全文获取类型
收费全文 | 3133篇 |
免费 | 227篇 |
国内免费 | 58篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 28篇 |
妇产科学 | 16篇 |
基础医学 | 268篇 |
口腔科学 | 72篇 |
临床医学 | 451篇 |
内科学 | 289篇 |
皮肤病学 | 37篇 |
神经病学 | 241篇 |
特种医学 | 102篇 |
外科学 | 175篇 |
综合类 | 388篇 |
预防医学 | 548篇 |
眼科学 | 45篇 |
药学 | 434篇 |
12篇 | |
中国医学 | 151篇 |
肿瘤学 | 145篇 |
出版年
2024年 | 6篇 |
2023年 | 53篇 |
2022年 | 95篇 |
2021年 | 104篇 |
2020年 | 113篇 |
2019年 | 110篇 |
2018年 | 98篇 |
2017年 | 120篇 |
2016年 | 113篇 |
2015年 | 135篇 |
2014年 | 242篇 |
2013年 | 297篇 |
2012年 | 196篇 |
2011年 | 198篇 |
2010年 | 152篇 |
2009年 | 149篇 |
2008年 | 147篇 |
2007年 | 151篇 |
2006年 | 136篇 |
2005年 | 111篇 |
2004年 | 92篇 |
2003年 | 63篇 |
2002年 | 64篇 |
2001年 | 58篇 |
2000年 | 39篇 |
1999年 | 31篇 |
1998年 | 29篇 |
1997年 | 34篇 |
1996年 | 27篇 |
1995年 | 26篇 |
1994年 | 27篇 |
1993年 | 20篇 |
1992年 | 14篇 |
1991年 | 13篇 |
1990年 | 11篇 |
1989年 | 16篇 |
1988年 | 16篇 |
1987年 | 11篇 |
1986年 | 10篇 |
1985年 | 18篇 |
1984年 | 27篇 |
1983年 | 3篇 |
1982年 | 5篇 |
1981年 | 6篇 |
1980年 | 11篇 |
1978年 | 5篇 |
1975年 | 4篇 |
1974年 | 4篇 |
1972年 | 2篇 |
1968年 | 2篇 |
排序方式: 共有3418条查询结果,搜索用时 46 毫秒
101.
102.
目的 对国外药典收载的孟鲁司特钠咀嚼片的各种有关物质方法进行比较考证,通过优化建立专属性更好的HPLC方法.方法 采用反相HPLC法,色谱柱为苯基柱(4.6mm×50mm,1.8μm),梯度洗脱,流动相A为20mmol·L-1 Na2HPO4水溶液(用磷酸调pH至5.7),流动相B为乙腈;流速为1.2m·min-1;检测波长为238nm;柱温为30℃.结果 孟鲁司特钠咀嚼片的各个杂质在此色谱条件下能得到有效分离.结论该方法可用于孟鲁司特钠咀嚼片的有关物质检查与质量控制. 相似文献
103.
104.
Jeroen P. Jansen Thomas Trikalinos Joseph C. Cappelleri Jessica Daw Sherry Andes Randa Eldessouki Georgia Salanti 《Value in health》2014,17(2):157-173
Despite the great realized or potential value of network meta-analysis of randomized controlled trial evidence to inform health care decision making, many decision makers might not be familiar with these techniques. The Task Force developed a consensus-based 26-item questionnaire to help decision makers assess the relevance and credibility of indirect treatment comparisons and network meta-analysis to help inform health care decision making. The relevance domain of the questionnaire (4 questions) calls for assessments about the applicability of network meta-analysis results to the setting of interest to the decision maker. The remaining 22 questions belong to an overall credibility domain and pertain to assessments about whether the network meta-analysis results provide a valid answer to the question they are designed to answer by examining 1) the used evidence base, 2) analysis methods, 3) reporting quality and transparency, 4) interpretation of findings, and 5) conflicts of interest. The questionnaire aims to help readers of network meta-analysis opine about their confidence in the credibility and applicability of the results of a network meta-analysis, and help make decision makers aware of the subtleties involved in the analysis of networks of randomized trial evidence. It is anticipated that user feedback will permit periodic evaluation and modification of the questionnaire. 相似文献
105.
The differentiation of clinically important Corynebacterium diphtheriae into specific biovars is complex and phylogenetically unclear. Comparative genomic analyses of 17 strains indicate that the division of C. diphtheriae into different biovars does not correlate with the variation in the gene content in the relevant metabolic categories that are potentially involved in the biovar discrimination. The biochemical separation is also not supported by phylogenetic analyses, suggesting molecular methods of typing C. diphtheriae strains should be adopted much more widely. 相似文献
106.
通过分析世界上几个公立医院占比重较高的发达国家公立医院组织结构及其改革经验,对我国公立医院组织变革进行研究,总结目前公立医院存在的问题,提出未来公立医院组织变革的方向及政策建议。 相似文献
107.
目的 对比分析不同方法治疗骨质疏松性脊柱骨折的临床效果,期许为该病的临床研究做出贡献.方法 将我院在2012年3月-2013年4月收治的30例骨质疏松性脊柱骨折患者作为研究对象,并将其随机分为观察组和对照组,每组各15例患者,观察组采用椎体后凸成形术治疗,对照组采用保守治疗,并对比分析两组患者的临床治疗效果.结果 观察组的临床治疗效果明显优于对照组,且差异具有统计学意义(P<0.05).结论 椎体后凸成形术治疗骨质疏松性脊柱骨折的临床效果十分显著,且创伤小、并发症少,利于骨质疏松性脊柱骨折患者的康复,值得推广应用. 相似文献
108.
Interest has been expressed in using a joint test procedure that requires that the results of both a trend test and a pairwise comparison test between the control and the high groups be statistically significant simultaneously at the levels of significance recommended in the FDA 2001 draft guidance for industry document for the separate tests in order for the drug effect on the development of an individual tumor type to be considered as statistically significant. Results of our simulation studies show that there is a serious consequence of large inflations of the false negative rate through large decreases of false positive rate in the use of the above joint test procedure in the final interpretation of the carcinogenicity potential of a new drug if the levels of significance recommended for separate tests are used. The inflation can be as high as 204.5% of the false negative rate when the trend test alone is required to test if the effect is statistically significant. To correct the problem, new sets of levels of significance have also been developed for those who want to use the joint test in reviews of carcinogenicity studies. 相似文献
109.
目的 观察比较江苏无锡和新疆阿合奇地区健康人群血清中胃蛋白酶原(PG)含量的差异和分布情况.方法 选择江苏无锡居住健康体检正常者768例和新疆阿合奇县居住健康体检正常者792例,采用时间分辨荧光免疫法对两个地区健康人群血清中PG Ⅰ和PGⅡ进行测定,并计算PG Ⅰ/Ⅱ值.比较两地区不同性别、年龄(按≤20岁、21 ~30岁、31 ~40岁、41~50岁、51 ~60岁、>60岁分组)、民族人群血清PG含量.结果 江苏无锡、新疆阿合奇地区血清中PG Ⅰ、PGⅡ和PG Ⅰ/Ⅱ值比较P均<0.01.两地区健康人群PG Ⅰ和PG Ⅰ/Ⅱ与性别均有关(P<0.05或<0.01),PGⅡ与性别均无关(P均>0.05);两地区男性血清中的PG Ⅰ、PGⅡ和PG Ⅰ/Ⅱ值比较P均<0.01,女性血清中PGⅡ和PGⅠ/Ⅱ值比较P均<0.01.无锡地区血清中PGⅠ、PGⅡ和PGⅠ/Ⅱ值均与年龄有关(P均<0.01),随年龄的增大呈上升趋势;阿合奇地区血清中各PG值与年龄均不相关.无锡、阿合奇地区21~30岁人群PGⅡ和PG Ⅰ/Ⅱ值比较P均<0.01;31~40岁人群PG Ⅰ和PG Ⅰ/Ⅱ值比较P均<0.01;41 ~50岁人群PGⅡ和PGⅠ/Ⅱ值比较P均<0.01;>60岁人群PG Ⅰ和PGⅠ/Ⅱ值比较P均<0.01.阿合奇地区汉族、柯尔克孜族人群血清中的PGⅠ、PGⅡ和PGⅠ/Ⅱ值比较P均>0.05,但阿合奇地区汉族和无锡地区汉族人群血清中PGⅡ和PGⅠ/Ⅱ值比较P均<0.01.结论 江苏无锡、新疆阿合奇地区健康人群血清PG水平存在差异,且在性别分布上是一致的,在年龄分布上不一致. 相似文献
110.
Huapeng Wang 《The Australian journal of forensic sciences》2020,52(5):553-568
ABSTRACT Compared with humans, who have more powerful auditory ability in discriminating and identifying speakers in noisy environments, traditional forensic automatic speaker recognizers do not perform well when dealing with noisy recordings. This paper proposes a GMM-UBM Forensic Automatic Speaker Recognition (FASR) System to reduce the effect of noise on performance. The system uses Gammatone Frequency Cepstral Coefficients (GFCC) based on an auditory periphery model and also incorporates a Principal Component Analysis (PCA) algorithm. The system was tested and validated using Mandarin voice databases compromised with different levels of white noise and office noise. The performance of the system was compared with a baseline system using Mel Frequency Cepstral Coefficients (MFCC) and also PCA under the same conditions. The results show that the performance of the combined GFCC system achieved a substantial improvement when compared with the baseline MFCC system under conditions of a high level of office noise. 相似文献