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981.
Autofluorescence bronchoscopy (AFB) shows good sensitivity in detecting dysplasia and bronchopulmonary cancer. However, the poor specificity of AFB would lead to excessive biopsy. The aim of the study is to establish a more effective quantitative method (optimal identification index and reference value) for characterizing the AFB images within the region of interest and discuss AFB's significance in the diagnosis of central‐type lung cancer. A total of 218 suspected lung cancer patients were enrolled in this study. A quantitative analysis based on color space (red, green, blue[RGB] and HSV system) was conducted and the result was compared with the final diagnosis obtained by the pathology of biopsy. Cases were divided into different groups according to the pathological diagnosis of normal bronchial mucosa, inflammation, low‐grade preinvasive (LGD), high‐grade preinvasive (HGD), and invasive cancer. Quantitative analyses in multi‐color spaces for the lesions showed by AFB images were conducted by software MATLAB. Finally, there is statistical significance among the different groups in some parameter in RGB and HSV system. So, both RGB and HSV quantitative analysis of autofluorescence bronchoscopy are useful to define benign and malignant diseases, which can objectively guide the bronchoscopist in selecting sites for biopsy with good pathologic correlation. 相似文献
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Nereo Segnan Silvia Minozzi Paola Armaroli Michela Cinquini Cristina Bellisario Marien González‐Lorenzo Silvia Gianola Antonio Ponti 《International journal of cancer. Journal international du cancer》2016,139(3):554-573
The general aim of this systematic review is to mitigate breast cancer (BC) overdiagnosis and overtreatment. The specific aim is to summarize available data on the occurrence and features of indolent invasive or in situ (DCIS) BC, and precisely survival of untreated cases, prevalence of occult cancers found in autopsies, frequency of regressive BC. PubMed, Embase and Cochrane Library were systematically searched up to 3/31/2014. Eligibility criteria were: cohort studies, case‐control studies, uncontrolled case series assessing survival in women with a diagnosis of BC who did not receive treatment compared to treated women; case series of autopsies estimating the prevalence of undiagnosed BC; cohort studies, case‐control studies, uncontrolled case series, case reports assessing the occurrence of spontaneous regression of BC in women with a confirmed histology diagnosis. Untreated BC: 8 cohort studies and 12 case series (3593 BC) were included. In three controlled cohort studies (diagnoses 1978–2006), the 5‐years overall survival was 19–43%. Occult BC: 8 case series (2279 autopsies) were included. The prevalence of invasive BC undiagnosed during lifetime range was 0–1.5%, while for DCIS the range was 0.2–14.7%. Spontaneous regression: 2 cohort studies, 3 case reports, 1 case series included. In the cohort studies the relative risk of regression for screen detected compared with nonscreened BC was estimated as 1.2 and 1.1. It seems plausible that around 10% of invasive BC are not symptomatic during life, and that one fith of BC patients if untreated would be alive after 5 years. Around 1 of 10 screen‐detected BC may regress according two studies. 相似文献
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[目的]探讨肿瘤学类期刊在我国医药卫生期刊中的地位。[方法]利用《2012年版中国科技期刊引证报告（扩刊版）》收录的1026种医药卫生类期刊的18项期刊评价指标数据,对18类医药卫生期刊进行聚类分析。[结果]聚类分析结果显示,18类医药卫生期刊可以分为4类,肿瘤学类期刊处于第三方阵。根据9项被引指标和9项来源指标进行的聚类分析结果显示,18类医药卫生期刊均可以分为3类．肿瘤学类期刊的被引情况和来源情况均位居第三方阵。[结论]我国肿瘤学类期刊总体状况不是太理想,还需要各期刊继续努力。 相似文献
985.
随着现代化管理方法应用于医院,医疗设备管理成为医院后勤管理中的重要一环。如何将大卫生的理念和管理方法应用于医疗设备的管理,如何在管理中提高工作效率与加强全程的质量控制值得思考。全文对现阶段医院设备管理状况进行分析,针对主要环节进行管理方法应用与改进,以完善医疗设备管理,提高工作效率。 相似文献
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Kitamura T 《Psychiatry and clinical neurosciences》2005,59(6):627-633
Informed consent has become a central part of medical decision-making. It is based on disclosure of medical information to support patients' rights for autonomous decision-making from a legal point of view. However, information disclosure may also benefit patients. Research indicates that information disclosure reduces stress among patients and that the more patients desire relevant information, the more stress-reductive information disclosure may be. In psychiatry, too, studies have shown that educating psychiatric patients may not necessarily reduce compliance or increase relapse rate. These findings are in line with patients' desires and their legal right to know their own medical matters. It has long been believed that patients, be they psychiatric or non-psychiatric, should be protected and not given information that would potentially cause distress or harm to them. However, patient's competency may be a function of the physicians' efforts to make patients understand necessary information. Therefore, a patient's right to give informed consent leads to a physician's duty to disclose individually tailored information understandable to patients. 相似文献