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71.
产程延长传统处理方法是应用催产素静脉点滴,根据安定能选择性使宫颈肌纤维松驰;东莨菪碱能扩张血管,改善微循环,解除平滑肌痉挛,使宫颈水肿消失或减轻,我院妇产科自1988年5月至1989年4月,对176例在产程延长或宫颈水肿的产妇,联合应用安定、东莨菪碱,取得良好的效果,本文介绍了应用方法,并对二药的药理作用进行了讨论。 相似文献
72.
N. F. Wieringa A. H. R. de Meijer M. D. B. Schutjens R. Vos 《Social science & medicine (1982)》1992,35(12):1497-1504
The market of non-registered pharmaceutical products is growing fast in number and overall costs, not only in the Netherlands, but also in other European countries. These products often give the impression that the consumer may expect 'an effect as from a drug'. Legally, there is a clear distinction between 'drugs' and 'commodities' in the Netherlands; the question is whether legislation and practice concur. In an investigation we analysed texts of advertisements for non-registered pharmaceutical products published in a popular magazine. A method was developed, based on the legal definition of a drug and jurisprudence, to determine in a qualitative and quantitative way the application of medicinal claims. It transpired that in 65% of the analysed advertisements explicit or implicit claims were made. These products should therefore be subject to drugs legislation. Thus, in the Netherlands there is a gap between legislation and practice in advertising non-registered pharmaceutical products. 相似文献
73.
This brief review provides an overview of this topic; it is not a critical review. Polydrug use is a poorly defined concept; it is taken here to mean the simultaneous use of more than one drug. Data on polydrug use is seldom systematically collected, and the use of alcohol and tobacco in combination with illegal drugs is frequently overlooked. If alcohol and tobacco are included, most users are polydrug users, since these drugs are used by most users of illegal drugs, and many people with alcohol problems also use illegal drugs. Polydrug use has increased; drug availability, cultural context and the 'normalization' of drug use are important factors. Gender and racial differences are observed in the prevalence of polydrug use. Implications for drug prevention include the importance of targeting multiple substance use rather than single substances. Aiming prevention campaigns at younger people and focusing on 'gateway' drugs might be more effective. But polydrug users are diverse, and a variety of strategies (aimed at different types of polydrug users) are necessary. Implications for treatment include the evidence of the greater difficulty that polydrug users have in quitting; they may therefore require additional help. A fuller, systematic, review is required; it is expected that this would recommend the commissioning of additional research on this poorly understood phenomenon. 相似文献
74.
目的:评价卡维地洛联合螺内酯对老年难治性高血压的临床疗效及安全性,以指导临床工作。方法:老年难治性高血压患者200例分成两组,观察组(120例)经安慰剂洗脱2周后口服卡维地洛配伍螺内酯治疗,对照组(80例)在原有用药基础上加用螺内酯,治疗后共观察8周,探讨疗效。结果:观察组不良反应发生少,且观察组总有效率明显高于对照组,观察组对改善左心室射血分数和左心室舒张末期内径效果明显。结论:卡维地洛联合螺内酯对老年难治性高血压控制较好,并能改善心室结构,临床应用效果好。 相似文献
75.
手术配合局部外用药治疗慢性肛门湿疹临床观察 总被引:2,自引:0,他引:2
目的:观察手术配合术后曲咪新加复方鱼肝油软膏混合膏局部换药治疗慢性肛门湿疹的疗效.方法:将93例慢性肛门湿疹患者随机分为治疗组(47例)和对照组组(46例),治疗组采用手术配合术后曲咪新加复方鱼肝油软膏混合膏局部换药,对照组采用亚甲蓝局部封闭配合术后皮炎平局部换药.观察两组患者术后长短期疗效.结果:治疗组短期有效率为93.61%,疗效优于对照组71.74%(P<0.01);治疗组远期有效率为89.36%,优于对照组60.87%(P<0.01).结论:本法治疗慢性顽固性肛门湿疹疗效确切、复发率低. 相似文献
76.
活血化瘀中药联合血管内皮生长因子基因转移促进股骨头坏死处新生血管形成的实验研究 总被引:5,自引:4,他引:1
目的:观察活血化瘀中药联合血管内皮生长因子(VEGF)基因转移对促进股骨头缺血坏死处新生血管形成情况。方法:日本大耳兔40只,随机分为对照组、模型组、中药组、基因组和综合组。治疗8周后采用免疫组织化学方法观察股骨头滑膜VEGF阳性细胞率及数字减影血管造影股骨头血管数目改变情况。结果:模型组VEGF阳性细胞表达率减低,与对照组、基因组、综合组比较,差异有显著性意义(P<0.01),与中药组比较,有统计学差异(P<0.05),综合组VEGF阳性细胞表达率较高,与中药组及基因组比较,有统计学差异(P<0.05)。血管数目:在A区,各组与模型组比较,均无统计学差异;在B区,各组较模型组血管数目均有增加,对照组、基因组、综合组与模型组比较,有统计学差异(P<0.05)。综合组与基因组比较有统计学差异(P<0.05),中药组虽然血管数目较模型组多,但是无统计学意义。结论:活血化瘀中药及VEGF基因转移均可促进股骨头缺血坏死处局部新生血管形成和侧支循环的建立,尤以活血化瘀中药联合基因疗法效果为好,为临床应用活血化瘀中药联合基因疗法治疗股骨头缺血性坏死提供实验依据。 相似文献
77.
Jonathan Appel Dohee Kim-Appel 《International journal of mental health and addiction》2007,5(3):248-253
Since the 1990s, there has been a rise in the availability and recreational use of a herbal plant called Salvia divinorum. Numerous internet websites have advertised it for sale as a legal herbal alternative to illegal hallucinogens. Initial data
surveying use has indicated many young adults are obtaining and using this herb for its psychoactive properties. Reported
methods of ingestion for the plant include chewing, and smoking leaves or fortified extracts. Subjective effects of the plant
include, affect changes, psychedelic-like changes in perception, and even loss of consciousness. Although the pharmacological
properties and possible antidepressant effects have been studied in recent years, little information is known about potential
negative impact resulting from recreational use, and scant information about Salvia divinorum currently exists in the psychological
and substance abuse literature. While Salvia divinorum appears to be a substance with some therapeutic potential, it also
poses some significant dangers as a substance of varying legal status with a potential for abuse. 相似文献
78.
①目的 观察中药醇提物 (HD组方 )对血液透析效果的影响。②方法 选择我院终末期肾衰竭 (ES RD)病人 6 6例 ,已行维持性血液透析治疗 1年以上 ,随机分为常规组 32例 ,中药组 34例。常规组继续进行常规血液透析 ,中药组在常规透析的基础上 ,将透析液中加入HD组方 ,疗程均为 6个月。定期观察各组病人透析前、后血清尿素氮 (BUN)、肌酐 (Cr)、平均时间尿素氮浓度 (TACurea)、蛋白分解率 (PR)及G S指数 (KT/V值 )。③结果 中药组治疗后BUN、Cr水平与常规组同期比较明显降低 ,差别具有显著性 (t=2 .5 6 1、2 .4 98,P <0 .0 5 )。中药组治疗后TACurea较治疗前明显降低 ,差别具有极显著性 (t=2 .797,P <0 .0 1 ) ;而PR、KT/V值较治疗前明显升高 ,差别具有显著性 (t=2 .36 1、2 .4 98,P <0 .0 5 )。④结论 中药HD组方在透析液中的应用可提高ESRD病人透析效果及生活质量 相似文献
79.
M. Cioni I. Iero G. Tornatore A. Cocilovo A. Belfiore R. Ferri 《Neurological sciences》2007,28(2):100-103
Abstract We describe kinematics, kinetics and electromyographic patterns of a patient with spinal myoclonus of the left lower limb,
during walking. Gait analysis was performed when the patient was OFF and ON his treatment with antiepileptic drugs. When OFF,
we mainly observed clonic bursts and out-of-phase activations of m. tibialis anterior and m. rectus femoris, with increased
hip flexion, reduction of knee flexion during swing and excessive ankle dorsal flexion. Furthermore, large oscillations of
knee moment of force and power during stance phase were also observed. These abnormal patterns markedly recovered when ON
drugs. 相似文献
80.
V. Belcastro C. Costa F. Galletti F. Pisani P. Calabresi L. Parnetti 《European journal of neurology》2007,14(10):1176-1178
Levetiracetam (LEV) monotherapy was investigated in 25 patients with advanced Alzheimer's disease (AD) and new-onset epileptic seizures in a prospective open-label study. At a daily dose of 1000–1500 mg, 72% were seizure-free for at least one year; 16% discontinued for untolerability; 8% were unresponsive; 4% were lost to follow-up. These results suggest the need for controlled studies to confirm if LEV can be a first-choice drug in AD. 相似文献