Isolectin B4 binding in populations of rat trigeminal ganglion cells

We have recently classified dissociated trigeminal ganglion cells into nine types using electrophysiological current signatures. In the present study, we investigated the relationship between isolectin B₄ (IB₄) binding and the cell types in rat trigeminal ganglion cells. We found that IB₄ was bound to all type 2 cells and more than 70% of cell types 1 and 13; however, it was bound to less than 20% of cell types 7 and 8 and did not bind at all to cell types 3–5 and 9. Thus, each trigeminal ganglion cell type showed high homogeneity in IB₄ binding. These results correspond to reported IB₄ binding profiles in the matched dorsal root ganglion cell types, except for types 5 and 7.     

三叉神经痛型巨型桥小脑角区胆脂瘤的治疗体会

目的探讨三叉神经痛型巨型桥小脑角胆脂瘤的发生机制、临床表现和治疗原则。方法回顾性总结43例以三叉神经痛为主要表现的胆脂瘤患者的临床表现、肿瘤生长部位与大小、手术入路与技巧、结果和术后并发症等资料。结果肿瘤全切32例,次全切除11例。所有患者均表现为同侧三叉神经痛。术中发现30例肿瘤将三叉神经包绕在瘤内。术后三叉神经痛均消失,面部感觉减退8例,加重3例,外展神经麻痹3例;2例脑脊液漏（2005年之前）,5例疑是无菌性脑膜炎。结论桥小脑角区巨型胆脂瘤与三叉神经痛的关系复杂且导致的三叉神经痛临床表现多不很典型,应采取手术治疗,根据肿瘤部位采用不同术式,术中根据肿瘤和周围结构的关系以确定是否全切,对于三叉神经压迫明显,或是被肿瘤紧密包裹、黏连者,可同时行三叉神经感觉根部分切断术,术后注意无菌性脑膜炎脑脊液漏等并发症。     

变频电针配合改良药笔灸法治疗带状疱疹后遗神经痛

目的:观察变频电针配合改良药笔灸法治疗带状疱疹后遗神经痛的临床疗效。方法:将37例带状疱疹后遗神经痛患者随机分为对照组19例,采用口服布洛芬胶囊加维生素B1治疗,治疗组18例,采用变频电针配合改良药笔灸法治疗,比较两组视觉模拟评分(VAS)变化及临床疗效。结果:治疗组带状疱疹后遗神经痛的治疗总有效率达到94.44%(17/18),优于对照组的73.68%(14/19)(P<0.05);两组治疗后VAS评分较治疗前均有改善(P<0.05),但两组治疗后比较差异无统计学意义(P>0.05)。结论:变频电针配合改良药笔灸法能有效缓解带状疱疹后遗神经疼痛。     

下关穴不同深度针刺治疗肝阳上亢型三叉神经痛:随机对照研究

目的:观察深刺及浅刺下关穴治疗肝阳上亢型原发性三叉神经痛(PTN)的疗效差异。方法:选择肝阳上亢型原发性三叉神经痛63例,随机分为深刺组(32例)和浅刺组(31例),两组均取患侧下关,双侧合谷、太冲及与病变神经干分支相应的攒竹、四白、夹承浆穴。深刺组针刺下关至蝶腭神经节(SPG),攒竹、四白、夹承浆分别刺入眶上孔、眶下孔、颏孔;浅刺组行常规针刺,针刺后均接G6805电针仪,每次通电30min,隔日1次。治疗2个疗程后,观察患者疼痛指标、中医证候指标及临床疗效。结果:深刺组患者疼痛视觉模拟评分(VAS)、中医证候各项评分(疼痛程度、疼痛次数、心烦、目赤、口苦、胁痛)均较治疗前明显降低(均P<0.01);浅刺组除胁痛(P>0.05)以外,其余以上指标均明显降低(P<0.01,P<0.05);两组治疗后比较,深刺组VAS评分、中医证候中疼痛程度、目赤及总分减少更显著(均P<0.05)。深刺组、浅刺组疾病总有效率分别为93.8%(30/32)和87.1%(27/31),深刺组疗效优于浅刺组(P<0.05)。两组均未观察到不良反应。结论:电针治疗肝阳上亢型三叉神经痛疗效显著,深刺下关透蝶腭神经节较常规针刺下关疗效更佳。     

Lacrimal dacryostenosis with severe facial pain misdiagnosed as trigeminal neuralgia

A 47-year-old woman developed intermittent shooting pain around the right side of the nose and eyes. A neurologist initially diagnosed trigeminal neuralgia, but carbamazepine did not improve the pain. Two months later, she presented with a pus-like eye discharge and was referred to us for further examination. Poor saline irrigation from the lacrimal puncta and computed tomography findings of a swollen lacrimal sac indicated a diagnosis of lacrimal dacryostenosis. At this point, the pain and dizziness as a side effect of carbamazepine had become intolerable. Endoscopic intranasal dacryocystorhinostomy confirmed stenosis of the nasolachrymal duct and a thickened lacrimal sac. The postoperative course was uneventful, and the facial pain disappeared. This experience suggests the importance of recognizing lacrimal dacryostenosis as a differential diagnosis of facial pain around the eyes and nose. We also recommend a review of an original diagnosis of trigeminal neuralgia if carbamazepine fails to relieve facial pain.     

三叉神经痛治验一则

三叉神经痛是指发生在面部三叉神经分布区域内的剧烈疼痛,作者利用针刀和针刺治疗三叉神经痛一则,疗效显著。     

三叉神经痛治验一则

三叉神经痛是指发生在面部三叉神经分布区域内的剧烈疼痛,作者利用针刀和针刺治疗三叉神经痛一则,疗效显著。     

刺络拔罐加温针灸治疗带状疱疹后遗神经痛临床研究

目的：观察刺络拔罐加温针灸治疗带状疱疹后遗神经痛临床疗效。方法：将 52 例患者按随机数字表法分为刺络拔罐加温针灸组（治疗组）33 例,用梅花针叩刺,以痛处为叩刺部位;中药治疗组（对照组）19 例,辨证治疗,肝经郁热证：拟龙胆泻肝汤加减;脾虚湿蕴证：拟除湿胃苓汤加减;气滞血瘀证：拟柴胡疏肝散合桃红四物汤加减。结果：治疗组有效率为 100.00% ,对照组有效率为 73.68% ,两组有效率比较,差异有统计学意义（P 〈 0.05）。结论：刺络拔罐加温针灸治疗带状疱疹后遗神经痛有较好的临床疗效。