重症胆管炎23例临床治疗分析

目的：探讨急性重症胆管炎患者的手术时机和死亡原因。方法：回顾性分析23例急性重症胆管炎患者的治疗及预后情况。结果：死亡2例（手术死亡及传统治疗死亡各1例）。早期大剂量短期应用糖皮质激素患者休克得到纠正率85％，明显高于未用糖皮质激素患者休克纠正率50％。结论：急性重症胆管炎患者应在出现休克和（或）精神症状之前手术，对已出现休克的患者，应先给予充分的保守治疗，待病情稳定后再手术。贻误手术时机，严重合并症如多器官功能衰竭及高龄是死亡的主要原因。     

瘦素、C-反应蛋白与老年急性冠脉综合征患者的相关研究

目的探讨急性冠脉综合征(ACS)患者血浆瘦素(LP)及C-反应蛋白(CRP)水平的变化及其临床意义。方法测定急性心肌梗死组(AMI组)、不稳定型心绞痛组(UA组)、对照组(健康体检者)血浆LP及CRP浓度,分析LP、CRP与病情严重程度的关系以及LP与CRP的相关性。结果AMI组、UA组患者血浆LP、CRP浓度较对照组显著升高(P<0.01),2组患者血浆LP与CRP浓度之间均呈显著正相关;AMI组血浆LP、CRP浓度比UA组明显升高(P<0.05)。结论血浆LP及CRP浓度与ACS病情严重性呈正相关,且LP与CRP浓度呈正相关。说明LP与CRP共同参与组织炎症反应,是ACS重要的危险因素及预测因子。     

急性脑血管病病人应激状态的临床特点及护理

[目的 ]分析急性脑血管病(ACVD)应激状态的临床特点 ,探讨防治策略及护理对策。 [方法 ]回顾分析 3 62例ACVD病人的临床资料。[结果 ]ACVD病人应激反应的发生率为 47.5 1% ,病死率为 11.88%。 [结论 ]早期明确诊断与治疗 ,并采取措施积极调控机体应激状态 ,加强护理 ,有助于控制病情和促进康复 ,降低病死率。     

The shape of stress: the use of frequent sampling to measure temporal variation in S‐IgA levels during acute stress

Previous studies have indicated that statistically significant increases in Secretory immunoglobulin A (S‐IgA) can be achieved in as little as 5min as a result of mental stress. However, the temporal resolution of these changes is low and therefore the rate and pattern of changes during the stress task and during subsequent recovery is unclear. A within‐subjects design was used to examine levels of S‐IgA before, during and after a short (8 min) mental stress task. S‐IgA was measured from saliva samples obtained every 2 min during the entire 30‐min session. Significant increases in S‐IgA concentration were observed as early as the task instruction period, with additional increases during the stress task itself. The data also show a rapid recovery of S‐IgA, with a return to baseline levels within 6 min. Results suggest that S‐IgA changes can occur very rapidly and that the observed increases are short‐lived. Copyright © 2007 John Wiley & Sons, Ltd.     

SARS患者白细胞形态学观察

目的：观察不同病程的严重急性呼吸综合征(SARS)患者白细胞形态的变化。方法：对不同病程SARS患者的血涂片进行形态观察和分析。结果：SARS患者发病期间，其粒细胞比例明显升高，淋巴细胞明显减少，而且出现核仁及多核仁现象，随病程进展，粒细胞、淋巴细胞的比例逐渐恢复至正常范围，有核仁的淋巴细胞也随之减少至消失，均为正常成熟的淋巴细胞。结论：SARS患者发病期间，外周血涂片白细胞分类中，中性粒细胞(分叶核)比例升高，淋巴细胞比例明显减少，随病程进展出现的核仁淋巴细胞减少，血细胞比例、形态恢复正常。