Effects of Forming Parameters on Fatigue Life in Incremental Sheet Punching

In order to investigate the effects of main forming parameters on the fatigue life in incremental sheet punching, wavelength and amplitude were selected as factors, and fatigue life of truncated pyramids and virgin material was selected as indicator. The effects of the parameters were identified whereby the design of full factorial experiment, fatigue comparative test, analysis of variance, Tukey test, and t-test. It was found that wavelength and amplitude significantly affect the fatigue life. In addition, the improvement of fatigue life decreased with the increment of wavelength and increased with the increment of amplitude when it is less than a certain value, followed by decreasing.     

HPLC-CAD法同时测定氨糖美辛肠溶片中两种成分的含量

目的:对于现行标准中氨糖美辛肠溶片含量测定步骤繁琐，氨基柱柱效下降快等问题，建立一种高效液相色谱-电喷雾检测器(HPLC-CAD)同时测定两种主成分的方法。方法:色谱柱：Waters XBridge-C₁₈(4.6 mm×250 mm, 5μm),流动相A为0.1%冰醋酸溶液，流动相B为乙腈，采用梯度洗脱的方式，流速为0.7 mL·min^-1,柱温：30℃,进样量：20μL,检测器为CAD(雾化温度：45℃;数据采集频率：10 Hz;滤光片：10.0 s)。结果:供试品溶液中两主峰达到基线分离，阴性溶液中辅料峰与主峰无干扰。吲哚美辛和盐酸氨基葡萄糖线性范围分别为0.0125～0.25 mg·mL^-1和0.037 5～0.75 mg·mL^-1,加样回收率分别为100.00%～102.21%、98.74%～101.90%,统计学t检验结果显示该方法与药典标准方法的测定结果无显著差异。结论:该方法具有操作简便，灵敏度高，专属性强，可作为氨糖美辛肠溶片的含量测定替代方法。     

Changing landscape in living kidney donation in Greece

Patients with end-stage renal disease in Greece are facing long waiting times to receive a kidney transplant from a deceased donor. Living kidney donation offers a valuable alternative that provides optimal outcomes and significantly expands the donor pool but still remains relatively underutilised. Developments around the world in the field of kidney transplantation mandate a change in current practice to include additional options for living donation through paired exchange, antibody-incompatible transplantation and other strategies, following careful consideration of the cultural and ethical factors involved in these complex clinical decisions. An increase in living donation rates may be achieved in several ways, including targeted campaigning to overcome potential barriers. Educating clinicians on transplantation will prove as equally important as informing patients and prospective donors but requires training and resources. Adoption of established practices and implementation of new strategies must be tailored to the needs of the Greek donor and recipient population. Local beliefs about donation, perception of associated risk and other social characteristics must be considered in the design of future strategies. Facilitating living donation in a safe environment with appropriate donor and recipient education will form the solid foundation of a new era of kidney transplantation in Greece.