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61.
本文通过西宁地区113例住院冠心病人的临床分析,认为西宁地区冠心病患病率低,患者年龄大,男性患病率高于女性,而且绝经期后的高龄女性患者患病率仍然远比男性低,这些与低海拔地区不同。而冠心病各型的分布、临床症状、病死率等与低海拔地区相似。 相似文献
62.
Changes in muscle morphology in dialysis patients after 6 months of aerobic exercise training. 总被引:2,自引:1,他引:1
Giorgos K Sakkas Anthony J Sargeant Thomas H Mercer Derek Ball Pelagia Koufaki Christina Karatzaferi Patrick F Naish 《Nephrology, dialysis, transplantation》2003,18(9):1854-1861
BACKGROUND: In the present study we investigated the effect of a 6-month aerobic exercise programme on the morphology of the gastrocnemius muscle of end-stage renal disease (ESRD) patients. METHODS: Twenty-four ESRD patients volunteered to participate in the training programme and underwent muscle biopsy before training. Eighteen patients completed the training programme of whom nine agreed to a post-training biopsy (one woman and eight men, mean age 56 +/- 15 years). Data are presented for the nine subjects who were biopsied before (PRE) and after training (POST) and separately for the 15 subjects for whom we only have a biopsy before training (cross-sectional group). RESULTS: There were no significant differences (P > 0.05) in fibre type distribution or myosin heavy chain (MyHC) expression between the cross-sectional and PRE/POST groups. The mean cross-section fibre area after training (POST) increased by 46% compared with the PRE training status (P < 0.01). The proportion of atrophic fibres decreased significantly after training in type I, IIa and IIx fibre populations (from 51 to 15%, 58 to 21% and 62 to 32%, respectively). Significant differences were also found in capillary contact per fibre (CC/F), with the muscle having 24% (P < 0.05) more CC/F compared with the PRE training status. No significant differences in cytochrome c oxidase concentration were found between the groups. CONCLUSIONS: In conclusion, exercise appeared to be beneficial in renal rehabilitation by correcting the fibre atrophy, increasing the cross-section fibre area and improving the capillarization in the skeletal muscle of renal failure patients. 相似文献
63.
本文对SOD的紫外分光光度法测定进行了实用性研究。结果表明,本文方法具有用血量少,重现性好,快速、灵敏,试剂廉价等优点。西宁地区与平原地区人群的比较测定显示,前者SOD活性明显高于后者(P<0.01)。 相似文献
64.
65.
本实验以铁骨晶(多肽钙),进口脱脂奶粉,活性钙冲剂,贝壳钙为钙源添加于大鼠正常饲料中。观察结果表明:上述4组钙的吸收率分别为64.4%,69.1%,59.9%,51.6%;钙的储留率分别为89.8%,93.3%,85.2%,79.0%;钙的存留率分别为43.6%,49.0%,32.4%,26.8%;股骨指数分别为7.02×10(-3),6.43×10(-3),6.84×10(-3)。6.88×10(-3);折断力(牛顿)分别为60.54±12.55,46.81±9.32,43.26±16.62,38.24±10.79。同时以铁骨晶为钙源对70例(5~6岁)儿童进行了血清Ca,Fe,Zn,Hb及生长发育的检测。铁骨晶组的身高,体重,胸围分别比对照组增加。铁骨晶组血清Ca,Fe,Zn,Hb也均有较好的改善。这表明铁骨晶具有较好的促进钙吸收利用作用,同时能增加骨强度作用。 相似文献
66.
Bone mineral density in patients with prostatic cancer treated with orchidectomy and with estrogens 总被引:7,自引:0,他引:7
Bone mineral density (BMD) and bone mineral content (BMC) were measured in the femoral neck area, trochanteric area and Wards triangle, and in the distal radius of the left forearm before and after 1 year of endocrine treatment in 27 patients with prostatic cancer. Eleven of the patients were treated with orchidectomy and 16 with combined oral and intramuscular estrogens. The patients were free from metastases during the entire observation period. In the orchidectomized patients, BMD and BMC of the distal radius decreased significantly following treatment, whereas no changes were observed in the estrogen-treated patients. These preliminary results demonstrate that estrogens may protect bone in male subjects also and may merit further investigations on larger groups of patients. 相似文献
67.
M. S. Levine A. M. Adinolfi R. S. Fisher C. D. Hull D. Guthrie N. A. Buchwald 《Brain research》1988,440(2):267-279
These studies provide information on the changes in the ultrastructure in the caudate nucleus of aged cats. The major findings was that there was a decrease in the density of synapses in caudate neuropil. This decrease occurred in animals after 3 years of age and remained relatively constant in older animals. In conjunction with this change a population of unusually long synapses also occurred. These larger synaptic appositions were associated with enlarged spine heads. The caudate also showed a number of qualitative ultrastructural alterations. Many neurons contained accumulations of lipofuscin or lipopigment granules in aged animals. These inclusions occurred in both soma and dendrites of neurons and all types of glial cells. A unique configuration of collapsed agranular cisterns also was observed in aged animals. The present results indicate that decreases in synaptic density may by one morphological event underlying functional alterations observed in caudate neurons in aged cats. 相似文献
68.
观察18例32眼下蹲运动与高眼压的关系,分为下蹲120次,100次及80次三且,每组分别观察10眼、11眼及11眼,结果各组运动后眼压均见下降,平均为1.027±0.486kPa,1.355±0.770kPa及1.325±0.422kPa,运动前后有非常显著性差异,但各组之间差异不显著。同时观察3小时内眼压动态变化,下蹲120次组眼压下降维持时间最长,在运动后3小时与运动前眼压比较及与其余两组第3 相似文献
69.
Agents for prevention or treatment of osteoporosis must now be tested in a large animal species that exhibits bone remodeling.
Ovariectomized, nonhuman primates provide one such model, and they consistently develop osteopenia accompanied by high bone
turnover rates. The goal of this study was to further characterize this model, and particularly to determine the effect of
ovariectomy on bone strength in vertebrae and femoral necks. Longitudinal evaluations of spinal bone mass and serum markers
of bone turnover were performed in 19 sham-ovariectomized (SHAM) and 18 ovariectomized (OVX), domestically reared cynomolgus
monkeys, aged >9 years. OVX monkeys lost bone relative to both baseline values and SHAM controls. Serum markers of bone turnover
were increased by OVX. After 72 weeks, both vertebral bone compressive strength and femoral neck breaking strength were significantly
decreased in OVX animals compared with SHAM. Ovariectomized cynomolgus monkeys, like postmenopausal women, develop accelerated
bone loss, increased bone turnover, and reduced bone strength, and provide a suitable large animal model for efficacy studies
with agents for prevention or treatment of osteoporosis.
Received: 24 June 1996 / Accepted: 3 September 1996 相似文献
70.
The use of a triple lumen central venous catheter, which can be shielded from laser irradiation by metal tape, as a conduit for high frequency jet ventilation in six children, is described. The problems of anaesthesia for laryngeal laser surgery and the advantages of the technique described in this paper are discussed. 相似文献