香菇多糖注射液对慢性乙型肝炎外周血单个核细胞膜IL—2受体表达的影响

The effects of lentinan on peripheral blood mononuclear cell (PBMC) expression of IL-2 receptor in patients with chronic hepatitis B in vitro and in vivo were studied. The expression percentage of IL-2 receptor in 44 patients with chronic hepatitis before treatment was 36.74 +/- 7.74, which was lower than healthy subjects, and was 48.92 +/- 3.79 after 2 months treatment of lentinan, which was approximated the normal control. PBMC from 30 patients with chronic hepatitis B were cultured in vitro with or without lentinan. The percentage of expression IL-2 receptor was 12.81 +/- 2.62 without lentinan and was 35.70 +/- 4.87 in the presence of lentinan. The concentration of lentinan stimulating expression of IL-2 receptor was between 0.2 to 200 g.ml-1. The results suggest that lentinan stimulates expression of IL-2 receptor on PBMC, which is associated with the therapeutic effectiveness of lentinan treatment.     

十八例颅脑外伤所致精神障碍临床分析

本文对符合CCMD-2诊断标准的18例颅脑外伤性精神障碍进行临床分析，发现具有男性，五人，性格急躁好胜等要素的占多数，受伤原因以工作意外为多，诊断上以颅脑外伤所致精神病为多。本文并对上述结果及颅脑外伤与精神障碍的关系进行简略的讨论。     

HER-2/neu原癌基因与人类癌症

HER－2／neu（C－erb－B－2）原癌基因编码185kD蛋白质，其结构与表皮生长因子受体（EGFR）具有广泛的同源性，也是具有酪氨酸蛋白淑游活性的持定生长因子的受体。HER－2／neu原癌基因可通过点突变扩增及过量表达激活，而且与多种人类病症的恶性有关，可以作为新的抗癌疗法的靶子。