多电极射频治疗肝肿瘤安全性和有效性分析

目的:探讨多电极射频(RF)对肝肿瘤治疗的安全性和有效性。方法:对47例肝癌(42例原发性癌,5例转移性癌)采用B超引导下RF治疗,并前后影象及AFP数值观察。结果:本组无严重并发症或死亡者.80%患者术后自觉症状明显改善,50%的AFP值下降。术后30d80%的肿瘤体积缩小30%;术后60d,30%瘤体缩小50%。结论:多弹头射频治疗是治疗肝癌安全和可靠的方法。     

射频联合抑酸剂加抗反流药治疗Barrett食管的临床观察

目的:观察射频联合抑酸剂加抗反流药治疗Barrett食管的临床疗效。方法:对35例经内镜和病理确诊的Bar-rett食管病人,分别采用射频联合质子泵抑制剂、多潘立酮(治疗组)和质子泵抑制剂、多潘立酮(对照组)治疗,于用药和射频末次治疗后第3、6个月进行内镜和病理复查。结果:治疗组20例总有效率分别为35%、77.78%,而对照组则分别为0、15.38%(P<0.01)。治疗组除出现短暂胸骨后疼痛、吞咽疼痛、低热外,无出血、穿孔等并发症。结论:射频联合抑酸剂加抗反流药治疗Barrett食管疗效确切。     

经鼻内窥镜射频治疗鼻咽癌放疗后鼻后孔闭锁

目的探讨鼻咽癌放疗后鼻后孔闭锁的治疗方法。方法对鼻咽癌放疗后鼻后孔闭锁8例采用经鼻内窥镜切除纤维瘢痕后射频处理创面，并置入橡皮管扩张。结果全部病例随访1-4a，无1例再次出现鼻后孔闭锁，双侧鼻腔通气良好。结论鼻内窥镜下射频治疗鼻咽癌放疗后鼻后孔闭锁具有术式简单，术野清晰，创伤小，疗效良好等优点，是治疗鼻咽癌放疗后鼻后孔闭锁的最佳手术方法。     

术中超声在冷循环射频治疗肝脏肿瘤中的作用

目的:探讨术中超声在冷循环射频治疗肝脏肿瘤中的应用价值。材料和方法:对31例肝癌患者在开腹手术时行术中超声检查,并以超声作为射频针穿刺的引导手段,动态观察手术进程。结果:31例患者均在术中超声引导下完成治疗。其中7例术前未发现小病灶。1例排除术前MR I诊断的1处假阳性病灶。结论:术中超声可发现术前影像学检查遗漏的小病灶,避免胆管、血管损伤等并发症,实时观察射频治疗过程并优化手术策略。     

Transcatheter retrograde radio-frequency perforation of the pulmonic valve in pulmonary atresia with intact ventricular septum,using a 2 French catheter

A neonate with pulmonary atresia with intact ventricular septum (PA/IVS) underwent successful retrograde transcatheter perforation of the pulmonary valve, using a 2 Fr radio-frequency catheter with subsequent anterograde balloon dilation of the valve. Due to persistent hypoxemia, the neonate underwent placement of a 4-mm modified Blalock-Taussig shunt. Transcatheter retrograde transductal perforation of the pulmonic valve in PA/IVS is feasible and may be a potential alternative to anterograde perforation. Cathet. Cardiovasc. Diagn. 45:151–154, 1998. © 1998 Wiley-Liss, Inc.     

原发性肝癌的射频治疗效果分析

目的 分析原发性肝癌患者接受射频消融治疗的近期疗效及并发症.方法 分析2006年6月到2009年6月接受以射频消融为初始治疗并获得随访的85例原发性肝癌患者的临床资料.选择同期手术切除肿瘤最大径小于5cm并获得随访的103例肝癌患者作为对照组.结果 RFA组85例共106个瘤体均进行消融,术后1年有7例局部肿瘤进展,9...     

肝动脉化疗栓塞联合射频消融治疗中晚期肝癌的临床疗效分析

目的：评价联合应用肝动脉化疗栓塞和经皮射频消融治疗中晚期肝癌的临床应用价值。方法：经病理、AFP或影像学证实的符合标准的中晚期肝癌112例,按治疗方法随机分为单纯肝动脉化疗栓塞组（TACE）和TACE＋射频消融组（RFA）。TACE组54例,TACE＋RFA组58例。结果：TACE组治疗有效率为44%,联合治疗的有效率为68%,两组间差异有统计学意义（P〈0.01）;TACE组患者1年、2年和3年生存率分别为85%、64%和23%,中位生存期1.725年,联合介入治疗组患者1年、2年和3年生存率分别为93%、88%和79%,中位生存期为2.296年。联合介入治疗组的生存率及生存期显著高于TACE组（P〈0.05）。结论：联合应用肝动脉化疗栓塞和经皮射频消融治疗可显著提高中晚期肝癌患者的生存率,延长生存期。     

鼻内镜联合低温射频等离子消融治疗并有鼻中隔偏曲变应性鼻炎的疗效分析

目的探讨鼻内镜联合射频等离子消融治疗并有鼻中隔偏曲变应性鼻炎的手术治疗方法及其疗效。方法对40例并有鼻中隔偏曲变应性鼻炎的患者,应用鼻中隔次全成形术治疗鼻中隔偏曲,低温射频等离子对肥大鼻甲、鼻丘及鼻中隔前上方消融治疗。结果 40例患者均能在局麻下完成治疗,随访1年以上,该方法能矫正鼻中隔偏曲,有效的缩小肥大鼻甲,术后患者术后过敏症状消失,有效率达97.5%,无并发症发生。结论鼻内镜联合低温射频等离子消融治疗并有鼻中隔偏曲变应性鼻炎效果明显、创伤小、安全,有较好的临床应用价值。     

射频波治疗前列腺肥大

射频波具有波长长、穿透能力强,在生物组织中热效应深透、均匀、持续时间长的特点,被临床应用于前列腺炎、增生、肥大等病人,收到良好效果。     

Acute Electrophysiologic Effects and Antifibrillatory Actions of the Long Linear Lesions in the Right Atrium in a Sheep Model

Linear lesions (LL) represent an option for curing of atrial fibrillation (AF) with ablation techniques.Methods and Results: In 11 sheep (w. 72±16[emsp4 ]kg), LL were created with radiofrequency ablation in the lateral, posterior and septal walls of the right atrium (RA). AF was induced before and after LL with burst pacing. Mapping of the AF was performed with a 64-electrode basket catheter deployed in the RA. Quantitative analysis was performed with a custom-made software program. LL were confirmed histologically 7 to 10 days after the procedure. LL were transmural in 78% of their length. Stimulation thresholds and right atrial activation times were increased after LL compared to preablation values. Effective refractory periods of the RA were prolonged significantly in 7 out of 12 regions after generation of LL. Conduction velocities in the RA segments between LL were reduced in lateral, posterior and septal walls. During paced rhythms double potentials were recorded in all animals. AF could be induced in all animals of this model despite the presence of LL in the RA. AF episodes were significantly more regular after LL throughout the RA due to a significant reduction of the number of the wave fronts in the RA. During AF episodes, in the presence of LL, the RA was driven by wave fronts of left atrial origin entering the right side of the septum through interatrial connections.Conclusions: 1) LL profoundly affect electrophysiologic parameters of RA. 2) In the presence of LL, AF manifest a higher degree of regularity as compared to preablation episodes. 3) Dissociation between wave fronts of left atrial origin entering the RA through the interatrial connections is an important mechanism of the antifibrillatory action of the septal LL.