全文获取类型
收费全文 | 26471篇 |
免费 | 2274篇 |
国内免费 | 843篇 |
专业分类
耳鼻咽喉 | 266篇 |
儿科学 | 296篇 |
妇产科学 | 282篇 |
基础医学 | 1065篇 |
口腔科学 | 405篇 |
临床医学 | 2934篇 |
内科学 | 7188篇 |
皮肤病学 | 177篇 |
神经病学 | 599篇 |
特种医学 | 1039篇 |
外国民族医学 | 3篇 |
外科学 | 6837篇 |
综合类 | 4106篇 |
现状与发展 | 4篇 |
预防医学 | 886篇 |
眼科学 | 144篇 |
药学 | 1680篇 |
38篇 | |
中国医学 | 464篇 |
肿瘤学 | 1175篇 |
出版年
2024年 | 63篇 |
2023年 | 645篇 |
2022年 | 1011篇 |
2021年 | 1626篇 |
2020年 | 1535篇 |
2019年 | 1325篇 |
2018年 | 1313篇 |
2017年 | 1112篇 |
2016年 | 1240篇 |
2015年 | 1253篇 |
2014年 | 2298篇 |
2013年 | 2139篇 |
2012年 | 1874篇 |
2011年 | 1969篇 |
2010年 | 1523篇 |
2009年 | 1369篇 |
2008年 | 1255篇 |
2007年 | 1197篇 |
2006年 | 917篇 |
2005年 | 741篇 |
2004年 | 604篇 |
2003年 | 448篇 |
2002年 | 360篇 |
2001年 | 270篇 |
2000年 | 235篇 |
1999年 | 194篇 |
1998年 | 181篇 |
1997年 | 133篇 |
1996年 | 110篇 |
1995年 | 106篇 |
1994年 | 105篇 |
1993年 | 64篇 |
1992年 | 66篇 |
1991年 | 53篇 |
1990年 | 45篇 |
1989年 | 37篇 |
1988年 | 32篇 |
1987年 | 23篇 |
1986年 | 24篇 |
1985年 | 31篇 |
1984年 | 17篇 |
1983年 | 8篇 |
1982年 | 17篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1978年 | 5篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1972年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
61.
钬激光输尿管镜下碎石与经皮肾取石治疗嵌顿性输尿管上段结石的比较 总被引:11,自引:0,他引:11
目的比较钬激光输尿管硬镜碎石与经皮肾取石术治疗嵌顿性输尿管上段结石的疗效。方法106例单侧伴有肾积水的嵌顿性输尿管上段结石,48例采用URL治疗(URL组),58例采用PCNL治疗(PCNL组),统计分析2组的结石清除率及手术并发症。结果术后1 d结石清除率URL组25.0%(12/48)显著低于PCNL组98.3%(57/58)(χ^2=62.065,P=0.000);术后3个月结石清除率URL组77.1%(37/48)显著低于PCNL组100%(58/58)(χ^2=14.831,P=0.000);术后高热(T〉38.5℃)率URL组8.3%(4/48)与PCNL组6.9%(4/58)无统计学差异(χ^2=0.000,P=1.000)。结论对于嵌顿性输尿管上段结石,在有条件且技术成熟的医院PCNL可作为治疗的首选方法。 相似文献
62.
Kohei Hara MD PhD Shigeru Kohno MD PhD Hironobu Koga MD PhD 《Journal of infection and chemotherapy》1996,1(3):166-176
Conclusion Reviewing the history of diagnostic procedures of causative organisms of respiratory infections, invasive techniques such
as the protected specimen catheter (PSB) and bronchoalveolar lavage (BAL) have become the preferred choices because they have
many advantages. These methods cause the patient relatively little discomfort, and permit an early diagnosis since they can
easily be performed at the bedside and the causative organism from the disease site is obtained in cultures. These procedures
can be used not only in patients with community-acquired lung infections, but also in immunocompromised hosts, including those
with blood diseases or following renal transplantation, in patients in intensive care units and in mechanically-ventilated
patients so that the cause can be accurately determined and chemotherapy started quickly, resulting in better therapeutic
efficacy.
Although these invasive procedures are advantageous for the diagnosis of respiratory infections, they also present various
problems which remain to be addressed including minimizing contamination and setting diagnostic threshold values. However,
the importance of accurately determining the causative organism in respiratory infections should be recognized as the most
important factor, and these methods have shown to date to provide the most accurate information to aid in the timely treatment
of respiratory infections in a wide variety of patients. 相似文献
63.
T. Scholz Ø. Mathisen A. Bergan S. Osnes R. Innes T. Pedersen A. O. Aasen O. Søreide 《Transplant international》1997,10(3):180-184
We have introduced and evaluated several modifications of the conventional venovenous bypass (VVBP) in 29 adult patients
undergoing liver transplantation (OLT). A percutaneous technique for insertion of a jugular venous return cannula and a femoral
vein cannula was applied. The inferior mesenteric vein (IMV) was used for splanchnic decompression, which facilitated dissection
of the recipient liver and allowed portal anastomosis to be performed without disconnecting the portal bypass. A heat exchanger
was introduced into the bypass circuit to prevent heat loss. The percutaneous technique prevented complications related to
dissection in the axilla and groin. Hemodynamic characteristics corresponded to those found using the traditional technique.
Complications related to the VVBP were seen in only one patient in whom the femoral catheter was accidentally introduced into
the femoral artery. We conclude that percutaneous cannulas, use of the IMV for splanchnic decompression and the introduction
of a heat exchanger offer significant benefits and that they are safe and reliable.
Received: 23 August 1996 Received after revision: 14 January 1997 Accepted: 27 January 1997 相似文献
64.
Sixteen patients receiving percutaneous endoscopic gastrostomy (PEG) feeding following a period of nasogastric (NG) feeding were investigated to assess acceptance and identify problems by means of a questionnaire. PEG was considered to be superior to NG feeding in terms of tolerance and cosmetic acceptance by 81% and 88% of participants respectively ( P < 0.001). Pain was an infrequent problem. Interruptions to feeding were consideed to be more common with NG feeding by 50% of participants; 38% considered interruptions equally common with both PEG and NG, and 12% considered interruptions more common with PEG feeding ( P = NS). The time for care was equivalent for both methods. Seventy-five percent considered PEG to have made a valuable contribution to enteral feeding. Leakage was however considered to be more frequent in PEG feeding by 81% of participants (compared to 12% who considered leakage to be more common with NG feeding; P < 0.001) and leakage was more frequent at die junctions in the catheter rather than from the stoma. Thirty-one percent of patients with PEG had needed systemic antibiotics for stomal infections. All patients with both PEG and NG feeding needed professional help. Sixty-two percent needed professional help more frequently with PEG than with NG feeding (compared to 19% who considered that the NG tube needed professional help more frequently; P <0.05). We conclude that leakage and infections are major problems in PEG enteral feeding. 相似文献
65.
光镜和电镜观察慢性宫颈炎上皮不典型增生42例,宫颈癌21例,正常对照7例。上皮不典型增生之一是位于深部的储备细胞增生,细胞的核质比大,细胞器少,分化较低。鳞状上皮不典型增生细胞特点是核质比增大,核形不整,核膜内陷,细胞器增多,桥粒和张力原纤维减少。鳞癌细胞的核质比更大,核膜内褶深,细胞器更多,桥粒和张力原纤维很少或消失,分化低的癌细胞尤明显。粘液性腺癌腺上皮深部可见储备细胞转化的癌细胞。 相似文献
66.
脑创伤是目前严重危害人类健康的主要疾病之一,具有较高的致残率和死亡率。而继发性脑损伤是影响脑创伤发展和预后的重要因素之一,适当的治疗可以减轻或避免某些继发性损伤的病理变化,提高患者的疗效,改善预后。近年来,随着对基质金属蛋白基质系(matrix metalloproteinases,MMPs)的不断深入研究,金属蛋白酶系在继发性脑损伤中的作用日益受到人们的重视。本文就基质金属蛋白酶系在脑创伤方面的研究概述如下。[第一段] 相似文献
67.
68.
69.
Albert B. Zajko M.D. Klaus M. Bron William L. Campbell 《Cardiovascular and interventional radiology》1987,10(1):28-31
Biliary obstruction and multiple hepatic abscesses occurred in a patient after ligation of a segmental branch of the right
hepatic duct. The patient was successfully managed by transhepatic biliary drainage and balloon dilatation of an internal
fistula that developed between the ligated duct and a Roux limb of jejunum. Internal biliary fistulas may be dilated using
interventioanl radiologic techniques to permit nonobstructed bile flow. Implications for the nonsurgical treatment' of biliary
strictures are discussed. 相似文献
70.
内科微创肺减容术的研究进展 总被引:1,自引:0,他引:1
传统的外科肺减容术治疗慢性阻塞性肺疾病(COPD)有严格的适应证,并且副作用大、并发症多。于是人们研究出多种基于同样原理但是采用内科微创技术的减容方法。目前常用的内科微创肺减容术有使用单向活瓣、生物蛋白胶等封堵支气管使靶肺萎陷、不张,或采用支气管内药物灌注肺泡加封堵使靶肺组织纤维化等。此外,还有人提出人工旁路增加呼出气量的方法。尽管目前还缺少大规模的随机对照临床试验结果,但是内科微创肺减容术已展现了其巨大的临床应用前景,也将为治疗COPD提供更多的选择。 相似文献