宫腔镜电切术在子宫内膜息肉手术中的85例疗效观察

[目的]探讨宫腔镜电切术在子宫内膜息肉（endometrial polyps,EP）手术中的疗效及安全性.[方法]选择2009年1月至2013年1月本院行宫腔镜电切术EP患者85例作为治疗组;选择同期在我院行宫腔镜下刮宫术的EP患者73例作为对照组.对比两组术中并发症、术中出血、手术时间及疗效.[结果]治疗组：手术时间：8～20 min,平均（13.6±3.0）min,出血量10～30mL,平均（19.7±4.9）mL.对照组：手术时间：9～35min,平均（20.0±6.4）min,出血量30～50mL,平均（37.4±4.8）mL.两组手术时间、出血量差异有统计学意义（P＜0.05）.术中两组均无子宫穿孔、低钠血症、气栓、术中术后大出血、电热损伤等并发症发生.随访时间：9个月～4年,两组在复发率、月经量改变、贫血症状改善等情况差异显著（P＜0.05）.[结论]宫腔镜电切术用于治疗EP的效果较好.可明显减少EP术后复发.并且术后能明显纠正贫血,改善月经量,恢复子宫正常形态,且副反应小,治疗彻底.     

Surgery-induced behavioral changes in aged rats

Elderly patients may experience impairments in cognition or mood following surgery. To study the development and underlying mechanisms of these postoperative behavioral changes, young (3 months) and aged (18–20 months) male rats were subjected to abdominal surgery followed by behavioral testing during a period of 6 weeks. Microglia activation (IBA-1) and neurogenesis (DCX) were immunohistochemically determined. In separate experiments, the effects of anesthesia and the cytokine response (IL-6) following surgery were evaluated.     

江汉平原疫区居民血防知识与行为调查分析

用ＷＨＯ推荐方法和调查试卷对疫区居民调查发现：血防知识处于较差水平，得分率为４６．３％，以血吸虫病症状了解程度最差；血防行为处于中等水平，得分率为６９．２％；分析发现：此种不平衡系行政干预所至；通过对年龄别和文化程度的分析，得出今后工作重点应为文化程度较低的男性中年人和女性中老年人。     

强噪声对豚鼠耳蜗内电位(EP)及耳蜗动作电位(AP)影响的实时分析

本文对10只豚鼠,在接受强噪声(125dB LP)前、接受噪声同时及噪声后的耳蜗内电位(EP)及耳蜗动作电位(AP)结果进行了分析,发现强噪声对EP值影响较小,对AP参量影响较大。提示:在强噪声作用下,蜗内电位(EP)参量对噪声性声损伤的作用不敏感;噪声对耳蜗损伤的靶器官并不是在血管纹,而是直接损伤毛细胞和神经末梢。     

生化检验线性评价与应用

目的探讨CAP-IRC、EP6-A和改良的Doumas线性评价方法的区别、适用性和在生化检验中的应用。方法采用CAP-IRC、EP6-A、改良的Doumas三种方法对25个临床化学检验项目进行线性评价,比较评价结果的异同。结果在22个临床化学检验项目中,EP6-A方法有14个可直接判断为线性,5个为临床可接受线性,3个为非线性;CAP-IRC方法有6个为直接线性,16个为可接受线性;改良的Doumas方法有12为线性,10个为非线性。结论 EP6-A方法客观,更适用于临床,是目前较理想的线性评价方法。     

血清β-HCG及孕酮联合彩色B超检查对早期异常妊娠诊断价值的探讨

目的 探讨血清β-HCG及孕酮联合彩色B超检查综合判断先兆流产、稽留流产与异位妊娠三种早期异常妊娠疾病,尽早明确诊断,及时正确处理.方法 对316例早期异常妊娠的病例动态监测其血清β-HCG及孕酮值,并行经阴道彩色B超检查.结果 先兆流产组血清β-HCG及孕酮值高于稽留流产组和异位妊娠组.三种疾病经阴道彩色B超检查结合血清β-HCG及孕酮值,可提高诊断率.结论 联合检测血清孕酮与β-HCG值,结合经阴道彩色B超检查,提高临床诊治早期异常妊娠疾病的准确率.     

双侧输卵管同时妊娠1例及文献复习

目的:探讨临床罕见病例——双侧输卵管妊娠的诊断及治疗方法。方法:通过病例报道和相关文献复习,对双侧输卵管妊娠的病因、诊断及治疗作一分析。结果:双侧输卵管妊娠发生率较低,容易漏诊,对患者造成不良影响甚大,早期诊断和治疗尤为重要。结论:辅助生殖技术(ART)为不孕症患者带来福音的同时,在一定程度上增加了异位妊娠(EP)的发生率,尤其是某些特殊类型的EP。对于可疑患者,超声和手术应仔细探查双侧附件的情况,以便早期发现和治疗。     

Modulation of noradrenaline release from the sympathetic nerves of human right atrial appendages by presynaptic EP3- and DP-receptors

Strips of human right atrial appendages were preincubated with [³H]noradrenaline and then superfused with physiological salt solution containing inhibitors of uptake₁ and uptake₂. Tritium overflow was evoked by transmural electrical stimulation (standard frequency: 2 Hz). Prostaglandin E₂ (PGE₂) inhibited the electrically evoked tritium overflow; at the highest concentration investigated, tritium overflow was reduced by about 80% and the pIC_50% value was 7.14. The effect of PGE₂ was not affected by rauwolscine, which, by itself, increased the evoked overflow. Naproxen failed to affect the evoked tritium overflow and its inhibition by PGE₂. The inhibitory effect of PGE₂ on the electrically evoked tritium overflow was mimicked by prostaglandin E₁, the EP₁/EP₃-receptor agonist sulprostone and the EP₂/EP₃-receptor agonist misoprostol with the rank order of potency (pEC_50%): sulprostone (7.68) > misoprostol (7.10) > PGE₁ (6.39). In contrast, PGF_2α, the IP/EP₁-receptor agonist iloprost and the stable thromboxane A₂ analogue U46619 (9,11-dideoxy-11α,9α-epoxy-methanoprostaglandin F_2α) did not change evoked tritium overflow. PGD₂ caused facilitation. These results suggest that the sympathetic nerve fibres innervating human atrial appendages are endowed with presynaptic inhibitory EP₃ and facilitatory DP-receptors. The EP₃-receptors appear not to be tonically activated and do not interact with the α₂-autoreceptors. Received: 11 May 1998 / Accepted: 29 July 1998     

Dynamic functional topography of cognitive tasks

Summary Improved neuroelectric recording and analysis tools are yielding increasingly specific information about the spatial and temporal features of neurocognitive processes. Such tools include recordings with up to 125 channels, digital signal processing techniques, and correlation of neuroelectric measures with anatomical information from magnetic resonance images. These tools, and their application to the study of cognitive functions, are presented in this paper.Acknowledgements: This work was supported by grants from The National Institute of Neurological Diseases, The National Institute of Mental Health, The Air Force Office of Scientific Research and The National Science Foundation. The author gratefully acknowledges the efforts of his scientific collaborators, Drs. S. Bressler, P. Brickett, B. Cutillo, R. Fowler-White, D. Greer, J. Illes, J. Le, N. Morgan and B. Reutter for their contributions to the original research presented here.     

Plastic injection injury of the hand.

A unique case of injection of plastic material into the hand is reported. Treatment was simple because the molten plastic solidified, separated readily from the surrounding tissues and could be withdrawn without fragmentation. There was no evidence of serious damage to the surrounding tissues by the plastic before it has cooled and set. The mechanism of the injury is explained and the need for simple safety precautions is noted.