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51.
Akshay Pratap Devendra Kumar Gupta Chandra Shekhar Agrawal Rakesh Kumar Pandit Shailesh Adhikary Anand Kumar Awadhesh Tiwari Satyendra Narayan Singh 《International journal of urology》2007,14(3):198-202
OBJECTIVES: We analyzed the methods and outcomes of urethroplasty in men with complex urethral disruptions. METHODS: The medical records of 40 men with complex urethral disruptions were analyzed. Surgical methods were individualized according to stricture location, severity and length of the stricture, bladder neck characteristics and presence of complicating factors. Patients were divided into four groups based on the above characteristics. RESULTS: End-to-end urethroplasty performed in six patients with short bulbar strictures (<3 cm) was successful in all. Elaborated perineal repair was performed in 10 patients with intermediate (3-6 cm) strictures with or without complicating factors. Elaborated perineal repair with urethral substitution was performed in nine patients with long segment stricture (>6 cm). Abdominal transpubic repair was successfully applied to patients with rectourethral fistula or lacerated bladder neck. Success rate of anastomotic urethroplasty was 95% while over all success rate was 85%. CONCLUSION: Guidelines for urethral reconstruction of complex urethral disruptions are predicated on stricture length, location, bladder neck characteristics and associated complicating factors. End-to-end urethroplasty with stricture excision is highly reliable for short strictures for which previous operative repair have failed. Elaborated perineal repair is extremely versatile for intermediate and longer strictures with associated complicating factors. Abdominal transpubic urethroplasty is effective for patients with rectourethral fistula or lacerated bladder neck. 相似文献
52.
H. Inaba M.D. J. Sato H. Uchida M. Sakurada T. Ohwada T. Mizuguchi 《Acta anaesthesiologica Scandinavica》1988,32(5):374-378
Fluctuating PEEP (F-PEEP) is a newly developed PEEP in which end-expiratory pressure (EEP) is periodically changed within a certain range. In a dog model with unilateral lung injury induced by the introduction of hydrochloric acid, F-PEEP in which the EEP was periodically changed from 0.5 to 1.5 kPa at periods of 6 min, and conventional PEEP (C-PEEP) with an optimized EEP of 1.0 kPa, were each applied for 30 min. F-PEEP produced a significantly greater improvement of PaO2 and intrapulmonary shunt (QS/QT) than C-PEEP, and at the low EEP phase, the greatest improvement accompanied by an increased dynamic compliance and a large cardiac output was obtained. These results suggest that F-PEEP provides a useful mode of artificial ventilation for the treatment of unilateral lung injury. 相似文献
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56.
Sources of P300 attenuation after head injury: Single-trial amplitude, latency jitter, and EEG power
Single trial amplitude, latency jitter, and electroencephalographic (EEG) power were examined as sources of the group difference in averaged P300 amplitude among 15 traumatically brain injured and 20 control individuals in an auditory oddball paradigm. Mean amplitude of the individual trials was highly correlated with the amplitude of the averaged P300, with little additional unique variance attributable to latency jitter or EEG power. The group difference in P300 amplitude was also explained by the mean amplitude of the single trials. These results support the robustness of the event-related potential averaging technique within the paradigm used. 相似文献
57.
This study demonstrates that ZnSO4 induced chemical trauma results in an in situ regeneration of the olfactory epithelium which, when maintained in vitro, provides an enriched population of olfactory neurons. Therefore, the ability of the olfactory epithelium to respond to chemical trauma with increased mitotic activity can be used to increase growth of neurons in culture. Tissue obtained from normal or vehicle-treated adult mice produced few olfactory neurons, when maintained in culture, compared to cultures established from tissue following an in situ ZnSO4 trauma. Maximal neuronal yields were obtained in cultures established from tissue that was removed 4–6 days following chemical trauma. The morphological appearance and the presence of cell specific intermediate filament proteins were used to classify the cell types in these olfactory epithelial cultures. Single cells and aggregates of cells which were immunopositive for keratin, but immunonegative for neurofilament protein and GFAP, were identified as epithelioid. Flattened polygonal cells immunopositive for GFAP were identified as glia. A small population of flattened cells was immunonegative for all of the antibodies used in this study. Cells that had processes were immunonegative for GFAP and keratin. Some were immunopositive for 200 kDa and 160 kDa neurofilament proteins but immunonegative for the 68 kDa neurofilament protein. A few of these cells showed positive immunoreactivity with the olfactory marker protein (OMP) antibody and most likely represented the most mature olfactory neurons in the cultures. This trauma-induced culture model using olfactory tissue from adult mice can serve as a source of CNS neurons for comparison with cultured embryonic neurons. 相似文献
58.
狗脊髓截除自体隐神经大网膜移植的初步观察 总被引:3,自引:0,他引:3
实验用6只狗于T13处切除脊髓8mm,局部用隐神经、大网膜移植。对照组6只狗单纯切除脊髓8mm。术后3个月、6个月实验组动物全部恢复到C/Ⅲ级功能,组织学切片见移植神经有不同程度存活,可记录到股四头肌、胫前肌电位。对照组动物仅达到0/0~A/I织功能,组织学切片见脊髓缺损处为结缔组织,诱电位波形消失。分析了影响脊髓神经功能恢复的原因。 相似文献
59.
神经移位修复臂丛神经根性撕脱伤 总被引:3,自引:2,他引:1
1987年7月~1994年6月,对21例臂丛神经根性撕脱伤采用神经移位修复。其中复合移位4组神经(膈神经、副神经、颈丛运动支、肋间神经)者1例,3组(膈神经、副神经、颈丛运动支)者6例,2组(膈神经、副神经)者9例,1组(膈神经或颈丛运动支或肋间神经)者5例。术中发现臂丛神经变异1例,对4例合并锁骨下动脉损伤者,在神经移位的同时进行血管修复,促进患肢的血液循环,有利于神经的康复。随访到19例,随访时间为8个月~6年2个月,优良率达73.7%。认为,神经移位术是修复神经根性撕裂伤的常规方法,合并血管损伤者也应同时修复,对促进神经功能恢复有利 相似文献
60.
刘达恩 《中国修复重建外科杂志》1997,11(2):83-85
总结胸腹轴型皮瓣早期修复上肢不同部位的深度蛇伤溃疡的经验,评价其应用价值。本组16例,胸脐皮瓣2例,侧胸腹皮瓣1例,髂腰皮瓣5例,下腹皮瓣6例,下腹分叶皮瓣1例,髂腰加下腹Y形皮瓣1例。术后1例皮瓣远端坏死,3例轻度感染,16例断蒂后全部成活。随访3个月~7年,皮瓣质地和弹性均好,手功能基本恢复。认为,带蒂胸腹轴型皮瓣是修复上肢深度蛇伤溃疡理想的方法。 相似文献