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991.
《Actas urologicas espa?olas》2014,38(4):244-248
ObjectivesTo evaluate the possible effects of Tribulus terrestris herbal medicine in the erectile dysfunction treatment and to quantify its potential impact on serum testosterone levels.Design and methodsProspective, randomized, double-blind and placebo-controlled study including thirty healthy men selected from 100 patients who presented themselves spontaneously complaining of erectile dysfunction, ≥ 40 years of age, nonsmokers, not undergoing treatment for prostate cancer or erectile dysfunction, no dyslipidemia, no phosphodiesterase inhibitor use, no hormonal manipulation and, if present hypertension and/or diabetes mellitus should be controlled. International Index of Erectile Function (IIEF-5) and serum testosterone were obtained before randomization and after 30 days of study. Patients were randomized into two groups of fifteen subjects each. The study group received 800 mg of Tribulus terrestris, divided into two doses per day for thirty days and the control group received placebo administered in the same way.ResultsThe groups were statistically equivalent in all aspects evaluated. The mean (SD) age was 60 (9.4) and 62.9 (7.9), P = .36 for intervention and placebo groups, respectively. Before treatment, the intervention group showed mean IIEF-5 of 13.2 (5-21) and mean total testosterone 417.1 ng/dl (270.7-548.4 ng/dl); the placebo group showed mean IIEF-5 of 11.6 (6-21) and mean total testosterone 442.7 ng/dl (301-609.1 ng/dl). After treatment, the intervention group showed mean IIEF-5 of 15.3 (5-21) and mean total testosterone 409.3 ng/dl (216.9-760.8 ng/dl); the placebo group showed mean IIEF-5 of 13.7 (6-21) and mean total testosterone 466.3 ng/dl (264.3-934.3 ng/dl). The time factor caused statistically significant changes in both groups for IIEF-5 only (P = .0004), however, there was no difference between the two groups (P = .7914).ConclusionsAt the dose and interval studied, Tribulus terrestris was not more effective than placebo on improving symptoms of erectile dysfunction or serum total testosterone. 相似文献
992.
颈性眩晕是常见的骨科疾病,主要以老年人为主,已严重影响了人们的生活与工作。近年来中医通过多种特色疗法取得了很好疗效。但目前没有统一的辨证分型和理法方药,还需进一步研究。 相似文献
993.
老年病体质特点包括脏腑失养、精血亏虚;心肝血虚、神气不足;肺脾气弱、正气内虚等。"天人相应,整体相关;因人施治,因地制宜;内外相顾,动静结合;重视情志,强调气机"中医疗法与现代医学对老年病的多学科治疗。 相似文献
994.
995.
恶性腹水是肿瘤常见并发症,常规治疗方法疗效欠佳。中医药治疗恶性腹水近年来取得较满意的效果,有内治、外治、腔内注射、艾灸等治疗方法。 相似文献
996.
997.
998.
Wei Yang ;Wen Zhang ;Yanming Xie ;Bing Han 《Journal of traditional Chinese medicine》2014,(5):604-608
OBJECTIVE: To systematically investigate the safety of Xingxue Shuxuening injection(SXN) in preand post-marketing, and to ensure clinical drug safety.METHODS: Strict quality control in raw herb selection and production processes was adopted and pharmacology research on SXN was performed by the drug manufacturing company, Heilongjiang ZBD Pharmaceutical Co., Ltd. We systematically reviewed the safety literature of Xingxue SXN. Adverse drug reaction(ADR) data of the drug, extracted from Spontaneous Reporting System(SRS), and clinical characters based on 20 hospital information systems(HIS) in China, were analyzed. Large-scale prospective safety monitoring and Risk Minimization Action Plans(Risk MAPs) of XingxueSXN were carried out.RESULTS: The quality of SXN was stable and controllable when it was produced. Drug toxicology studies found no effect on rabbits with hemolytic or condensed, local stimulation and muscle stimulation, and no allergic reactions in guinea pigs. The ADRs of Xingxue SXN were dizziness, phlebitis,and vomiting based on SRS data. The injection did not conform to instructions in clinical practice when we analyzed HIS database, and patient's abnormal blood urea nitrogen levels may be related to the drug, when analyzed using the propensity score method. A nested case-control study was designed and performed to analyze the influencing factors of suspected allergic reactions to SXN. The study showed that patients with an allergy history were more prone to allergic reactions(P〈0.001),and some medicine combinations could cause allergic reactions.CONCLUSION: These studies have established a body of evidence on Xingxue SXN safety, and provide a good model for Chinese medicine injection for clinical safety. The Xingxue SXN production process and toxicology research indicate the safety of the injection. However, the use of the injection is not consistent with instructed clinical practice.Xingxue SXN causes ADRs perhaps from inappropriate usage or its 相似文献
999.
目的:研究分析不同用药方案治疗幽门螺杆菌(HP)相关性十二指肠溃疡的临床效果。方法选取2011年9月-2013年11月期间,在本院接受治疗的68例幽门螺杆菌相关性十二指肠溃疡患者,随机分为观察A组、观察B组和对照组,每组24例。对照组患者采用常规的十二指肠溃疡治疗方法,观察A组采用奥美拉唑联合阿莫西林、克拉霉素治疗,观察B组在西药治疗的基础上加用中药消溃平汤剂,比较三组患者的HP根除率、十二指肠溃疡的愈合情况及溃疡的复发率。结果观察A组和观察B组的HP根除率91.7%、95.8%显著高于对照组的HP根除率54.2%(P〈0.05);三组患者的十二指肠溃疡的愈合情况比较差异无统计学意义(P〉0.05);治疗后2年回访中,观察A组和观察B组的的复发率8.3%、4.2%显著低于对照组的复发率37.5%,差异具有统计学意义(P〈0.05)。结论在治疗十二指肠溃疡的同时给予抗HP治疗的临床效果显著,不仅提高了溃疡愈合速度,而且有效预防溃疡的复发,值得临床推广和应用。 相似文献
1000.
本研究从患者主观观念转变、诊疗价格下降和中西医结合诊疗理念的发展3个方面,介绍了在中医科构建主动服务模式的可行性,重点从分配中医科医生的服务科室和建立服务制度两个方面论述了主动服务模式的构建方法,并对主动服务模式未来工作的开展提出了可行的建议。 相似文献