The chronic hepatotoxicity assessment of the herbal formula Zishen Yutai pill

Zishen Yutai pill (ZYP) is an oriental herbal formula, while hepatotoxicity assessment of ZYP was rarely evaluated. Therefore, our aim is to re-evaluate its hepatotoxicity in both normal and carbon tetrachloride (CCl₄) induced chronic liver injury rats. In the normal model, two doses of ZYP (1.575 and 9.450 g kg⁻¹ d⁻¹; i.e. 1 × , 6 × clinical doses) were given orally to rats for 24 weeks. In the chronic liver injury model, 10% CCl₄ was administered to rats abdominally twice a week at a dose of 5 mL kg⁻¹ for 12 consecutive weeks. Administration time started from 4 weeks after the beginning of CCl₄ treatment. Toxicological parameters included mortality, body weight, food consumption, clinical signs, biochemical parameters, gross observation, organ weight, necropsy findings and histopathology were monitored. In the normal model, we found no any mortality or abnormality in clinical signs, relative liver weight, biochemical parameters and histopathology in ZYP treatment groups. In the chronic liver injury model, liver damage related parameter such as ALT was elevated at the high dose of ZYP treatment in contrast to the CCl₄-treated group (P < 0.01). In histopathological assessment, there were no significant difference between ZYP treatment groups and CCl₄-treated group. No observed adverse effect on livers were established for 9.450 g kg⁻¹ d⁻¹ ZYP in the normal rats and 9.450 g kg⁻¹ d⁻¹ ZYP in the injury rats.     

中药灌肠并针灸佐治小儿病毒性肠炎60例疗效观察

目的：观察中药灌肠并针灸对小儿病毒性肠炎的疗效。方法：临床上将110例病儿随机分为治疗组和对照组,对照组不用抗生素,纠正水电解质及酸碱平衡紊乱,并常规口服思密达12包-1包;治疗组：在对照组相同治疗的基础上加用中药30m l-50m l灌肠2次/d,针灸1次/d,观察患儿治疗后症状缓解情况。结果：治疗后,治疗组总有效率96.7%,对照组总有效率68.0%,疗效明显优于对照组,且减少了不良反应。结论：中药灌肠并针灸治疗小儿病毒性肠炎操作简单,使用方便,不良反应少的优点,可明显提高治愈率。     

中药保留灌肠联合吡喹酮治疗血吸虫性结肠病

采用中药保留灌肠联合吡喹酮治疗血吸虫性结肠病并观察其临床疗效，结果显示，经过1～2个疗程治疗后总有效率可达95％。     

欧盟植物药的技术性贸易壁垒对中药出口的影响

目的:研究欧盟植物药在2004/24/EC指令指导下的技术性贸易壁垒,为我国中药成功出口欧盟提供一些思路。方法:从简化注册申请条件的限制、技术标准与认证制度、欧盟注册申报资料等角度探讨中药申请欧盟注册所面临的技术性贸易壁垒,并提出一些相应的对策。结果与结论:首先,加强政府间的沟通合作;其次,建立与国际接轨的中药标准;再次,加强跨国经营,寻找合作伙伴;最后,健全信息咨询机构,充分掌握技术性壁垒信息。     

中药脱敏剂治疗牙本质过敏的临床疗效观察

目的:观察中药脱敏剂治疗牙本质过敏的临床疗效。方法:选取牙本质过敏患者126例,随机分为研究组64例(患牙172颗)、对照组62例(患牙158颗),分别使用中药脱敏剂和氟化钠甘油进行治疗。观察2组患者在治疗后即刻、3个月后、6个月后的疗效,并进行统计学分析。结果:2组疗效比较有显著性差异(P<0.01)。结论:中药脱敏剂可有效治疗牙本质过敏,且使用方便,疗效相对持久。     

退黄外洗液皮肤给药过敏性实验研究

目的:通过动物皮肤给药安全性实验,研究退黄外洗液的安全性,为临床用药提供参考依据。方法:按照国家颁发的皮肤过敏试验标准进行皮肤和全身过敏性实验。结果:退黄外洗液无皮肤及全身过敏反应。结论:本品与皮肤给药相关的特殊安全性试验项目符合临床应用要求,局部或全身皮肤洗用是安全的,可以全身盘浴外洗的方法应用于临床。     

中药饮片商品的现状与教材内容的合理设置

在中药饮片商品现状调查的前提下，分析总结了中药饮片商品品种混乱的类型，认为医与药、教与用结合不够，学科间欠沟通是中药饮片商品品种混乱的原因之一；提出了对中药学、中药鉴定学、中药商品学中中药饮片教学内容合理设置的建议。     

External Application of Herbal Medicine to Acupoints

Application of herbal medicine to acupoints is to regulate the meridians, yin-yang, and qi and blood for preventing and treating diseases through the pharmacological action of herbal medicines and with their stimulation to the acupoints. This article explains how to apply herbal medicines and gave the examples for the treatment of hypertension, asthma, chronic bronchitis and allergic rhinitis. Application of herbal medicines to acupoints is one of the important components of TCM, which shows satisfactory effects in treatment of some chronic diseases.