Nutritional evaluation of gynecologic cancer patients during initial diagnosis of their disease

Ninety-seven gynecologic cancer patients received a thorough nutritional assessment during the initial evaluation of their disease. Patients with Stages III and IV ovarian cancer were shown to have severe protein-calorie malnutrition (p < 0.01) unrelated to any gastrointestinal obstruction or laparotomies. Patients with other types of gynecologic cancers at all stages demonstrated nearly normal nutritional assessment parameters, with the exception of recent weight loss. Nutritional assessment and active nutritional intervention therapy are suggested especially for patients with advanced ovarian cancer.     

Lack of association between contraceptive usage and congenital malformations in offspring

Previous reports have linked the use of oral contraceptives and spermicides to the occurrence of malformations in offspring. With information from 12,440 women interviewed during the delivery hospitalization we found no relationship between contraceptive method and the occurrence of malformations. Whereas any unnecessary drug should be avoided during pregnancy, prior contraceptive method seems to be unrelated to the risk of congenital malformations.     

Genital warts and cervical cancer: II. Is human papillomavirus infection the trigger to cervical carcinogenesis?

Evidence of a biologically significant association between subclinical papillomavirus infection (SPI) and cervical neoplasia raises the question of whether this is a causal relationship. Human papillomavirus (HPV) infection of metaplastic epithelium in the cervical transformation zone is relatively common, producing latent infection in susceptible persons. The epidemiological characteristics of SPI and cervical cancer are essentially identical and there is a strong clinico-pathological association between condylomas and anogenital carcinoma. Tissue culture cells have been transformed from a normal to a neoplastic phenotype by animal papillomaviruses, and there is preliminary data reporting upon the successful identification of HPV genomic sequences in tumor cells. SPI commonly coexists with foci of cervical intraepithelial neoplasia (CIN). Areas of apparent transition are seen, and these two lesions are linked by a discernible spectrum of morphologic change. Such circumstantial evidence gives biological plausibility to the suggestion that HPV may be a cervical carcinogen. It is postulated that cervical neoplasia arises by progression from benign viral hyperplasia, through varying stages of koilocytotic atypia with associated dysplasia, to unremarkable carcinoma in situ. Invasion is presumed to reflect the emergence of an aggressive heteroploid clone, an age-related decline in host immune surveillance or an interaction of both factors.     

Condoms are not a risk factor for sensitization to latex

The study was conducted to assess the prevalence of sensitization to latex in a group of women with a high risk for atopy and to determine whether the use of condoms is a relevant risk factor. In a prospective study, 100 atopic women (defined as having specific IgE to common aero- or nutritional allergens) were screened for specific IgE antibodies to latex after delivery: Ten of the 100 women (10%) showed specific IgE to latex. Total IgE concentrations were higher with a history of occupational exposure or of symptoms after contact with latex (p < 0.05, and p < 0.005, respectively), but condom users were not significantly more frequent in the latex-positive group. Our results indicate that prior use of condoms does not appear to be a specific risk factor for sensitization to latex in post-partum women at high-risk for atopy. Latex-free condoms should only be recommended to women already known to be sensitized to latex.     

产科疾病ICD-10编码质量调查分析及建议

目的通过调查我院产科疾病ICD-10编码质量,更好地促进出院诊断书写规范化、科学化以及提高分类编码准确性.方法回顾性对我院2003年1月至2004年12月2339份产科出院病案的出院诊断及其分类编码进行核查.结果调查主要编码2339个,次要编码1580个,错误编码358个,错码率9.1%.误码多由于出院诊断书写不规范,编码员对专科知识掌握不够、不按照先了解病情后编码,分类原则及方法不熟练等原因.结论加强医生分类知识及诊断书写的培训,提高编码员专业知识水平及加强其责任心,才能提高ICD-10分类准确性.     

产科血液保护法进展

在发展中国家出血仍是威胁产妇生命的重要因素。产科大出血是导致产妇死亡的重要原因之一，1994年至1996年联合国关于产妇死亡的报道中认为，在引起产妇死亡的原因中大出血占第三位，死亡率约为5．5／100万，3a共有12例产妇死亡，分别为胎盘早剥4例，前置胎盘3例，产后出血5例。     

产科健康教育的实施与探讨

健康教育是指通过有计划、有组织、有系统的教育活动，促使人们自愿采用有利于健康的行为，消除或降低危险因素、降低发病率，伤残率和致死率，提高生活质量，并对教育效果作出评价。在健康教育中，护士起着举足轻重的作用，而产科护士接触的是孕产妇，如何帮助她们安全顺利渡过妊娠分娩期是现代护理所面临的一个重要课题。     

《中国妇产科临床杂志》2000-2007年创刊8年引文分析

目的分析《中国妇产科临床杂志》2000～2007载文引文情况，以评价其信息接受能力、信息源状况及文献的需求特征。方法采用中国知识资源总库（CNKI）的中国引文数据库检索《中国妇产科临床杂志》2000-2007年所载学术性论文的参考文献，通过引文计量分析方法对其总发文量、篇均引文数、引文语种、引文普赖斯指数等进行分析。结果本刊创刊8年共发文量1172篇，其中，有引文的学术论文1107篇，平均引文率94．45％，篇均引文数8．94条；单篇引文峰值41篇，引文语种以外文为主，占69．69％，其中英文占99．85％；其次为中文，占30．31％。引文类型以期刊为主，占引文总数的73．32％。其次为图书，占26．58％，引文普赖斯指数为50．69％，引用频次前10位的中文期刊文献引用数量占引用中文期刊文献总量的29．41％。结论该刊载文引文率较高，作者文献利用能力较高，引文的时效性较好。     

The placenta: Immunologic or hemodynamic protector of the fetus?

Complete separation of the maternal and fetal circulation during normal pregnancy has been regarded as an extremely important protective factor from the immunologic standpoint. This hypothesis was tested in outbred rabbits in which a direct maternal-fetal parabiosis was established during the last week of pregnancy by implanting an intact maternal omental pedicle subcutaneously into the fetus. A functional cross-circulation, which developed after 48 hours as evidenced by maternal⁵¹Cr-labeled erythrocytes, led to pathologic changes culminating in fetal death within 70 to 80 hours postoperatively. Hyperacute graft rejection, previously postulated as the etiology of these fetal changes, was ruled out since the same characteristic syndrome occurred in similarly treated inbred fetuses syngeneic with their mothers. This study indicates that the absence of direct vascular intercommunication between mother and fetus at the level of the placenta is clearly necessary for physiologic as well as immunologic reasons.