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81.
82.
目的 探讨后路经皮内窥镜下颈椎椎间盘切除术的安全范围。 方法 选取20具成人颈椎标本,分别测量C3/C4至C6/C7各节段左右两侧V点与硬脊膜外侧距离、V点与椎动脉水平及垂直距离、小关节面宽度,并进行统计学比较。 结果 V点与硬脊膜外侧距离为:左(1.31±0.32)~(2.46±0.60) mm,右(1.29±0.35)~(2.75±0.45) mm,各节段间差别有统计学意义,同一水平左右差别无统计学意义;V点与椎动脉水平距离为:左(2.17±0.42)~(5.10±0.93) mm,右(1.99±0.39)~(5.00±0.71) mm,各节段间差别有统计学意义,同一水平左右差别无统计学意义;V点与椎动脉垂直距离为:左(11.05±1.06)~(13.47±1.12)mm,右(11.33±1.20)~(13.61±1.01)mm,同一水平左右侧差别有统计学意义,节段间比较C3/C4与C4 /C5无明显差异,其余节段间差别均有统计学意义;小关节面宽度为:左(10.79±0.93)~(12.66±0.88) mm,右(10.86±0.68)~(12.54±0.70)mm。 结论 后路经皮内窥镜下颈椎椎间盘切除术的安全范围宜控制在距V点内侧C3/C4至C6/C7各水平1.20~2.00 mm;磨除范围距V点外侧C3/C4至C6/C7各水平超过2.00~5.00 mm时可能到达椎动脉体表投影处,因此需注意此时的手术进入深度宜控制在:C3/C4~C6/C7各节段距V点11.00~14.00 mm。 相似文献
83.
目的探讨HPV16感染及其E6/E7基因变异与宫颈病变的相关性。方法采用导流杂交技术进行HPV感染分型检测,PCR扩增出80份HPV16阳性宫颈病变的E6/E7基因、克隆入pMD18-T载体,双向测序分析基因变异与宫颈病变相关性。结果HPV16在宫颈病变患者中的检出率最高为33.3%(154/463),与病变程度相关(P<0.05)。E6/E7基因72份测序成功,DNA序列变异发生率为88.9%(64/72)。氨基酸序列E6-D32E(T96G)和E7-N29S(A86G)位点突变同时伴随存在,D32E/N29S的检出率为38.9%(28/72),与宫颈病变程度相关(P<0.05)。结论HPV16是北京地区来源的宫颈病变中最常见的致病型,其D32E/N29S变异与病变程度相关。 相似文献
84.
目的 探讨术前颈椎过伸功能与颈椎后路单开门椎管扩大成形术后前凸角度丢失的关系。方法 回顾性分析首都医科大学大兴教学医院骨科2017年1月-2018年12月58例行颈椎后路单开门椎管扩大成形术患者临床资料,其中男45例、女13例,年龄49~85岁(平均64.8岁)。术前测量患者中立侧位X线片上的T1倾斜角、矢状面垂直轴(SVA),以及中立侧位、过伸位X线片的C2~C7 Cobb角。随访12~24个月,术后再次测量中立侧位X线片上的C2~C7 Cobb角。术前颈椎过伸功能测量值为术前过伸位X线片C2~C7 Cobb角度减去术前中立侧位X线片C2~C7 Cobb角。前凸角度丢失量为术前中立侧位片C2~C7 Cobb角减去末次随访时中立侧位片C2~C7 Cobb角。依据58例患者术前颈椎过伸功能均值(8.7°)分为两组,≥8.7°为A组,<8.7°为 B 组。比较两组患者术前及术后影像及临床资料,同时对58例患者的影像学资料与临床资料进行相关性分析。结果 A组25例患者年龄54~83岁,B组33例患者年龄49~85岁,两组患者术前年龄、性别、疾病种类差异均无统计学意义(P值均>0.05)。术前A组颈椎过伸功能(14.09°±4.75°)大于B组(4.62°±2.54°),A组T1倾斜角(17.00°±3.40°)小于B组(29.68°±6.34°),颈椎前凸角度丢失[1.10(-0.85,4.00)]小于B组[8.60 (7.70,12.40)],差异均有统计学意义(P值均<0.01)。颈椎过伸功能与前凸角度丢失之间呈负相关(r=-0.965, P<0.01),T1倾斜角与前凸角度丢失之间呈正相关(r=0.954, P<0.01),颈椎过伸功能与T1倾斜角呈负相关(r=-0.900, P<0.01);SVA与T1倾斜角、颈椎过伸功能、术后前凸角度丢失均无相关性(r=-0.065、0.216、-0.202, P>0.05)。术后JOA评分改善率与过伸角度变化、SVA及T1倾斜角均无相关性(r=0.201、-0.034、-0.213, P值均>0.05)。A组术后JOA改善率为69%±23%,B 组术后JOA改善率为62%±23%,两组差异无统计学意义(t=1.147, P>0.05)。术后Odom's分级评价A组优良率为88.0%(22/25),B组优良率为63.6%(21/33),差异有统计学意义(χ2 =4.403, P<0.05)。结论 对于后路单开门椎管扩大成形术患者,颈椎过伸功能与前凸角度丢失存在相关性,术前过伸功能越低,术后越易发生前凸角度丢失,可作为术前预判术后颈椎曲度变化的参数之一。 相似文献
85.
D. M. Vogter J. L. Culberson S. S. Schochet O. F. Gabriele H. H. Kaufman 《Acta neurochirurgica》1987,84(3-4):136-139
Summary High spinal (cervical and upper thoracic) dysrhaphism usually involves either a meningocele or a dermal sinus tract. These high spinal lesions can have a complex intradural anatomy at the level of the lesion (as this case reports) and are associated with an increased incidence of lower spinal occult dysrhaphic anomalies. It is therefore recommended that patients with high spinal dysrhaphism undergo radiological evaluation of the entire spine to identify those patients with intradural anomalies, define the anatomy for surgery, and investigate the lower spine for associated occult anomalies. 相似文献
86.
Juan F. Martinez-Lage Miguel A. Perez-Espejo José Masegosa Máximo Poza 《Child's nervous system》1986,2(4):208-210
The case of a 4-year-old girl who developed bilateral brain abscesses complicating skull traction is reported. Crutchfield tongs were used to reduce a fracture dislocation at C2–3. Presenting symptoms consisted of headaches and focal seizures. Surgical treatment and antibiotics using serial CT led to a satisfactory outcome. This is the first reported case of this complication in a child. The current literature is reviewed.To whom offprint requests should be addressed at Avda. Pio Baroja 4, 30011 Murcia, Spain 相似文献
87.
Srikanth Kasturi Arvind Muthirevula Amulya Siddarameshwar Gadennavar Vijay Cholenahalli Lingaraju 《Indian Journal of Thoracic and Cardiovascular Surgery》2021,37(3):338
Penetrating neck trauma, though rare, carries a high morbidity and mortality risk if not recognized promptly, due to the presence of vital neurovascular and airway elements within a closed compartment. We describe the unique presentation of a high zone 1 anterior midline cervical stab injury with bilateral large pneumothoraces and extensive pneumomediastinum. Understanding the respiratory mechanics and a high clinical suspicion will help to recognize such complications of tracheobronchial injuries and their timely management is key to salvage of these patients. 相似文献
88.
Syed Ifthekar Kaustubh Ahuja Samarth Mittal Bhaskar Sarkar Gagan Deep Watson Thomas Pankaj Kandwal 《Indian Journal of Orthopaedics》2021,55(3):673
BackgroundInjuries involving upper cervical spine are serious and fatal injuries which are associated with alteration of normal occipital–cervical anatomy. These injuries may result in permanent neurologic deficits or neck deformity if not treated in a timely and appropriate manner.ObjectiveTo evaluate the outcomes of neglected upper cervical spine injuries treated by various methods.Study designRetrospective study.Materials and methodsTwelve patients attending ER or OPD with a history of neck trauma and who were diagnosed with fractures and fracture dislocations C1 and C2 were included in the study. Fresh injuries sustained within a week were excluded from study. The outcomes were measured in terms of improvement in VAS, ODI Scores and correction of the neck deformity. Surgical parameters like duration of surgery and blood loss were also observed.ResultsEleven males and one female. The mean age was 40.9 ± 16.9 (07–67 years). Eleven patients underwent posterior instrumentation, while one patient was treated anteriorly. The mean delay in presentation was 28 ± 8.67 days (15–42 days). The mean duration of surgery was 188.3 ± 34.35 min (120–240 min), average blood loss was 350 ± 111.8 ml (150–600 ml). The mean VAS improved from 8.45 ± 0.89 to 3.9 ± 0.51 (p < 0.05). The mean ODI Pre-operatively was 88.45 ± 5.89 which improved to 31.9 ± 4.01 (p < 0.05). The neck deformity/torticollis was corrected in all the patients.ConclusionsNeglected upper cervical spine injuries are difficult to treat and a posterior approach is helpful in reducing the subluxations indirectly and to obtain a posterior fusion. 相似文献
89.
90.
Seongmin Kim Kyung Jin Min Sanghoon Lee Jin Hwa Hong Jae Yun Song Jae Kwan Lee Nak Woo Lee 《Asian journal of surgery / Asian Surgical Association》2021,44(1):174-180
Background/ObjectiveRecent prospective studies have shown poorer oncologic outcomes following minimally invasive surgery, which has led many surgeons to deeply inspect their practices. We reviewed our experience and evaluated the results of radical hysterectomy in patients with early stage cervical cancer.MethodsThis retrospective study included patients with early stage cervical cancer (Ia1 - IIa1) who were treated with radical hysterectomy from May 2006 to Dec 2016. Patients were divided into three groups according to the surgical approach: radical abdominal hysterectomy (RAH), laparoscopic radical hysterectomy (LRH), and robot-assisted radical hysterectomy (RRH).ResultsLearning curves of each type of surgery were obtained using the cumulative sum method. Survival rates were compared using Kaplan–Meier curves. To analyze the learning curve of a single surgeon, 89 patients were selected from the whole population. Learning curves of each group showed two distinct phases. The minimum number of cases required to achieve surgical improvement were 16 in RAH, 13 in LRH, and 21 in RRH. Progression-free survival (PFS) and overall survival did not vary between RAH and minimally invasive surgery (MIS) (p = .828 and p = .757, respectively). However, when stratified by the phases of the learning curves, patients included in the early phase of MIS showed a poorer PFS (p = .014).ConclusionsSurgical proficiency could significantly affect the oncologic outcome in MIS. A prospective study regarding sufficient surgical competence is necessary for elaborate analysis of the feasibility of minimally invasive radical hysterectomy. 相似文献