全文获取类型
收费全文 | 389910篇 |
免费 | 27268篇 |
国内免费 | 14335篇 |
专业分类
耳鼻咽喉 | 4927篇 |
儿科学 | 11996篇 |
妇产科学 | 4974篇 |
基础医学 | 47660篇 |
口腔科学 | 9457篇 |
临床医学 | 39977篇 |
内科学 | 63873篇 |
皮肤病学 | 7390篇 |
神经病学 | 20657篇 |
特种医学 | 15928篇 |
外国民族医学 | 140篇 |
外科学 | 47567篇 |
综合类 | 45371篇 |
现状与发展 | 71篇 |
预防医学 | 19876篇 |
眼科学 | 7937篇 |
药学 | 36257篇 |
123篇 | |
中国医学 | 9801篇 |
肿瘤学 | 37531篇 |
出版年
2024年 | 804篇 |
2023年 | 4783篇 |
2022年 | 12269篇 |
2021年 | 16006篇 |
2020年 | 10544篇 |
2019年 | 16044篇 |
2018年 | 11116篇 |
2017年 | 10627篇 |
2016年 | 12788篇 |
2015年 | 16406篇 |
2014年 | 26967篇 |
2013年 | 26034篇 |
2012年 | 27658篇 |
2011年 | 25615篇 |
2010年 | 22781篇 |
2009年 | 22008篇 |
2008年 | 21141篇 |
2007年 | 21317篇 |
2006年 | 18608篇 |
2005年 | 14445篇 |
2004年 | 10224篇 |
2003年 | 8906篇 |
2002年 | 7280篇 |
2001年 | 6152篇 |
2000年 | 5217篇 |
1999年 | 4222篇 |
1998年 | 4510篇 |
1997年 | 4110篇 |
1996年 | 3632篇 |
1995年 | 3383篇 |
1994年 | 3096篇 |
1993年 | 2493篇 |
1992年 | 2397篇 |
1991年 | 2227篇 |
1990年 | 1988篇 |
1989年 | 1899篇 |
1988年 | 1769篇 |
1987年 | 1482篇 |
1986年 | 1291篇 |
1985年 | 2390篇 |
1984年 | 2416篇 |
1983年 | 1745篇 |
1982年 | 1854篇 |
1981年 | 1721篇 |
1980年 | 1481篇 |
1979年 | 1234篇 |
1978年 | 938篇 |
1977年 | 885篇 |
1976年 | 767篇 |
1974年 | 487篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
951.
应用流式细胞计对30例宫颈腺癌和混合癌细胞的DNA指数和细胞增殖周期各时相细胞分布比例进行分析,结果显示非整倍体肿瘤29例,占96.7%.流式细胞计在诊断恶性肿瘤方面是有价值的。细胞增殖周期比DNA指数对预后的估价更有意义.乳头型腺癌、分化I级的肿瘤,S+G2M比率最低,5年生存率最高. 相似文献
952.
Chun Yuan Jay S. Tsuruda Kirk N. Beach Cecil E. Hayes Marina S. Ferguson Charles E. Alpers Thomas K. Foo D. Eugene Strandness 《Journal of magnetic resonance imaging : JMRI》1994,4(1):43-49
Atherosclerotic cardiovascular disease is the most common cause of death in the United States. Investigation of atherosclerotic plaque morphology and composition is important because the findings may be useful in predicting prognosis or response to therapy. This study presents high-resolution magnetic resonance (MR) imaging techniques developed on a 1.5-T whole-body imager with a custom-built surface coil, for characterizing the composition and morphology of plaque removed at carotid endarterectomy. The initial comparison of MR imaging and histologic results showed good correlation. In conjunction with MR angiography, these techniques could be used in in vivo imaging to define the size, location, and contents of atherosclerotic plaque at the carotid bifurcation. 相似文献
953.
CHM. SAMAMA R. QUEZADA B. RIOU E. MOURGEON M. AROCK A. ANKRI P. VIARS 《Acta anaesthesiologica Scandinavica》1994,38(3):232-237
A prospective study was conducted to evaluate a new compact portable coagulation monitor (Ciba–Corning Biotrack 512 Monitor), which enables the clinician to perform instantaneous activated partial thromboplastin time (APTT) and prothrombin time (PT). 126 patients scheduled for heparinized and nonheparinized vascular surgery, and gynaecological surgery, were included. A drop of capillary or venous whole blood was applied in disposable cartridges to successively perform APTT and PT, and the results of the tests were compared with conventional laboratory methods, performed in two different laboratories (Lab. A and B). Comparisons between Lab. A. and Lab. B. enables determination of the bias, precision, and percent of outliers (patients whose values differed more than 20%) in conventional methods. The reference value was defined as the mean of Lab. A. and Lab. B. values. For PT, there were no statistical differences between the capillary and venous samples performed with the portable monitor, and the reference value, for the bias, the precision and the proportion of outliers. For APTT, there were no statistical differences between the capillary and venous samples performed with the portable monitor, and the reference value, for the bias and the precision. The percent of outliers, however, was significantly greater with the venous sample of the compact monitor than with the reference (48 versus 22%), and even if it did not reach the statistical significance ( P = 0.07) it was also higher with the capillary sample performed with the Ciba Monitor than with the reference (33%). In conclusion the assessment of blood coagulation using this new compact monitor could be of major interest during the intraoperative period when immediate results are mandatory, even if PT is more accurate than APTT with this new method. 相似文献
954.
骨膜间质干细胞移植时机的实验和临床研究 总被引:2,自引:2,他引:0
目的 研究骨膜间质干细胞异体移植时机。方法 根据骨缺损内纤维组织生长时间的不同,将从大鼠骨膜分离培养的细胞分别分批植入,在植入的第2、3、4和8周时动态观察其成骨量,即骨小梁体积比;另将幼儿骨膜间质干细胞悬液,移植于26例长管状骨干骨折2周后的缺损内,观察骨折临床愈合的时间。结果 大鼠骨缺损后2周以内移植干细胞其骨小梁体积比大,愈合快,2周以后与对照组比无显著差异;临床应用9个月内病人骨折缺损愈合15例(57.7%),骨不愈合者11例(42.3%)。结论 大鼠骨缺损2周以内移植干细胞其疗效好,大鼠实验和临床上骨缺损2周以后移植骨膜间质干细胞不能明显促进骨缺损愈合。 相似文献
955.
956.
作者合成了13个对-苯二甲酸衍生物,其中有9个化合物尚未见文献报道。通过对HL-60细胞诱导分化活性试验,发现有两个化合物在浓度为5×10 ̄(-6)mol/L时,可使细胞分化率达55%,低于维A酸的分化率(79%,10 ̄(-7)mol/L)。 相似文献
957.
Although extensively pursued, the central respiratory neurons have remained elusive. We departed from the more conventional physiologic and morphologic methods of system and tissue examination and cultured dissociated fetal rat cells (Fitzgerald et al., J Neurosci Res 33:579-589, 1992) from the area of the nucleus ambiguus and the nucleus tractus solitarius located within the 2 mm rostral to the obex. Pacemaker-like cells, with a regular single or bursting activity, studied at 3-5 weeks of age, responded to very small pulses of CO2 (50 ms) and low pH with an increase in spike frequency and a decrease in spike amplitude. Other irregularly beating or silent cells did not respond or else required very large pulses (> 200 ms) to do so. The pacemaker cells also responded to hypoxia induced by administration of sodium hydrosulfite with an increase in spike frequency and amplitude; high oxygen (> 600 torr) and adenosine produced a decrease in electrical activity. Most of these cells were multipolar after staining with antibodies to neuron-specific enolase (NSE) and Fragment C of tetanus toxin. They did not stain for choline acetyltransferase (ChAT). The results suggest that these cultured cells, expressing a phenotype inherently responsive to CO2 and low pH, have the characteristics of central respiratory chemoreceptors, and may be involved in the generation of the respiratory rhythm. 相似文献
958.
David M. Warshauer Richard C. Semelka Susan M. Ascher 《Journal of magnetic resonance imaging : JMRI》1994,4(4):553-557
Small nodular lesions in the liver and spleen have been reported as an infrequent manifestation of sarcoidosis. Five patients with this appearance on either dynamic contrast material—enhanced computed tomographic (CT) or ultrasound scans underwent magnetic resonance (MR) imaging with and without dynamic gadolinium enhancement. The lesions were relatively uniform in size, ranging from 0.5 to 1.5 cm. On CT scans, they were hypoattenuating relative to surrounding parenchyma. On MR images, the lesions were hypointense relative to background parenchyma with all sequences. No substantial enhancement was observed in the lesions, although lesion conspicuity decreased over time on serial postcontrast images. Lesion conspicuity was greatest on either T2-weighted fat-suppressed (T2FS) images or early-phase dynamic contrast-enhanced images. Abdominal adenopathy was seen in three of the five patients and was hyperintense relative to liver on T2FS images in two and intermediate in intensity in one patient. 相似文献
959.
The ability to measure skeletal muscle motion with phase-contrast magnetic resonance (MR) imaging was tested with a motion phantom that simulated muscle activity. Quantitative analytic data on unidimensional, bidirectional skeletal muscle motion measured in vivo was obtained in four healthy volunteers. MR images of the subjectss' forearms were obtained during flexion and extension of the fingers and of the anterior and posterior muscle compartments of the lower leg with various resistances to ankle dorsiflexion and plantar flexion. It was necessary to correct the data for the effects of eddy currents. In vitro evaluation of the technique was done by studying through-plane sinusoidal motion of solid objects. The largest error was underestimation of the peak excursion of 11.5 mm by 0.09 mm (the root mean square error for the cycle was 0.04 mm) In vivo experiments demonstrated the contraction of muscles in relation to each other. Data acquisition and analysis techniques must be refined, but measuring skeletal muscle motion with phase-contrast MR imaging should enhance the understanding of bioengineering fundamentals and muscular changes in disease and adaptation. 相似文献
960.