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S. Akash Prabhu Aruna K. Kunhiraman T.B. Naveen R. Ajay Rakkesh Marloes Peeters 《Sustainable Chemistry and Pharmacy》2022
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104.
碳纳米管(CNT)是一种具有特殊结构和性质的新型一维纳米材料。CNT具有优异的力学性能,良好的导热性能和极好的场致电子发射效应等优点,引起各国研究者的广泛关注。近年来,CNT在口腔医学领域的使用也逐渐增多,显示出良好的应用前景。本文就CNT的主要性能及其在口腔领域中应用作一综述。 相似文献
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Krzysztof Szwed Wojciech Pawliszak Magdalena Szwed Marta Tomaszewska Lech Anisimowicz Alina Borkowska 《The Journal of thoracic and cardiovascular surgery》2021,161(4):1275-1282.e4
BackgroundNeuropsychiatric complications of surgical coronary revascularization are inconspicuous but frequent and clinically relevant. So far, attempts to reduce their occurrence, such as the introduction of off-pump coronary artery bypass (OPCAB) grafting method, have not brought the desired results. The aim of this trial was to determine whether using any of the 2 selected modifications of OPCAB could decrease the incidence of these undesired sequelae.MethodsIn this single-center, assessor- and patient-blinded, superiority, randomized controlled trial, 192 patients scheduled for elective isolated OPCAB were randomized to 3 parallel arms. The control arm underwent “conventional” OPCAB with vein grafts. The first study arm underwent anaortic OPCAB (ANA) with total arterial revascularization. The second study arm underwent OPCAB with vein grafts using carbon dioxide surgical field flooding (CO2FF). Outcomes included the incidence of postoperative delirium (PD) and early postoperative cognitive dysfunction (ePOCD).ResultsThe incidence of PD was 35.9% in the control (OPCAB) arm, 32.8% in the CO2FF arm, and 12.5% in the ANA arm (χ2 [2, N = 191] = 10.17; P = .006). Post hoc tests revealed that the incidence of PD in the ANA arm differed from that in the OPCAB arm (odds ratio [OR], 0.26; 95% confidence interval [CI], 0.09-0.68; P = .002). The incidence of ePOCD was 34.4% in the OPCAB arm, 28.1% in the CO2FF arm, and 9.5% in the ANA arm (χ2 [2, N = 191] = 11.58; P = .003). Post hoc tests revealed that the incidence of ePOCD differed between the ANA and OPCAB arms (OR, 0.20; 95% CI, 0.06-0.58; P < .001).ConclusionsPerforming ANA significantly decreases the incidence of PD and ePOCD compared with “conventional” OPCAB with vein grafts, whereas CO2FF is inconsequential in this regard. These results, which probably reflect decreased delivery of embolic load to the brain in ANA, may have practical applicability in daily practice to improve clinical outcomes. 相似文献
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Ryouhei Yoshihara Shigeki Nozawa Yoshihiro Hase Issay Narumi Jun Hidema Ayako N. Sakamoto 《Journal of radiation research》2013,54(6):1050-1056
To assess the mutational effects of radiation on vigorously proliferating plant tissue, the mutation spectrum was analyzed with Arabidopsis seedlings using the plasmid-rescue method. Transgenic plants containing the Escherichia coli rpsL gene were irradiated with γ-rays and carbon ion beams (320-MeV 12C6+), and mutations in the rpsL gene were analyzed. Mutant frequency increased significantly following irradiation by γ-rays, but not by 320-MeV 12C6+. Mutation spectra showed that both radiations increased the frequency of frameshifts and other mutations, including deletions and insertions, but only γ-rays increased the frequency of total base substitutions. These results suggest that the type of DNA lesions which cause base substitutions were less often induced by 320-MeV 12C6+ than by γ-rays in Arabidopsis seedlings. Furthermore, γ-rays never increased the frequencies of G:C to T:A or A:T to C:G transversions, which are caused by oxidized guanine; 320-MeV 12C6+, however, produced a slight increase in both transversions. Instead, γ-rays produced a significant increase in the frequency of G:C to A:T transitions. These results suggest that 8-oxoguanine has little effect on mutagenesis in Arabidopsis cells. 相似文献
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AbstractAntihepatotoxic activity of a resuspended residue of the alcohol extract of Amoora rohituka W & A. (Meliaceae) was studied in rats with hepatic injury induced by carbon tetrachloride. Carbon tetrachloride (1 ml/kg, i.p.) was administered twice a week for 3 weeks and an extract of A. rohituka (50 mg/kg/day) was given orally for the same period. The rats were sacrificed 24 h after the last CC14 challenge. Carbon tetrachloride induced elevations of alkaline phosphatase (ALP), glutamate pyruvate transaminase (CPT), alanine aminotransferase (ALAT), glutamate oxaloacetate transaminase (GOT), aspartate aminotransferase (ASAT) and lactate dehydrogenase (LDH) and total plasma bilirubin concentration as well as depression of total plasma cholesterol concentration were reduced significantly by the concurrent treatment of rats with A. rohituka suspension. Changes in the histological architecture of the liver produced by CC14 where also protected by the administration of A. rohituka suspension. These results indicate that A. rohituka suspension possesses hepatoprotective action. 相似文献
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Waterborne Polyurethane Colloids with Sensitive CO2‐Switchable Hydrophilic/Hydrophobic Properties
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A novel conceptual approach to gas‐responsive functionality, with the capability to tune the amphiphilic characteristics of existing waterborne polyurethanes (WPUs), via CO2/N2 bubbling in aqueous solution, is exploited. In this study, a series of functional WPUs are successfully prepared. These colloids exhibit high aqueous stability, excellent capability for emulsification/demulsification as a surfactant, and reversible hydrophilic/hydrophobic phase transition owing to reversible formation of carboxylic acid moieties induced by bubbling CO2 gas. More interestingly, when carboxylated multiwalled carbon nanotubes (CNTs) are covalently incorporated into these WPUs, the CNT exhibits CO2‐switchable amphiphilic behavior in a two‐phase mixture of n‐butanol (BuOH)/deionized water, forming a stable hydrophobic CNT dispersion in BuOH upon CO2 bubbling, and reversibly reverting to the previous hydrophilic CNT dispersion in water upon N2 bubbling. With simple preparation and switchable amphiphilic properties, these CO2‐responsive WPUs offer a paradigm for the development of multifunctional gas‐responsive polymers. 相似文献