全文获取类型
收费全文 | 31536篇 |
免费 | 2600篇 |
国内免费 | 764篇 |
专业分类
耳鼻咽喉 | 228篇 |
儿科学 | 328篇 |
妇产科学 | 314篇 |
基础医学 | 1065篇 |
口腔科学 | 395篇 |
临床医学 | 2993篇 |
内科学 | 3652篇 |
皮肤病学 | 178篇 |
神经病学 | 1404篇 |
特种医学 | 389篇 |
外国民族医学 | 2篇 |
外科学 | 1691篇 |
综合类 | 4874篇 |
现状与发展 | 1篇 |
一般理论 | 4篇 |
预防医学 | 3672篇 |
眼科学 | 535篇 |
药学 | 10280篇 |
72篇 | |
中国医学 | 1921篇 |
肿瘤学 | 902篇 |
出版年
2024年 | 72篇 |
2023年 | 544篇 |
2022年 | 730篇 |
2021年 | 1271篇 |
2020年 | 1323篇 |
2019年 | 1341篇 |
2018年 | 1234篇 |
2017年 | 1451篇 |
2016年 | 1264篇 |
2015年 | 1176篇 |
2014年 | 2416篇 |
2013年 | 3913篇 |
2012年 | 2228篇 |
2011年 | 2154篇 |
2010年 | 1774篇 |
2009年 | 1423篇 |
2008年 | 1334篇 |
2007年 | 1297篇 |
2006年 | 1190篇 |
2005年 | 1074篇 |
2004年 | 806篇 |
2003年 | 681篇 |
2002年 | 565篇 |
2001年 | 583篇 |
2000年 | 433篇 |
1999年 | 395篇 |
1998年 | 293篇 |
1997年 | 272篇 |
1996年 | 212篇 |
1995年 | 174篇 |
1994年 | 148篇 |
1993年 | 164篇 |
1992年 | 172篇 |
1991年 | 172篇 |
1990年 | 115篇 |
1989年 | 76篇 |
1988年 | 64篇 |
1987年 | 51篇 |
1986年 | 55篇 |
1985年 | 73篇 |
1984年 | 31篇 |
1983年 | 36篇 |
1982年 | 26篇 |
1981年 | 18篇 |
1980年 | 28篇 |
1979年 | 11篇 |
1978年 | 11篇 |
1977年 | 4篇 |
1976年 | 10篇 |
1974年 | 7篇 |
排序方式: 共有10000条查询结果,搜索用时 250 毫秒
41.
42.
Lonnie Embleton Juddy Wachira Allan Kamanda Violet Naanyu David Ayuku 《Culture, health & sexuality》2016,18(3):337-348
Street-connected youth in Kenya are a population potentially at risk of HIV transmission, yet little is known about their perceptions and experiences of sexually transmitted infections (STIs), despite their living in an HIV endemic region. We sought to elucidate the language and sociocultural factors rooted in street life that impact on street-connected young people’s knowledge of and perceptions about the prevention and transmission of STIs, and their diagnosis and treatment, using qualitative methods in western Kenya. We conducted a total of 25 in-depth interviews and 5 focus-group discussions with 65 participants aged 11–24 years in Eldoret, Kenya. Thematic analysis was conducted and data were coded according to themes and patterns emergent until saturation was reached. In general, street-connected young people knew of STIs and some of the common symptoms associated with these infections. However, there were many misconceptions regarding transmission and prevention. Gender inequities were prominent, as the majority of men described women as individuals who spread STIs due to unhygienic practices, urination and multiple partners. Due to misconceptions, gender inequity and lack of access to youth-friendly healthcare there is an urgent need for community-based organisations and healthcare facilities to introduce or augment their adolescent sexual and reproductive health programmes for vulnerable young people. 相似文献
43.
Interaction effects between the 5‐hydroxy tryptamine transporter‐linked polymorphic region (5‐HTTLPR) genotype and family conflict on adolescent alcohol use and misuse 下载免费PDF全文
44.
Joshua Manghelli Lisa Brown Hany B. Tadros Nabil A. Munfakh 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2015,42(5):491-494
The inflammatory response induced by cardiopulmonary bypass decreases vascular tone, which in turn can lead to vasoplegic syndrome. Indeed the hypotension consequent to on-pump cardiac surgery often necessitates vasopressor and intravenous fluid support. Methylene blue counteracts vasoplegic syndrome by inhibiting the formation of nitric oxide.We report the use of methylene blue in a 75-year-old man who developed vasoplegic syndrome after cardiac surgery. After the administration of methylene blue, his hypotension improved to the extent that he could be weaned from vasopressors. The use of methylene blue should be considered in patients who develop hypotension refractory to standard treatment after cardiac surgery. 相似文献
45.
《The Journal for Nurse Practitioners》2020,16(1):69-73
Adolescent substance use is a national public health crisis. The most commonly used substances among adolescents are nicotine, alcohol, and marijuana. Use of these substances during adolescence has serious adverse effects on brain development, with impairments that can endure into adulthood. Advanced practice nurses in primary care can address substance use in the adolescent population with the use of evidence-based interventions, such as Screening, Brief Intervention, and Referral to Treatment (SBIRT). This article describes trends in adolescent substance use and use of the SBIRT intervention for low, medium, and high-risk use in this population. 相似文献
46.
《American journal of infection control》2022,50(6):618-623
BackgroundDuring COVID-19 pandemic, a shortage of surgical masks (Mask) and respirators (Resp) was experienced worldwide. We aimed to assess its pattern of use, adverse effects and user errors by Portuguese health care professionals (HCP).MethodsA cross-sectional study was conducted through snowball convenience sample, collected by email/ social media to health care organizations. Participants answered an online anonymous survey in March 2021.ResultsMean age of 3052 respondents was 42.1 years old, 83.6% were female and 77.8% provided direct health care to COVID-19 patients. Mean time of use per shift was 6-8 hours in 40.8% of the participants. 28.0% reported never changing it during their shift. Resp use (vs Mask) was more associated with discomfort (58.2% vs 26.8%), affecting task performance (41.5 vs 18.9%) and communication (55.0 vs 40.9%), dyspnea (36.0 vs 14.4%), skin rash (37.5 vs 19.4%) and headache (37.5 vs 19.4%). Frequent user errors included touching the front while in use (70.1% Mask vs 66.3% Resp) and omitting hand hygiene before (61.8% Mask vs 55.0% Resp) or after use (61.3% Mask vs 57.0% Resp). Average number of errors was higher for Mask (4.3), than for Resp (3.2) (all: P < .001).ConclusionsMost HCP admitted an extended use of Mask/ Resp. Resp were more prone to adverse effects and Mask more prone to errors. Strategies to reinforce good practices should be considered. 相似文献
47.
余春姣 《中国继续医学教育》2020,(6):196-198
目的研究地中海贫血孕妇实施产科综合护理模式的护理配合措施及效果。方法选择78例于我院检查地中海贫血孕妇,纳入时间为2017年5月-2018年5月,采用随机数字表法将其分为综合护理组与对照组,每组均39例。其中对照组采用常规护理形式,综合护理组行产科综合护理模式,对比综合护理组与对照组护理前后心理状态评估指标及家属的护理满意度。结果护理前综合护理组与对照组患者心理状态评估指标差异无统计学意义(P>0.05),与对照组(76.92%)相比,护理后综合护理组焦虑指标、抑郁指标更低,综合护理组孕妇及家属的护理满意度(94.87%)较高(P<0.05)。结论通过综合护理模式可提升地中海贫血孕妇护理满意度,并改善其心理状态。 相似文献
48.
49.
Fiene Marie Kuijper Uma V. Mahajan Seul Ku Daniel A.N. Barbosa Sheila M. Alessi Sherman C. Stein Kyle M. Kampman Brandon S. Bentzley Casey H. Halpern 《Neuromodulation》2022,25(2):253-262
ObjectivesCocaine is the second most frequently used illicit drug worldwide (after cannabis), and cocaine use disorder (CUD)-related deaths increased globally by 80% from 1990 to 2013. There is yet to be a regulatory-approved treatment. Emerging preclinical evidence indicates that deep brain stimulation (DBS) of the nucleus accumbens may be a therapeutic option. Prior to expanding the costly investigation of DBS for treatment of CUD, it is important to ensure societal cost-effectiveness.AimsWe conducted a threshold and cost-effectiveness analysis to determine the success rate at which DBS would be equivalent to contingency management (CM), recently identified as the most efficacious therapy for treatments of CUDs.Materials and MethodsQuality of life, efficacy, and safety parameters for CM were obtained from previous literature. Costs were calculated from a societal perspective. Our model predicted the utility benefit based on quality-adjusted life-years (QALYs) and incremental-cost-effectiveness ratio resulting from two treatments on a one-, two-, and five-year timeline.ResultsOn a one-year timeline, DBS would need to impart a success rate (ie, cocaine free) of 70% for it to yield the same utility benefit (0.492 QALYs per year) as CM. At no success rate would DBS be more cost-effective (incremental-cost-effectiveness ratio <$50,000) than CM during the first year. Nevertheless, as DBS costs are front loaded, DBS would need to achieve success rates of 74% and 51% for its cost-effectiveness to exceed that of CM over a two- and five-year period, respectively.ConclusionsWe find DBS would not be cost-effective in the short term (one year) but may be cost-effective in longer timelines. Since DBS holds promise to potentially be a cost-effective treatment for CUDs, future randomized controlled trials should be performed to assess its efficacy. 相似文献
50.