首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   10098篇
  免费   659篇
  国内免费   222篇
儿科学   63篇
妇产科学   287篇
基础医学   237篇
临床医学   1854篇
内科学   909篇
皮肤病学   10篇
神经病学   18篇
特种医学   153篇
外国民族医学   2篇
外科学   4348篇
综合类   1680篇
现状与发展   1篇
预防医学   377篇
眼科学   1篇
药学   598篇
  36篇
中国医学   96篇
肿瘤学   309篇
  2024年   22篇
  2023年   190篇
  2022年   330篇
  2021年   428篇
  2020年   472篇
  2019年   311篇
  2018年   307篇
  2017年   343篇
  2016年   460篇
  2015年   382篇
  2014年   768篇
  2013年   739篇
  2012年   643篇
  2011年   763篇
  2010年   623篇
  2009年   569篇
  2008年   449篇
  2007年   505篇
  2006年   432篇
  2005年   435篇
  2004年   319篇
  2003年   239篇
  2002年   207篇
  2001年   155篇
  2000年   126篇
  1999年   105篇
  1998年   83篇
  1997年   91篇
  1996年   110篇
  1995年   116篇
  1994年   107篇
  1993年   57篇
  1992年   34篇
  1991年   24篇
  1990年   9篇
  1989年   3篇
  1988年   4篇
  1987年   2篇
  1986年   7篇
  1985年   1篇
  1984年   2篇
  1982年   3篇
  1981年   2篇
  1979年   1篇
  1975年   1篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
IntroductionReduced port laparoscopic surgery using an umbilical zigzag incision is comparable to conventional multiport laparoscopic surgery. This method is associated with improved cosmesis and decreased wound pain.Presentation of caseA 67-year-old man visited our hospital. He presented emergency room with a chief complaint of right lower abdominal pain by walking. The patient was diagnosed Meckel’s diverticulitis by computed tomography (CT). At first, antibiotics therapy and fasting were performed. Three months later, the patient underwent resection of Meckel’ diverticulum with zigzag transumbilical laparoscopic surgery. The patient’s postoperative course was good, and he rarely felt wound pain. The patient started oral intake three days after surgery, and was discharged 10 days after surgery.DiscussionZigzag transumbilical laparoscopic surgery is very useful for resection of the small intestine. This method is associated with improved cosmesis and decreased wound pain. In the case of Meckel’s diverticulitis, we suggest that interval resection of Meckel’s diverticulum was very useful as it was an operation that could be performed easily.ConclusionReduced port laparoscopic surgery using an umbilical zigzag incision is considered to be an excellent technique in terms of operability and aesthetic outcomes.  相似文献   
62.
目的 研究妇科腹腔镜术后深静脉血栓的发生率。方法 在澳大利亚悉尼Liverpool医院 1997年 5月~ 1997年 9月 72例妇科腹腔镜手术采用Doppler超声检查静脉血流的通畅性和血管腔内的回声团用以诊断深静脉血栓。 61例患者充气时间 <60分钟为小手术组 ,11例 >60分钟为大手术组。每例患者在术后 2 4小时内及术后 7天行两次超声Doppler检查 ,所有 72人均行术后 2 4小时内的超声Doppler检查 ,小手术组 61例中 4 0例、大手术组 11例中 9例行二次超声检查。 2 3例未行二次超声检查者均行电话随访。结果 在我们的研究中两组患者均未发现DVT。本文同时报道北京复兴医院一例腹腔镜下右卵巢巧克力囊肿剥除术、左卵巢及部分输卵管切除术患者术后并发DVT ,其诊断及治疗经过。结论 这项研究证实妇科腹腔镜手术DVT虽发生率极低 ,一旦发生需及时诊治 ,以免发生肺栓塞等致命并发症。  相似文献   
63.
为观察异丙酚全凭静脉麻醉在老年人腹腔镜胆囊切除术 (LC)围麻醉期呼吸循环功能的变化 ,以评价其实用性和安全性 ,将 30例ASAⅠ~Ⅱ级患者 ,择期行LC手术 ,以微量泵持续静注异丙酚维持麻醉 (剂量递减法 10~ 8~ 6mg/kg·h-1) ,控制呼吸频率 16~ 2 5 /min ,人工气腹后保持轻度过度通气状态 ,连续监测呼吸循环功能各参数的变化。结果显示 :本组异丙酚平均总用量为 5 6 0± 12 8mg( 8.0 5± 2 .16mg/kg·h-1) ,麻醉诱导后SBP、DBP、MAP一过性降低 (P <0 .0 1) ,于插管后迅速恢复 ;CO2 气腹后PETCO2 开始上升并于 15min后达最高值但在正常范围 ,86 .6 7%的病例于拔管后 5~ 10min麻醉苏醒并能简单答话。认为异丙酚全凭静脉维持麻醉用于老年人LC并于气腹期轻度过度通气能维持呼吸循环功能的相对稳定 ,且苏醒快 ,术后恢复良好 ,具有实用性和安全性  相似文献   
64.
目的探讨腹腔镜胆囊切除术(LC)中导致中转开腹的危险因素。方法将122例患者分为LC成功组115例和中转开腹组7例,分析其年龄、最高体温、既往发作史、发作至手术时间、白细胞计数、血清总胆红素、碱性磷酸酶、胆囊肿大、胆囊坏疽、胆结石大小、胆囊颈结石嵌顿对中转开腹的影响。结果中转组7人均为胆囊炎发作72h之后手术,与成功组的23/115(20%)相比,有极显著性差异(P<0.01)。中转组既往发作均超过10次,而成功组中仅有27人(23%)发作超过10次,两组之间有极显著性差异(P<0.01)。术前最高体温、白细胞计数、血清总胆红素、碱性磷酸酶、胆囊积脓以及胆囊结石大小在两组间均无显著性差异(P>0.05)。胆囊肿大超过10cm、胆囊颈结石嵌顿使中转开腹率大大提高,两组间有显著性差异(P<0.05,P<0.01)。结论年龄大于65岁的急性胆囊炎患者,既往发作超过10次,本次发作超过72h,术前B超示胆囊肿大超过10cm,胆囊颈结石嵌顿时,应直接选择开腹胆囊切除术。  相似文献   
65.
多区域浸润麻醉减轻腹腔镜胆囊切除术后早期症状   总被引:1,自引:0,他引:1  
目的探讨躯体、内脏局部浸润麻醉对择期腹腔镜胆囊切除术后疼痛、恶心症状的影响.方法随机将50例病人分为对照组和实验组,在门静脉周围和腹膜内分别浸润生理盐水66ml和罗吡卡因66ml;术后3h记录疼痛和恶心的程度、部位及所补充的哌替啶用量.结果罗吡卡因局部浸润可减轻术后3h的切口疼痛和恶心症状,但对腹内和肩部疼痛无明显效果;且术后3h所补充的哌替啶的用量显著减少.结论躯体、内脏局部浸润麻醉可减轻术后3h的切口疼痛、恶心及哌替啶用量.  相似文献   
66.
Interleukin-6 (IL-6) levels have been shown to correlate well with the magnitude of surgical stress. Serum IL-6 and plasma granulocytic elastase levels, 24 h after surgery, were determined in 12 patients who underwent open major surgery [MS group; esophageal carcinoma (n=5), gastric carcinoma (n=3), colorectal carcinoma (n=4) 5 patients who had open cholecystectomy [OC group] and 17 patients who had laparoscopic cholecystectomy [LC group]. IL-6 levels correlated significantly with the duration of surgery (r=0.685,P < 0.01) and with intraoperative blood loss (r=0.583,P < 0.02). However, there was no significant correlation between granulocytic elastase and the duration of surgery or blood loss. Plasma IL-6 levels in the LC group (21±3 pg/ml) were significantly lower than those in the OC group (47±5 pg/ml) and the MS group (186±36pg/ml) (P<0.05;P<0.01). However, there was no significant difference in granulocytic elastase levels between the LC group (318±8g/l), the OC group (360±130 gmg/ml), and the MS group (701±344 g/l). Increased IL-6 levels correlated well with increased duration of surgery. The lower IL-6 levels following laparoscopic cholecystectomy may therefore be indicative of lower surgical stress associated with laparoscopic cholecystectomy.  相似文献   
67.
We evaluated 81 women with adnexal adhesions and no male factorwho underwent microsurgical (n = 59) and laparoscopic (n = 22)adhesiolysis for infertility. The cumulative conception ratesfor all 81 patients at 12 and 24 months were 41 and 44% respectively.The impact of the following variables on cumulative conceptionrates for all patients was examined: age, duration of infertility,type of infertility, ovulatory status, presence and stage ofendometriosis, adhesion grade, adnexal status (bilateral orunilateral disease, unilateral tubal absence), history of previoussurgery, history of pelvic inflammatory disease and treatmentmodality (microsurgical versus laparoscopic). The results ofindependent comparisons of subgroups within each of these variablesmay be biased because of the interrelationships between thevariables. To overcome this problem, a stepwise Cox's proportionalhazards regression analysis was employed. Our analysis showedthat the single most significant variable influencing the cumulativeconception rates was the duration of infertility (P < 0.005).For every additional year of infertility, the probability ofpregnancy after adhesiolysis (microsurgical or laparoscopic)was reduced by 20%. Cumulative conception rates at 12 and 24months after microsurgical adhesiolysis were 36 and 40% respectively,while after laparoscopic adhesiolysis they were 57% at 12 and24 months. When imbalances were adjusted between the two treatmentgroups, there was no statistically significant difference betweenthe cumulative conception rates for microsurgical and laparoscopicadhesiolysis.  相似文献   
68.
Since March 1991 a monthly course on laparoscopic cholecystectomy has been organized at the Department of Surgery of the University of Turin. To evaluate the impact of this course and to obtain feedback from surgeons in order to improve the teaching of laparoscopic surgery, detailed questionnaires were sent to the participants of the first 20 courses.The outcome of this survey shows that short-residency hands on courses do not represent a completely satisfactory training, either for practicing surgeons or for residents, mainly because of the constraints of time and the lack of proctoring and supervision. Besides, the present study shows a significant difference in the diffusion of laparoscopic surgery in different areas of Italy.However, clinical results reported by this group of surgeons are satisfactory and comparable to the best multicentric series: 2,127 laparoscopic cholecystectomies were performed by 48 surgeons with a conversion rate of 6% and a complication rate of 2.4%.  相似文献   
69.
Fundus-first laparoscopic cholecystectomy   总被引:1,自引:1,他引:0  
Removal of the gallbladder with commencement of dissection at the fundus is well recognized as a safe technique during difficult open cholecystectomy because it minimizes the risks of damage to the structures in or around Calot's triangle. We report here the routine employment of liver retractors and fundus-first dissection during laparoscopic cholecystectomy (LC) as an alternative to techniques previously described.Retraction of the liver and fundus-first dissection was used in 53 patients who underwent laparoscopic cholecytectomy. There were 16 male and 37 female patients. Seven were operations performed during an acute admission and 20 had moderate or severe adhesions involving the gallbladder. Thirteen patients had a preexisting abdominal incision.The procedure was successful in 52 patients (98%), but in one patient it was converted to open operation because of dense adhesions. Median duration of operation was 90 min (range 35–240 min). There was no mortality and two complications (persistent right upper quadrant pain for 2 weeks after operation and bile leakage from the gallbladder bed).The facility to retract the liver and carry out a fundus-first dissection extends techniques developed for open surgery into the laparoscopic arena. It offers the surgeon the safety and versatility during laparoscopic cholecystectomy that it confers during conventional open surgery.Presented at the annual meeting of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Nashville, Tennessee, USA, 18–19 April 1994  相似文献   
70.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号