标准。方法:采用薄层色谱法对处方中母丁香、枳实进行了薄层色谱鉴别;采用高效液相色谱法对处方中木香的有效成分木香烃内酯、去氢木香烃内酯进行了含量测定。结果:薄层色谱斑点清晰、分离度好,阴性无干扰;木香烃内酯、去氢木香烃内酯进样量分别在0.103 4-1.033 5 μg(r=0.999 9),0.110 1-1.100 5 μg(r=0.999 7)范围内线性关系良好,平均回收率(n=6)分别为95.1%、98.6%,RSD分别为2.62%、2.84%。结论:本研究中的定性及定量方法简便准确、专属性强,能有效控制平安丸的质量。 相似文献
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