Enhanced Ultraviolet Damage Resistance in Magnesium Doped Lithium Niobate Crystals through Zirconium Co-Doping

MgO-doped LiNbO₃ (LN:Mg) is famous for its high resistance to optical damage, but this phenomenon only occurs in visible and infrared regions, and its photorefraction is not decreased but enhanced in ultraviolet region. Here we investigated a series of ZrO₂ co-doped LN:Mg (LN:Mg,Zr) regarding their ultraviolet photorefractive properties. The optical damage resistance experiment indicated that the resistance against ultraviolet damage of LN:Mg was significantly enhanced with increased ZrO₂ doping concentration. Moreover, first-principles calculations manifested that the enhancement of ultraviolet damage resistance for LN:Mg,Zr was mainly determined by both the increased band gap and the reduced ultraviolet photorefractive center O^2−/−. So, LN:Mg,Zr crystals would become an excellent candidate for ultraviolet nonlinear optical material.     

根据大型复合低压舱特点完善操作规程设计

目的：根据大型复合低压舱的特点,制定出切合实际、可操作性强的操作规程,确保大型复合低压舱能够长期安全稳定运行。方法：通过手动和自动控制,试运行具有低压、低温、高温、干燥和紫外线消毒功能的大型复合低压舱,实现单项功能和组合功能,探究其运行特点,找寻最佳方案,完善操作规程。结果：（1）完善了大型复合低压舱模拟高寒环境功能的操作规程;（2）完善了大型复合低压舱模拟低压环境时,多舱联合使用及备用泵使用的操作规程;（3）完善了大型复合低压舱5大功能组合模拟复合自然环境的操作规程;（4）完善了大型复合低压舱真空泵使用和保养的操作规程。结论：根据大型复合低压舱特点,完善了操作规程,使实验舱各项功能的实现更加科学、更加安全稳定。     

键盘、鼠标灭菌仪的研制

目的：设计并研制一种键盘、鼠标灭菌仪,对键盘、鼠标等常用电子设备表面的常见细菌进行有效杀灭,从而改善计算机的鼠标和键盘的卫生状况。方法：该仪器主要利用电子电路来控制紫外线灯管发射的特定波长紫外线．发射的紫外线能够破坏和改变细菌的脱氧核糖核酸（DNA）的结构,使细菌当即死亡或不能繁殖后代。结果：该灭菌仪能够有效杀灭键盘和鼠标等电子设备的常见细菌,避免细菌在公用计算机（网吧、电子阅览室等场所的计算机）上的传播与交叉感染。结论：该灭菌仪实用性好,可普及性强．有效改善了公用计算机的卫生状况。     

窄谱UVB联合中医治疗副银屑病的疗效分析

目的:分析窄谱UVB联合中医治疗副银屑病的疗效。方法:回顾性研究笔者科室门诊在2006年1月~2013年1月治疗的副银屑病患者共32例,将患者随机分为治疗组和对照组各16例,两组患者均采用干扰素300万U进行基础治疗。对照组采用单纯中医方法治疗;治疗组采用窄谱中波紫外线(UVB)联合中医方法治疗。治疗过程中观察患者的临床症状,疗程完成后对患者的临床疗效进行评判。结果:治疗组痊愈12例,显效3例,有效1例,无效0,对照组痊愈4例,显效4例,有效6例,无效2例。两组患者的临床疗效比较,差异有统计学意义(P0.05)。治疗组患者有3例发生皮肤红斑症状,对照组有2例出现胃肠道不适反应,未经特殊治疗后缓解,未影响正常治疗。两组患者的不良反应发生率差异无显著性(P0.05)。结论:窄谱UVB联合中医治疗副银屑病疗效较好,安全、可靠,其远期效果及并发症需进一步加大样本研究。     

窄谱中波紫外线联合复方甘草酸苷治疗斑秃疗效观察

目的 探讨窄谱中波紫外线（NB-UVB）联合复方甘草酸苷治疗斑秃的疗效及机制。方法 将73例斑秃患者随机分为联合组37例和药物组36例,另选37例健康查体者作为对照组。药物组及联合组均口服复方甘草酸苷50 mg,3次/d,联合组在此基础上行NB-UVB照射治疗,治疗3个月后判定两组疗效。采用流式细胞仪检测三组治疗前后外周血CD3^＋、CD4^＋、CD8^＋及CD4^＋/CD8^＋细胞水平变化。结果 联合组及药物组有效率分别为91.9%、71.2%,P〈0.05。治疗前联合组及药物组CD3^＋、CD4^＋及CD4^＋/CD8^＋水平均明显低于对照组,P均〈0.05;治疗后联合组及药物组CD3^＋、CD4^＋及CD4^＋/CD8^＋均明显高于治疗前（P均〈0.05）,CD8^＋水平无明显变化;联合组CD3^＋、CD4^＋及CD4^＋/CD8^＋明显高于药物组（P〈0.05）,CD8^＋无明显变化。结论 斑秃患者免疫功能存在异常,NB-UVB联合复方甘草酸苷治疗斑秃疗效确切;其机制可能为改善患者的免疫功能。     

紫外线灯的小改进

临床中经常采用紫外线灯进行空气及物体表面的灭菌,具有使用方便、无毒、无损等优点,适于空气、物体表面及一些不能干热或受湿的物品等灭菌,在医院中得到广泛应用。实际工作中我们通过对紫外线灯加装-改进的反光罩,获得较好的使用效果。现介绍如下。材料紫外线灯1个,1mm厚的光学平面反光镜(或薄铝板、不锈钢薄板)1块,槽形铝合嵌金1根,螺钉数枚,玻璃刀。方法用玻璃刀将反光镜划成与紫外灯架等长,宽为5cm的大小,再用铝合金槽将其四周嵌合,用螺钉将其固定于紫外线灯后的灯架上即成一反光罩(反光面朝向灯),从而加强紫外线的反射。直接用铝板或不…     

Predicting the different progressions of early pressure injury by ultraviolet photography in rat models

Early pressure injury (PI) can result in either spontaneous healing (SH) or deterioration into ulcer (DU). However, determining whether PI will progress into SH or DU on the basis of non‐blanchable erythema only is difficult. In this study, we constructed two animal PI models to mimic SH and DU injuries and observed haemorrhage by using ultraviolet (UV) photography to develop potential clinical indicators for predicting the progression of early PI. Macroscopy, UV photography, and skin temperature observations were obtained. In the SH group, macroscopic observation showed the erythema was obvious at 0.5 hours after decompression and faded gradually had almost disappeared at 72 hours. In the DU group, the erythema persisted, and an erosion appeared at 24 hours after decompression and expanded at 36 hours. The erythema developed into an obvious ulcer at 48 hours and enlarged at 72 hours. The obvious ulcer found at 48 hours through macroscopic observation was clearly visible at 36 hours with UV photography, and a significant difference in grey values between the two groups was found at as early as 18 hours (P < .05). This study provided evidence showing that UV photography can predict the different progression stages of early PI. Additionally, when combined with the transparent disc method, UV photography also can be used to identify the circulatory disorders of early PI, such as haemorrhage or hyperaemia and even congestion.     

Resveratrol Inhibits Secretion of Interleukin 8 by Regulation of Autophagic Flux in Ultraviolet B-stimulated Keratinocytes

Objective:The plant polyphenol resveratrol(3,4',5-trihydroxystilbene)(RSV)has been proposed for use because of its protective effect on ultraviolet(UV)-induced ...