全文获取类型
收费全文 | 18714篇 |
免费 | 1680篇 |
国内免费 | 494篇 |
专业分类
耳鼻咽喉 | 106篇 |
儿科学 | 286篇 |
妇产科学 | 120篇 |
基础医学 | 2509篇 |
口腔科学 | 423篇 |
临床医学 | 2943篇 |
内科学 | 1513篇 |
皮肤病学 | 70篇 |
神经病学 | 3767篇 |
特种医学 | 708篇 |
外科学 | 901篇 |
综合类 | 2961篇 |
现状与发展 | 1篇 |
一般理论 | 16篇 |
预防医学 | 1819篇 |
眼科学 | 347篇 |
药学 | 1465篇 |
126篇 | |
中国医学 | 512篇 |
肿瘤学 | 295篇 |
出版年
2024年 | 96篇 |
2023年 | 863篇 |
2022年 | 1248篇 |
2021年 | 1526篇 |
2020年 | 1261篇 |
2019年 | 899篇 |
2018年 | 670篇 |
2017年 | 667篇 |
2016年 | 580篇 |
2015年 | 572篇 |
2014年 | 1132篇 |
2013年 | 1391篇 |
2012年 | 945篇 |
2011年 | 1097篇 |
2010年 | 772篇 |
2009年 | 778篇 |
2008年 | 851篇 |
2007年 | 771篇 |
2006年 | 727篇 |
2005年 | 556篇 |
2004年 | 459篇 |
2003年 | 397篇 |
2002年 | 339篇 |
2001年 | 267篇 |
2000年 | 252篇 |
1999年 | 182篇 |
1998年 | 199篇 |
1997年 | 192篇 |
1996年 | 123篇 |
1995年 | 96篇 |
1994年 | 82篇 |
1993年 | 88篇 |
1992年 | 63篇 |
1991年 | 56篇 |
1990年 | 54篇 |
1989年 | 33篇 |
1988年 | 56篇 |
1987年 | 33篇 |
1986年 | 31篇 |
1985年 | 54篇 |
1984年 | 55篇 |
1983年 | 37篇 |
1982年 | 42篇 |
1981年 | 34篇 |
1980年 | 36篇 |
1979年 | 32篇 |
1978年 | 25篇 |
1977年 | 36篇 |
1976年 | 31篇 |
1974年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
H. Condé 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1992,88(2):233-248
Summary A comprehensive review of the literature on the anatomy, electrophysiology and pharmacology of thesubstantia nigra is presented. A diagram is developed taking into account the interneuronal interactions of neurotransmitters and receptors that control firing rates and neurotransmitter releases. The central features of the diagram are a positive dopaminergic feedforward process and a positive feedback mechanism mediated by extrasynaptic substance P diffusing from striatal terminals to dopaminergic dendrites of thezona compacta neurons. This loop can enhance the transmission of information from thestriatum through thepars reticulata output neurons. The loop is controlled at the level of zona compacta neurons by a negative feedback supported by the dendritic release of dopamine and boosted by pedunculopontine activation mediated by muscarinic receptors. The output of the loop is controlled by two negative feedforward processes, both involving GABAergic striatonigral afferents. Application of the model to pharmacological studies of diverse behaviors including seizures, turning, and conditioned behaviors reveals unforseen relationships and may offer insights into, and directions for, further analysis of the mechanisms and functions involved. 相似文献
72.
Alison Prigg 《Australian Occupational Therapy Journal》2002,49(2):100-111
Occupational therapists provide support to children with special learning needs and their families during the child's transition from early childhood to mainstream school. Little has been documented regarding the role and experiences of occupational therapists working with children, families and teachers during transition in an Australian context. Six paediatric occupational therapists from one geographical area in New South Wales were interviewed and asked to relay their role and experiences when providing a service to children with special learning needs during their transition to school. Participants described their role to include: preparing the child for school; working with school personnel; and providing parental support. Although participants described both positive and negative experiences, among the negative experiences were: limited time to provide a service; recommendations to school personnel not being followed; school personnel not being supportive; feeling uncomfortable in the classroom; and limited involvement in planning. Participants described a role which is consistent with current school-based occupational therapy practice; however, in the participants' experience, there was a gap between the ideal service and what participants were able to provide. This included limited collaboration with teachers. 相似文献
73.
对构建特色医院文化的思考 总被引:3,自引:1,他引:2
21世纪的医院是文化的医院,21世纪医院的竞争是文化的竞争,谁能构建出具有特色的医院文化,谁就能赢得竞争主动权。构建特色医院文化,核心是形成共同的理想和精神支柱;关键是打造“学习型”医院组织;根本是树立以人为本、诚信求实的服务理念;目标是树立良好的医院形象;基础是加快医院信息化建设。 相似文献
74.
Tracy L. Veach Richard H. Rahe Robbyn L. Tolles Lynn M. Newhall 《Stress and health》2003,19(5):257-264
This study investigates the efficacy of an intensive, integrated approach to stress reduction and coping enhancement directed towards an educated, upper level management population. Ninety‐five US governmental senior managers participated in a 35‐h stress management retreat held over a 3.5‐day period. The retreat combined didactic and experiential activities that were designed to increase participants' knowledge of stress liabilities and coping skills. Participants were encouraged to make positive lifestyle changes and to create specific action plans for the year following the workshop. Evaluations of participant satisfaction were completed at the close of the workshop. Eighty‐three participants completed baseline and follow‐up Stress and Coping Inventory (SCI) assessments in order to identify durable changes in these measures. Across 10 months, participants showed significant improvements in their overall Global Balance scores, psychological symptoms, depression symptoms, and all major coping scales, including Health Habits, Social Support, Responses to Stress and Life Satisfactions. Therefore, an intensive, multifaceted approach to stress intervention is a viable option for encouraging sustained behavioural change. Copyright © 2003 John Wiley & Sons, Ltd. 相似文献
75.
The purpose of this study was to examine motor learning and retention given extensive practice in two fundamentally different movement sequences. One sequence was a memory-driven task (performing a series of whole body positions from memory) and the other a context-driven task (buttoning). Practice took place over 3 weeks, with performance measured weekly; retention was measured weekly for 3 weeks after practice. There were 7 people with Parkinson's disease (PD) and 7 age-matched neurologically healthy people who participated in this study. Both groups improved performance on both tasks with practice, with the majority of the change for the PD group occurring between 1 and 2 weeks of practice. Although those with PD did not necessarily perform as well as age-matched controls, they learned both sequences in a manner similar to age-matched controls, and exhibited retention across the 3-week retention interval. If people with PD are given sufficient practice they can learn and retain both memory-based and context-driven movement sequences as well as age-matched controls. The results provide support for maintaining physical activity and for intervention through movement therapy. 相似文献
76.
F. A. Ashley B. Gibson B. Daly S. Lygo Baker J. T. Newton 《European journal of dental education》2006,10(1):10-19
The aim of this study was to explore undergraduate and postgraduate dental students' understanding of a good learning experience by using 'reflection on learning' as described by Schon. Four groups of Year 4 BDS students and one group of postgraduate students in dental public health took part in a series of focus group discussions. The responses were grouped into four broad themes (a) active, practical and positive learning; (b) interactive/together learning; (c) personal learning; (d) theory into practice. Six educational models of good learning proposed by the students are described. 相似文献
77.
Stephen M Chadwick David R Bearn Alan C Jack Kevin D O'Brien 《European journal of dental education》2002,6(2):57-63
This paper explores some modern concepts of teaching and learning, including cognitive theory, the zone of proximal development, constructivism, andragogy and learning styles and describes how they have informed the development of an undergraduate orthodontic curriculum. The changes described include student-centred learning, guided self-learning, and the incorporation of problem-based learning concepts. The details of the problem-based learning programme are described together with results of student feedback on the change in teaching and learning style. 相似文献
78.
Research has demonstrated environmentally induced plasticity of hippocampal dentate gyrus-evoked potentials. Other research has shown a role of the NMDA receptor in dentate gyrus long-term potentiation (LTP). The authors tested the role of the NMDA receptor in one form of environmentally induced plasticity, in which transferring animals from their home cages to another environment results in significant excitatory postsynaptic potential (EPSP) enhancement and concomitant depression of the population spike. Rats were chronically implanted with stimulating electrodes in the perforant path and recording electrodes in the dentate gyrus bilaterally. Evoked potentials were recorded from freely behaving rats for four 20-minute sessions (1/wk), which took place immediately following an environmental transfer. Rats received 0.00, 0.05, 0.08, or 0.10 mg/kg MK-801 s.c. 30 minutes prior to recording sessions in either an ascending- or descending-dose series. Results showed that MK-801 produced a reduction of the EPSP enhancement, which takes place over the 20-minute session. The effects of MK-801 on spike depression varied as a function of dose series and time within a session, suggesting a long-term effect of MK-801 on spike depression. There was no detected effect of MK-801 on behavior. Results suggest a role of the NMDA receptor in this form of environmentally induced plasticity with different effects of NMDA receptor antagonism on EPSP enhancement and spike depression. 相似文献
79.
Heukrodt Carol; Powazek Morris; Brown Warren S.; Kennelly Denise; Imbus Charles; Robinson Herb; Schantz Stacy 《Journal of pediatric psychology》1988,13(2):223-236
The long-term effects of disease and treatment on electrophysiologicalmeasures of neurocognitive function were studied in childrenwho had survived acute lymphoblastic leukemia (ALL) for at least4 years and were currently in remission. We report here changesin cognitive processing time as shown by the latency of theP3 wave of the auditory event-related EEG potential (ERP). P3latency was significantly prolonged in long-term ALL surivors,as well as in patients successfully trreated for solid tumors(ST)outside the CNS who received similar chemotherapy but did notreceive prophylactic treatment to the CNS. P3 latencies werestrongly correlated with measures of school performance andIQ in these individuals. The similarity in P3 latency betweenthe ALL and ST groups suggests that the treatments used on thesepateints produce changes in electrophysiological responses thatare associated with mild, but significant, cognitive deficits. 相似文献
80.
Use of learned odor cues by newborn rats is critical for pup survival. Rat pups acquire approach responses to maternal odors through an associative conditioning mechanism. This learned behavioral response is accompanied by a modification of olfactory bulb neural response patterns to the learned odor. Both the behavioral and neural reponse changes involved and require norepinephrine release in the olfactory bulb. The source of this norepinephrine is the locus coeruleus. It is proposed that the unique response properties of the locus coeruleus during the early postnatal period in the rat may facilitate acquisition of these critical early memories. 相似文献