1981～2000年《南通医学院学报》学术质量指标综合评价

采用文献计量学方法对《南通医学院学报》20卷78期4713篇论文的多项学术质量指标进行统计分析。结果：（1）信息量指数0．55篇／页;（2）单元作者系数2．33人／篇;（3）论文合著率64．52％;（4）出版时滞8．5个月;（5）国家自然科学基金资助等省部以上课题论文86篇;（6）平均引文量4．81条／篇;（7）衰减系数41．6％,其中中文衰减系数54．6％,外文衰减系数33．4％。统计结果表明,信息量指数呈上升趋势,单元作者系数和论文合著率偏低,出版时滞改善显著,基金资助论文数所占,平均引文量偏少,衰减系数增长明显。     

Paradoxical brain embolism shadowing massive pulmonary embolism

Patent foramen ovale is frequently observed in the general population. In case of massive pulmonary embolism, the sudden increase in the right heart cavity's pressure may cause a right-to-left shunting across this foramen, which could be associated with conflicting outcomes. Herein, we report a case of reversible cardiac arrest preceded by seizures, and followed by hemodynamic stability without any vasopressor. A brain CT-scan showed a limited ischemic stroke. Initial echocardiographic assessment revealed an acute cor pulmonale and a right-to-left intracardiac shunt across a large patent foramen ovale, suggesting the diagnosis of massive pulmonary embolism that was lately confirmed by a multidetector CT-angiography. Anticoagulation therapy was rapidly complicated by a hemorrhagic transformation of the ischemic stroke leading to a fatal outcome. This case illustrates the double-edged circulatory effect of shunting across a patent foramen ovale in case of massive pulmonary embolism: it may have limited circulatory failure but caused in the meanwhile a fatal paradoxical brain embolism.