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101.
目的探讨微创治疗高血压脑出血的临床效果。方法根据CT定位,使用YL-1型颅内血肿粉碎仪对颅内血肿碎吸引流。结果治疗36例,存活出院34例,死亡2例。结论微创治疗高血压脑出血,操作简便、安全,疗效好,费用低,是对高血压脑出血治疗的有效的治疗方法。 相似文献
102.
阿片肽及其受体系统在缺血性脑损伤的病理生理发展过程中具有非常重要的作用。其在缺血性脑损伤中的作用尚存争议,本文综述了阿片肽及其受体系统在缺血性脑损伤中的作用及其可能机制,有助于探索阿片肽在围术期的合理应用,为缺血性脑损伤防治研究提供新方向。 相似文献
103.
目的尝试用小剂量尿激酶治疗老年高龄急性心肌梗死,旨在使老年高龄患者亦从溶栓治疗中获益.方法采用WHO关于急性心肌梗死(AMI)的诊断标准,收治老年高龄患者65例.随机分为两组,溶栓组31例,给予小剂量尿激酶(50×104U)30min 静脉滴入;并与非溶栓组34例对照观察.结果溶栓组冠脉再通率、五周病死率、休克、心衰分别为54.8%、6.4%、3.2%、9.7%;而对照组分别为14.7%、23.5%、26.5%:41.2%,有明显差异(P<0.01).结论有条件的基层医院依然有可能实施小剂量尿激酶对老年高龄患者的溶栓治疗,且可挽救更多老年高龄患者的生命. 相似文献
104.
目的:分析肺心病合并脑梗死的临床特点.方法:对39例肺心病合并脑梗死患者的临床资料进行回顾性分析.结果:肺心病合并脑梗死发病率6.2%,48小时内确诊率48.7%.结论:肺心病合并脑梗死临床表现不典型,及时确诊困难. 相似文献
105.
106.
目的探讨社区干预治疗对促进脑梗死患者功能恢复的效果。方法以自愿的方式选择通州区经委社区卫生服务站和八里桥社区卫生服务站所管辖社区内38例脑梗死恢复期患者随机分为治疗组和对照组,对治疗组患者进行为期1年的社区干预治疗,比较治疗组与对照组患者功能恢复情况(日常生活活动能力)。结果通过1年的早期社区干预治疗,治疗组较对照组患者功能恢复效果明显提高(P<0.01)。结论早期社区干预治疗对脑梗死患者功能恢复有促进作用。 相似文献
107.
R. Marfella F. Cacciapuoti M. Siniscalchi F. C. Sasso F. Marchese F. Cinone E. Musacchio M. A. Marfella L. Ruggiero G. Chiorazzo D. Liberti G. Chiorazzo G. F. Nicoletti C. Saron F. D’Andrea C. Ammendola M. Verza L. Coppola 《Diabetic medicine》2006,23(9):974-981
Background Oxidative stress and increased inflammation have been reported to be increased in subjects with diabetes and to be involved in the pathogenesis of cardiovascular complications after myocardial infarction (MI). It is well recognized that red wine has antioxidant and anti‐inflammatory activities. We examined the effects of moderate red wine intake on echocardiographic parameters of functional cardiac outcome in addition to inflammatory cytokines and nitrotyrosine (oxidative stress marker), in subjects with diabetes after a first uncomplicated MI. Methods One hundred and fifteen subjects with diabetes who had sustained a first non‐fatal MI were randomized to receive a moderate daily amount of red wine (intervention group) or not (control group). Echocardiographic parameters of ventricular dys‐synchrony, circulating levels of nitrotyrosine, tumour necrosis factor‐α (TNF‐α), interleukin‐6 (IL‐6), interleukin‐18 (IL‐18) and C‐reactive protein (CRP) were investigated at baseline and 12 months after randomization. Results After 1 year of diet intervention, concentrations of nitrotyrosine (P < 0.01), CRP (P < 0.01), TNF‐α (P < 0.01), IL‐6 (P < 0.01) and IL‐18 (P < 0.01) were increased in the control group compared with the intervention group. In addition, myocardial performance index (P < 0.02) was higher, and transmitral Doppler flow (P < 0.05), pulmonary venous flow analysis (P < 0.02) and ejection fraction (P < 0.05) were lower in the control group, indicating ventricular dys‐synchrony. The concentrations of nitrotyrosine, CRP, TNF‐α and IL‐6 were related to echocardiographic parameters of ventricular dys‐synchrony. Conclusions In subjects with diabetes, red wine consumption, taken with meals, significantly reduces oxidative stress and pro‐inflammatory cytokines as well as improving cardiac function after MI. Moderate red wine intake with meals may have a beneficial effect in the prevention of cardiovascular complications after MI in subjects with diabetes. 相似文献
108.
109.
I. Y. Shvera A. M. Cherniavsky W. Yu. Ussov M. P. Plotnikov A. A. Sokolov V. M. Shipulin V. I. Chernov 《European journal of nuclear medicine and molecular imaging》1995,22(2):132-138
In this study we aimed to work out a quantitative prognostic index for preoperative assessment of brain technetium-99m hexamethylpropylene amine oxime (HMPAO) single-photon emission tomography (SPET) in patients referred for urgent carotid endarterectomy due to acute obstructive disease of the internal carotid artery (ICA) and neurological deficit. To this end we compared data from preoperative SPET studies with the postinterventional changes in neurological status in 20 patients (17 males, three females; mean age 53 years, SD 4 years) with acute ischaemic cerebral disorders induced by obstruction of the ICA. Carotid obstruction was diagnosed by ultrasound B-mode study. All patients underwent urgent carotid endarterectomy from the ICA. Patients were divided into two groups in accordance with the results of postoperative follow-up: group A comprised patients with significant (more than 3 points) postoperative improvement in neurological condition as quantified by the Canadian Neurological Scale (11 patients); group B consisted of patients with minimal improvement or deterioration (nine, three of whom died). All patients were studied preoperatively by99mTc-HMPAO SPET. The volume of nonperfused tissue (VS, cm3) was quantified using the Mountz technique. Hypoperfused volume (V
hypoperf, cm3) in the affected hemisphere was calculated as the total volume of voxels with99mTc-HMPAO uptake <90% of the contralateral symmetric voxels. Discriminant prognostic function was calculated by discriminant analysis as:PF = 0.072×VS + 29.46×(VS/V
hypoperf). Patients with preoperativePF values <8.20 demonstrated postoperative improvement in neurological status, while the group withPF>8.90 comprised patients who demonstrated minimal improvement or deterioration. PF values in the range 8.20–8.90 carried an indefinite prognosis. We conclude that the preoperative99mTc-HMPAO SPET can be used for the selection of patients in whom improvement in neurological status may be expected after urgent surgical correction of acute extracranial obstruction of the ICA. 相似文献
110.
曾群英 《中国新药与临床杂志》1995,(6)
目的:探索地奥心血康(DAXXK)对急性心肌梗死(AMI)的疗效。方法:AMI病人89例,采用随机单盲法分为2组,DAXXK胶囊组45例,男性36例,女性9例,年龄59±s8a.采用DAXXK200mg,po,tid,共4wk。地尔硫组44例,男性34例,女性10例,年龄58±7a.采用盐酸地尔硫30mg,po,tid,共4wk。结果:DAXXK组治疗后心绞痛发作频率须静脉滴注硝酸甘油的量及镇痛药需用次数均显著低于对照组;心功能(SV,CO,LVEF,STI)改善亦显著优于对照组;心肌酶(GOT,CK,CK-MB,LDH)峰值,住院期间心力衰竭及心律失常发生率亦均显著低于对照组。结论:DAXXK是防治AMI有较好疗效的纯中药制剂。 相似文献